Pamidronato

Zvemukati

• Zvairatidza Pamidronate
• Mutengo wePamidronato
• Mativi Akakomba ePamidronate
• Contraindications yePamidronate
• Mashandisiro ekushandisa Pamidronate

Pamidronate ndiyo chinhu chinoshanda mune anti-hypercalcemic mushonga unozivikanwa nekutengesa seAredia.

Uyu mushonga wekushandisa jekiseni unoratidzirwa pachirwere chePaget, osteolysis sezvo ichivhiringidza kupora kwemapfupa kuburikidza nenzira dzinoverengeka, kudzikisira zviratidzo zvezvirwere.

Zvairatidza Pamidronate

Paget chirwere chepfupa; hypercalcemia (inosangana neoplasia); osteolysis (inokonzerwa nechirwere chepamu kana myeloma).

Mutengo wePamidronato

Mutengo wemushonga hauna kuwanikwa.

Mativi Akakomba ePamidronate

Yakaderera potasium yeropa; yakaderera phosphates muropa; kuputika kweganda; kuomesa; kurwadziwa; palpitation; kuzvimba; kuzvimba kwetsinga; yakaderera low fever.

Muzviitiko zvePaget's Disease: kuwedzerwa kweropa; kurwadziwa kwepfupa; kurwadziwa nemusoro; kurwadza kwemajoini.

Mune zviitiko zveosteolysis: kupererwa neropa; kurasikirwa nenzara; kuneta; kunetseka kufema kugaya; marwadzo emudumbu; kurwadza kwemajoini; kukosora; musoro.

Contraindications yePamidronate

Dambudziko rePamuviri C; kuyamwisa: varwere vane allergies kune bisphosphonates; Hipersensibility kune chero yeiyo fomu yezvinhu

Mashandisiro ekushandisa Pamidronate

Jekiseni Kushandisa

Vakuru

• Hypercalcemia: 60 mg yakapihwa anopfuura maawa mana kusvika makumi maviri nemana (yakanyanya hypercalcemia - yakagadziriswa serum calcium yakakura kupfuura 13.5 mg / dL - inogona kuda 90 mg inotarisirwa kupfuura maawa makumi maviri nemana).
• Varwere vane hutachiona hwehutachiona kana vane hypercalcemia ine unyoro: 60 mg inotarisirwa kupfuura maawa mana kusvika makumi maviri nemana.

Misoro kumusoro: kana hypercalcemia ikadzokazve, kurapwa kutsva kunogona kutariswa sekureba sekunge mazuva manomwe apfuura.

• Chirwere chePaget chepfupa: Yese dosi ye90 kusvika ku180 mg panguva yekurapa; iyo yakazara dose inogona kupihwa pa30 mg zuva nezuva kwemazuva matatu akateedzana kana 30 mg kamwe pasvondo kwevhiki dzitanhatu. Chiyero chehutongi chinogara chiri 15 mg paawa.
• Tumor-induced osteolysis (mukenza yemazamu): 90 mg inotarisirwa kupfuura maawa maviri, ese matatu kana mana mavhiki; (mu myeloma): 90 mg inotarisirwa kupfuura maawa maviri, kamwe chete pamwedzi.