Munyori: Clyde Lopez
Zuva Rekusika: 24 Chikunguru 2021
Gadziridza Zuva: 15 Mbudzi 2024
Anonim
Pharmacogenetic Miedzo - Mushonga
Pharmacogenetic Miedzo - Mushonga

Zvemukati

Chii chinonzi pharmacogenetic kuyedza?

Pharmacogenetics, inonziwo pharmacogenomics, ndiko kuongorora kwekuti majini anokanganisa sei kupindura kwemuviri kune mimwe mishonga. Magene zvikamu zveDNA zvakapfuudzwa kubva kuna mai nababa vako. Ivo vanotakura ruzivo rwunotarisa hunhu hwako hwakasarudzika, senge kukwirira uye ruvara rwemaziso. Majini ako anogona zvakare kukanganisa kuchengetedzeka uye kubudirira kwechimwe chinhu mushonga chingave chako.

Majini anogona kuve chikonzero chemushonga mumwe chete pane iwo iwo muyero unokanganisa vanhu munzira dzakasiyana kwazvo. Majini anogona zvakare kuve chikonzero nei vamwe vanhu vaine yakaipa mhedzisiro kumushonga, nepo vamwe vasina.

Pharmacogenetic kuyedza kunotarisa mamwe majeni kubatsira kuona mhando dzemishonga uye madhiri ayo angave akakukodzera.

Mamwe mazita: pharmacogenomics, pharmacogenomic kuyedza

Chii chinoshandiswa?

Pharmacogenetic kuyedza kunogona kushandiswa ku:

  • Tsvaga kana mumwe mushonga ungashanda kwauri
  • Tsvaga kuti ndeipi yakanyanya dheseti inogona kunge iri yako
  • Fungidzira kuti uchave uine chakakomba divi mhedzisiro kubva kumushonga

Nei ini ndichida kuyedzwa kwemakemakemikari?

Anokuchengetedza hutano anogona kuraira bvunzo idzi usati watanga mumwe mushonga, kana kana uri kutora mushonga usiri kushanda uye / kana kukonzera mhedzisiro yakaipa.


Pharmacogenetic bvunzo dzinongowanikwa chete kune yakashomeka nhamba yemishonga. Pazasi pane mimwe yemishonga nemajini anogona kuyedzwa. (Mazita eGene anowanzo kupihwa mutsamba nenhamba.)

MushongaMajini
Warfarin: ropa rakaondaCYP2C9 uye VKORC1
Plavix, ropa rakaondaCYP2C19
Mishonga yekudzvinyirira, mishonga yekufa pfariCYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A / C
Tamoxifen, kurapwa kwekenza yemazamuCYPD6
AntipsychoticDRD3, CYP2D6, CYP2C19, CYP1A2
Kurapa kwekucherechedza kushomeka kusagadzikanaD4D4
Carbamazepine, kurapwa kwechirwereHLA-B 1502
Abacavir, kurapwa kweHIVHLA-B 5701
OpioidOPRM1
Statins, mishonga inorapa yakakwira cholesterolSLCO1B1
Marapirwo ehudiki leukemia uye zvimwe autoimmune kusagadzikanaTMPT


Chii chinoitika panguva yekuedzwa kwemakemakemikari?

Kuedzwa kunowanzoitwa paropa kana mate.


Kuongororwa ropa, nyanzvi yehutano anotora muyero weropa kubva mutsinga iri muruoko rwako, achishandisa tsono diki. Mushure mekunge tsono yaiswa, kashoma reropa kanounganidzwa muthubhu yekuyedza kana muhombodo. Unogona kunzwa kakuruma kana tsono ichipinda kana kubuda. Izvi zvinowanzotora maminetsi asingasviki mashanu.

Kweyedzo yemate, Kumbira mupi wako wezvehutano kuti akupe rairo yekuti ungape sei muyenzaniso wako.

Ndichafanira here kuita chero chinhu kugadzirira bvunzo?

Kazhinji haudi chero gadziriro yakakosha yekuongororwa ropa. Kana iwe urikutora bvunzo yemate, iwe haufanire kudya, kunwa, kana kuputa kwemaminitsi makumi matatu pamberi pebvunzo.

Pane here njodzi kune bvunzo?

Pane njodzi shoma yekuongororwa ropa. Unogona kunge uine marwadzo mashoma kana kupwanya panzvimbo yakaiswa tsono, asi zviratidzo zvizhinji zvinokurumidza kupera.

Iko hakuna njodzi yekuve nekuongororwa kwemate.

Zvinorevei mhedzisiro yacho?

Kana iwe wakaedzwa usati watanga kurapwa, iyo bvunzo inogona kuratidza kana mushonga ungangove unoshanda uye / kana kana iwe uri panjodzi yemhedzisiro mhedzisiro. Dzimwe bvunzo, senge dziya dzemamwe madhiragi anorapa pfari neHIV, dzinogona kuratidza kuti uri panjodzi yekukanganisa hupenyu. Kana zvirizvo, mupi wako achaedza kutsvaga imwe nzira yekurapa.


Kuyedza kunoitika usati uye paunenge uri pakurapwa kunogona kubatsira mupi wako wezvehutano kuona muyero wakakodzera.

Kana iwe uine mibvunzo nezve mhedzisiro yako, taura nemupi wako wezvehutano.

Dzidza zvakawanda nezve bvunzo dzemarabhoritari, mareferenzi masosi, uye mhinduro dzekunzwisisa

Pane chimwe chinhu here chandinofanira kuziva nezve pharmacogenetic kuyedzwa?

Pharmacogenetic kuyedzwa kunongoshandiswa chete kuwana mhinduro yemunhu kune yakatarwa mushonga. Haisi chinhu chakafanana nekuongororwa kwemajini. Mazhinji mageneral test anoshandiswa kubatsira kuongorora zvirwere kana njodzi ingangoita yechirwere, kuziva hukama hwemhuri, kana kuona mumwe munhu mukuferefetwa kwematsotsi.

Zvinyorwa

  1. Hefti E, Blanco J. Kudhizaina Pharmacogenomic Kuedza neazvino Maitiro Ekushandisa Terminology (CPT) Makodhi, Kuongorora kwekare uye kwazvino Maitiro. J AHIMA [Indaneti]. 2016 Jan [yataurwa 2018 Jun 1]; 87 (1): 56–9. Inowanikwa kubva: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
  2. Lab Kuedza Pamhepo [Internet]. Washington DC: American Association yeKiriniki Chemistry; c2001–2018. Pharmacogenetic Miedzo; [yakagadziridzwa 2018 Jun 1; yakataurwa 2018 Jun 1]; [angangoita maviri skrini. Inowanikwa kubva ku: https://labtestsonline.org/tests/pharmacogenetic-tests
  3. Lab Kuedza Pamhepo [Internet]. Washington DC: American Association yeKiriniki Chemistry; c2001–2018. Izvo Zvese zveGenetic Kuedza; [yakagadziridzwa 2017 Nov 6; yakataurwa 2018 Jun 1]; [angangoita maviri skrini. Inowanikwa kubva ku: https://labtestsonline.org/articles/genetic-testing?start=4
  4. Mayo Clinic: Center yeMunhu Akasarudzika Mushonga [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1998–2018. Kuongorora Zvinodhaka-Gene; [yakataurwa 2018 Jun 1]; [angangoita matatu skrini. Inowanikwa kubva: http://mayoresearch.mayo.edu/center-for-individualized-medicine/drug-gene-testing.asp
  5. Mayo Clinic: Center yeMunhu Akasarudzika Mushonga [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab Bvunzo; [yakataurwa 2018 Jun 1]; [angangoita mashanu skrini.Inowanikwa kubva: http://mayoresearch.mayo.edu/center-for-individualized-medicine/cyp2d6-tamoxifen.asp
  6. Mayo Clinic: Center yeMunhu Akasarudzika Mushonga [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1998–2018. HLA-B 1502 / Carbamazepine Pharmacogenomic Lab Bvunzo; [yakataurwa 2018 Jun 1]; [angangoita mana skrini. Inowanikwa kubva: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab1502-carbamazephine.asp
  7. Mayo Clinic: Center yeMunhu Akasarudzika Mushonga [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1998–2018. HLA-B 5701 / Abacavir Pharmacogenomic Lab Bvunzo; [yakataurwa 2018 Jun 1]; [angangoita mana skrini. Inowanikwa kubva: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab5701-abacavir.asp
  8. Mayo Clinic: Mayo Medical Laboratories [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1995–2018. Bvunzo ID: PGXFP: Inotarisisa Pharmacogenomics Panel: Specimen; [yakataurwa 2018 Jun 1]; [angangoita matatu skrini. Inowanikwa kubva ku: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
  9. National Cancer Institute [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. NCI Duramazwi reMitemo yeCancer: geni; [yakataurwa 2018 Jun 1]; [angangoita matatu skrini. Inowanikwa kubva: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
  10. National Mwoyo, Mapapu, uye Ropa Institute [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. Kuedzwa kweropa; [yakataurwa 2018 Jun 1]; [angangoita matatu skrini. Inowanikwa kubva: https://www.nhlbi.nih.gov/health-topics/blood-tests
  11. NIH National Institute yeGeneral Medical Sayenzi [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. Pharmacogenomics; [yakagadziridzwa 2017 Oct; yakataurwa 2018 Jun 1]; [angangoita mana skrini. Inowanikwa kubva: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
  12. NIH U.S. National Raibhurari yeMishonga: Genetics Kumba Referensi [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. Chii chinonzi pharmacogenomics ?; 2018 Chivabvu 29 [yataurwa 2018 Jun 1]; [angangoita mana skrini. Inowanikwa kubva: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
  13. UF Hutano: Yunivhesiti yeFlorida Hutano [Internet]. Yunivhesiti yeFlorida; c2018. Majini ako anofurira sei mishonga yakakunakira iwe; 2016 Jan 11 [yakagadziridzwa 2018 Jun 1; yakataurwa 2018 Jun 1]; [angangoita maviri skrini. Inowanikwa kubva: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are-right-you
  14. UW Hutano Hupenyu hweMhuri Yevana Chipatara [Internet]. Madison (WI): Yunivhesiti yeWisconsin Zvipatara uye Makiriniki Chiremera; c2018. Hutano hwevana: Pharmacogenomics; [yakataurwa 2018 Jun 1]; [angangoita mana skrini. Inowanikwa kubva: https://www.uwhealthkids.org/kidshealth/en/parents/pharmacogenomics.html/

Ruzivo ruri pane ino saiti harufanire kushandiswa sekutsiva kwehunyanzvi kurapwa kana kurairwa. Bata mupi wehutano kana iwe uine mibvunzo nezve hutano hwako.

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