Chii chinonzi Pancytopenia, zviratidzo uye zvikonzero zvikuru

Zvemukati

• Zviratidzo zvikuru
• Zvinokonzera pancytopenia
• Sei kuongororwa
• Kurapwa kunoitwa sei

Pancytopenia inowirirana nekuderera kwemasero eropa ese, ndiko kuti, ndiko kuderera kwenhamba yemasero matsvuku eropa, leukocyte nemaplatelet, izvo zvinokonzeresa zviratidzo nezviratidzo zvakaita sekukweva, kuneta, kupwanya, kubuda ropa, fivhiri uye kutapukira kuzvirwere.

Inogona kusimuka kungave nekuda kwekuderera kwekugadzirwa kwemasero nemongo wemapfupa, nekuda kwezviitiko zvakaita sekushomeka kwevhitamini, hosha dzechibereko, leukemia kana leishmaniasis, pamwe nekuparadza kwemasero eropa muropa, nekuda kwekuzvidzivirira kana kukurudzira zviito zvekuita. zveiyo spleen, semuenzaniso.

Kurapa kwepancytopenia kunofanira kuitwa zvinoenderana nemirayiridzo yechiremba mukuru kana wehematologist zvinoenderana nechikonzero cheiyo pancytopenia, iyo inogona kusanganisira kushandiswa kwecorticosteroids, immunosuppressants, mishonga inorwisa mabhakitiriya, kuwedzerwa ropa, kana kubviswa kwepleen, semuenzaniso, izvo zvinongoratidzwa chete zvichienderana nezvinodiwa nemurwere wega wega.

Zviratidzo zvikuru

Zviratidzo nezviratidzo zve pancytopenia zvine chekuita nekudzikiswa kwemasero matsvuku eropa, leukocyte uye maplatelet muropa, iwo makuru ari:

Zvichienderana nezvenyaya yacho, panogona zvakare kuve nezviratidzo nezviratidzo zvinokonzerwa nechirwere chinokonzeresa pancytopenia, senge dumbu rakawedzeredzwa nekuda kwekukura kwepleen, yakawedzera lymph node, kukanganisika mumapfupa kana shanduko paganda, semuenzaniso.

Zvinokonzera pancytopenia

Pancytopenia inogona kuitika nekuda kwemamiriro maviri: apo mwongo wepfupa usingaburitse masero eropa nenzira kwayo kana kana mwongo wemapfupa waburitsa nenzira kwayo asi maseru anoparadzwa muropa. Zvinonyanya kukonzera pancytopenia ndezvi:

• Kushandisa zvinodhaka zvine chepfu, senge mamwe maantibayoti, chemotherapy, mishonga yekudzvinyirira, maanticonvulsants uye sedatives;
• Migumisiro ye radiation kana makemikari vamiririri, senge benzene kana DDT, semuenzaniso;
• Kushomeka kwevhitamini B12 kana folic acid muchikafu;
• Zvirwere zvemagen'a, senge Fanconi's anemia, congenital dyskeratosis kana chirwere cheGaucher;
• Matambudziko emongo, senge myelodysplastic syndrome, myelofibrosis kana husiku paroxysmal hemoglobinuria;
• Zvirwere zvekuzvidzivirira, senge lupus, Sjögren's syndrome kana autoimmune lymphoproliferative syndrome;
• Zvirwere zvinotapukira, senge leishmaniasis, brucellosis, tibhii kana HIV;
• Gomarara, senge leukemia, yakawanda myeloma, myelofibrosis kana metastasis yemamwe marudzi ekenza kune mwongo wemapfupa.
• Zvirwere zvinokurudzira chiito chepesi uye masero ekudzivirira emuviri kuparadza masero eropa, akadai sechiropa cirrhosis, myeloproliferative zvirwere uye hemophagocytic syndromes.

Uye zvakare, hosha dzinotapukira dzakakomba dzinokonzerwa nehutachiona kana hutachiona, senge cytomegalovirus (CMV), inogona kumutsa yakasimba immune immune mumuviri, inokwanisa kuparadza masero eropa nenzira yakaoma panguva yehutachiona.

Sei kuongororwa

Kuongororwa kwepancytopenia kunoitwa kuburikidza nehuwandu hweropa, umo mazinga emasero matsvuku eropa, leukocyte uye maplatelet akaderedzwa muropa anoongororwa. Zvisinei, zvakakoshawo kuziva chikonzero chakakonzera pancytopenia, iyo inofanira kuitwa kuburikidza nekuongororwa kwechiremba mukuru kana wehematologist kuburikidza nekucherechedza nhoroondo yekliniki uye kuongororwa kwepanyama kunoitwa pamurwere. Uye zvakare, mimwe miedzo inogona kukurudzirwa kuti uone chinokonzeresa pancytopenia, senge:

• Serum iron, ferritin, transferrin saturation uye reticulocyte kuverenga;
• Chipimo chemavhitamini B12 uye folic acid;
• Kutsvaga kwehutachiona;
• Ropa rinovhara chimiro;
• Immunological bvunzo, senge yakananga Coombs;
• Myelogram, umo mapfupa emapfupa anoshuvira kuwana rumwe ruzivo nezve hunhu hwemasero munzvimbo ino. Tarisa kuti myelogram inogadzirwa sei uye painoratidzwa;
• Bone marora biopsy, ayo anoongorora hunhu hwemasero, kuvapo kwekupinda nekenza kana zvimwe zvirwere uye fibrosis. Tsvaga kuti marrow biopsy inoitwa sei uye ndeyei.

Ongororo dzakananga dzinogona zvakare kurayirwa chirwere icho chinofungidzirwa nachiremba, senge immunoelectrophoresis yeakawanda myeloma kana pfupa tsika yekuziva hutachiona, senge leishmaniasis, semuenzaniso.

Kurapwa kunoitwa sei

Kurapa kwepancytopenia kunotungamirwa nehematologist zvichienderana nechikonzero chayo, uye kunogona kusanganisira kushandiswa kwemishonga inoita zvekuzvidzivirira, seMethylprednisolone kana Prednisone, kana immunosuppressants, seCyclosporine, mune autoimmune kana kuzvimba zvirwere. Uye zvakare, kana pancytopenia inokonzerwa nekenza, kurapwa kunogona kusanganisira kupinza kwemongo.

Panyaya yehutachiona, chaiwo marapirwo anoratidzwa kune yega microorganism, senge maantibayoti, antivirals kana pentavalent antimonials mune leishmaniasis, semuenzaniso. Kuwedzerwa ropa hakuwanzo kuratidzwa, asi zvinogona kudikanwa mune zvakakomba zviitiko zvinoda kukurumidza kupora, zvinoenderana nechakonzera.