Prenatal Cell-Mahara DNA Kuongorora

Zvemukati

• Chii chinonzi prenatal cell-isina DNA (cfDNA) kuongorora?
• Chii chinoshandiswa?
• Nei ini ndichida prenatal cfDNA kuongorora?
• Chii chinoitika panguva yekubata prenatal cfDNA kuongorora?
• Ndichafanira here kuita chero chinhu kugadzirira bvunzo iyi?
• Pane here njodzi kune bvunzo?
• Zvinorevei mhedzisiro yacho?
• Pane chimwe chinhu here chandinofanira kuziva nezve prenatal cfDNA kuongorora?
• Zvinyorwa

Chii chinonzi prenatal cell-isina DNA (cfDNA) kuongorora?

Prenatal cell-isina DNA (cfDNA) kuongororwa kuongororwa kweropa kune vakadzi vane nhumbu. Munguva yepamuviri, imwe yeDNA yemwana asati aberekwa inotenderera muropa raamai. A cfDNA kuongorora kunoongorora iyi DNA kuti izive kana mwana angangoita Down syndrome kana chimwe chirwere chinokonzerwa netrisomy.

A trisomy chirwere chema chromosomes. Chromosomes ndiwo maseru emasero ako ane magene ako. Magene zvikamu zveDNA zvakapfuudzwa kubva kuna mai nababa vako. Ivo vanotakura ruzivo rwunotarisa hunhu hwako hwakasarudzika, senge kukwirira uye ruvara rwemaziso.

• Vanhu vanowanzove nemakromosomes makumi mana nematanhatu, akapatsanurwa kuita makumi maviri nematatu, mune rimwe sero.
• Kana rimwe remaviri aya riine kopi yekuwedzera yekromosomu, inonzi trisomy. A trisomy inokonzeresa shanduko munzira iyo muviri nehuropi zvinokura.
• Mu Down syndrome, pane imwezve kopi yekromosomu 21. Izvi zvinozivikanwawo sekuti trisomy 21. Down syndrome ndiyo inonyanya kuzivikanwa nechromosome disorder muUnited States.
• Zvimwe zvinokanganisa trisomy zvinosanganisira Edwards syndrome (trisomy 18), uko kune imwe kopi yechromosome 18, uye Patau syndrome (trisomy 13), uko kune imwe kopi yekromosome 13. Zvirwere izvi hazviwanzo asi zvakakomba kupfuura Down syndrome. Vazhinji vacheche vane trisomy 18 kana trisomy 13 vanofa mukati megore rekutanga rehupenyu.

Kuongorora kwe cfDNA kune njodzi shoma kwauri uye kumwana wako, asi haigone kukuudza chokwadi kana mwana wako aine chirwere chromosome. Mutapi wako wezvehutano anoda kuraira mimwe bvunzo kuti asimbise kana kutonga kunze kwekuongororwa.

Mamwe mazita: fetal-isina fetus DNA, cffDNA, isina-invasive prenatal test, NIPT

Chii chinoshandiswa?

A cfDNA kuongorora kunowanzo shandiswa kuratidza kana mwana wako asati aberekwa ane njodzi yakawedzera yeimwe yeanotevera echromosome matambudziko:

• Down syndrome (trisomy 21)
• Edwards syndrome (trisomy 18)
• Patau chirwere (trisomy 13)

Kuongorora kwacho kunogona zvakare kushandiswa ku:

• Sarudza jena remwana (bonde). Izvi zvinogona kuitwa kana iyo ultrasound ichiratidza kuti nhengo dzevacheche hadzisi pachena murume kana mukadzi. Izvi zvinogona kukonzerwa nekusagadzikana kwemakromosomes ebonde.
• Tarisa Rh yeropa mhando. Rh ipuroteni inowanikwa pamasero matsvuku eropa. Kana iwe uine protein, iwe unofungidzirwa Rh yakanaka. Ukasadaro, uri Rh negative. Kana iwe uri Rh negative uye mwana wako asati aberekwa ari Rh positive, immune system yako inogona kurwisa masero eropa emwana wako. Kana iwe ukaona kuti uri Rh negative pakutanga kwepamuviri, unogona kutora mishonga kuchengetedza mwana wako kubva kumatambudziko ane ngozi.

Kuongorora kwe cfDNA kunogona kuitwa kutanga svondo regumi rekuzvitakura.

Nei ini ndichida prenatal cfDNA kuongorora?

Vazhinji vanopa hutano vanokurudzira kuongorora uku kune vakadzi vane nhumbu vane njodzi huru yekuve nemwana ane chirwere che chromosome. Unogona kunge uri panjodzi huru kana:

• Iwe une makore makumi matatu nemashanu kana kupfuura. Zera raamai ndiyo inonyanya kukonzera njodzi yekuva nemwana ane Down syndrome kana zvimwe zvinokanganisa trisomy. Ngozi inowedzera sezvo mukadzi achikura.
• Wakave nemumwe mwana ane chromosome kusagadzikana.
• Yako fetal ultrasound haina kutarisa zvakajairika.
• Mimwe mibairo yekuberekwa kwepabonde yakanga isiri yechinyakare.

Vamwe vanopa hutano vanokurudzira kuongorora kune vese vakadzi vane nhumbu. Izvi zvinodaro nekuti kuongororwa kwacho hakuna njodzi uye kune yakanyanya mwero yekururamisa kana ichienzaniswa nedzimwe bvunzo dzepabonde.

Iwe nemupi wako wekuchengeta hutano munofanira kukurukura kana cfDNA kuongorora kwakakukodzera.

Chii chinoitika panguva yekubata prenatal cfDNA kuongorora?

Nyanzvi yezvehutano inotora muyero weropa kubva mutsinga iri muruoko rwako, uchishandisa tsono diki. Mushure mekunge tsono yaiswa, kashoma reropa kanounganidzwa muthubhu yekuyedza kana muhombodo. Unogona kunzwa kakuruma kana tsono ichipinda kana kubuda. Izvi zvinowanzotora maminetsi asingasviki mashanu.

Ndichafanira here kuita chero chinhu kugadzirira bvunzo iyi?

Ungangoda kutaura kune chipangamazano usati waongororwa. A genetic chipangamazano inyanzvi yakadzidziswa mu genetics uye kuongororwa kwemajini. Iye kana iye anogona kutsanangura zvinogoneka mhedzisiro uye zvazvinogona kureva kwauri nemwana wako.

Pane here njodzi kune bvunzo?

Iko hakuna njodzi kumwana wako asati azvarwa uye panjodzi diki kwauri. Unogona kunge uine marwadzo mashoma kana kupwanya panzvimbo yakaiswa tsono, asi zviratidzo zvizhinji zvinokurumidza kupera.

Zvinorevei mhedzisiro yacho?

Kana mhedzisiro yako yanga isina kunaka, hazviite kuti mwana wako ave neA Down syndrome kana imwe trisomy disorder. Kana mhedzisiro yako yaive yakanaka, zvinoreva kuti pane njodzi yakawedzera yekuti mwana wako ane imwe yeaya matambudziko. Asi hazvigone kukuudza zvechokwadi kana mwana wako akabatwa. Kuti uwane imwe yakasimbiswa kuongororwa iwe unozoda mimwe bvunzo, senge amniocentesis uye chorionic villus sampling (CVS). Iyi bvunzo inowanzo kuve yakachengeteka maitiro, asi ivo vane njodzi diki yekukonzera kusununguka.

Kana iwe uine mibvunzo nezvemhedzisiro yako, taura nemupi wako wezvehutano uye / kana chipangamazano wezvechivanhu.

Dzidza zvakawanda nezve bvunzo dzemarabhoritari, mareferenzi masosi, uye mhinduro dzekunzwisisa

Pane chimwe chinhu here chandinofanira kuziva nezve prenatal cfDNA kuongorora?

cfDNA kuongororwa hakuna kujeka mumadzimai ane nhumbu yevanopfuura mwana mumwe (mapatya, vatatu, kana kupfuura).

Zvinyorwa

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Ruzivo ruri pane ino saiti harufanire kushandiswa sekutsiva kwehunyanzvi kurapwa kana kurairwa. Bata mupi wehutano kana iwe uine mibvunzo nezve hutano hwako.