9 Mibvunzo Nezve Waldenstrom Macroglobulinemia

Zvemukati

• 1. Waldenstrom macroglobulinemia inorapwa here?
• 2.Waldenstrom macroglobulinemia inogona kupinda mukuregererwa here?
• 3. Yakashoma sei Waldenstrom macroglobulinemiaemia?
• 4. Waldenstrom macroglobulinemia inofambira mberi sei?
• 5.Waldenstrom macroglobulinemia inomhanya mumhuri here?
• 6. Chii chinokonzera Waldenstrom macroglobulinemia?
• 7. Ungagare kwenguva yakareba sei naWaldenstrom macroglobulinemia?
• 8. Ko Waldenstrom macroglobulinemia metastasize?
• 9. Waldenstrom macroglobulinemia inorapwa sei?
• Kutora

Waldenstrom macroglobulinemia (WM) iri fomu isingawanzoitika yeasina-Hodgkin's lymphoma inoratidzirwa nekuwandisa kwemasero machena eropa.

Iyo inononoka kukura rudzi rwekenza yesero reropa iyo inobata vanhu vatatu kubva pavanhu miriyoni imwe muUnited States gore rega rega, sekureva kweAmerican Cancer Society.

WM inonziwo dzimwe nguva:

• Chirwere cheWaldenstrom
• lymphoplasmacytic lymphoma
• chikuru macroglobulinemia

Kana iwe uchinge waonekwa uine WM, unogona kunge uine mibvunzo yakawanda nezve chirwere. Kudzidza zvakawanda sezvaunogona nezve kenza uye kutsvaga nzira dzekurapa kunogona kukubatsira kutsungirira nemamiriro acho.

Hedzino mhinduro dzemibvunzo mipfumbamwe dzinogona kukubatsira kuti unzwisise zviri nani WM.

1. Waldenstrom macroglobulinemia inorapwa here?

WM parizvino haina mushonga unozivikanwa. Zvisinei, zvakasiyana-siyana zvekurapa zviripo kuti zvikubatsire kugadzirisa zviratidzo zvako.

Maonero evanhu vanoonekwa kuti vane WM akavandudzika pamusoro pemakore. Masayendisiti ari kuongororawo majekiseni ekubatsira kusimudzira masimba ezvirwere zvemuviri ekuramba rudzi urwu rwegomarara uye nekuvandudza marapirwo matsva.

2.Waldenstrom macroglobulinemia inogona kupinda mukuregererwa here?

Pane mukana mudiki wekuti WM inogona kupinda mukuregererwa, asi haina kujairika. Vanachiremba vakangoona kuregererwa kwakakwana kwechirwere muvanhu vashoma. Kurapa kwazvino hakudzivise kudzokazve.

Kunyange pasina dhata yakawanda pamitero yekuregererwa, kumwe kudzidza kudiki kubva muna2016 kwakawana kuti neWM yakaenda mukuregererwa kwakazara mushure mekurapwa ne "R-CHOP regimen."

Iyo R-CHOP regimen yaisanganisira kushandiswa kwe:

• rituximab
• cyclophosphamide
• vincristine
• doxorubicin
• zvideo

Vamwe makumi matatu nevatatu vakawana kuregererwa zvishoma.

Taura nachiremba wako kuti uone kana kurapwa uku, kana imwe nzira, yakakunakira iwe.

3. Yakashoma sei Waldenstrom macroglobulinemiaemia?

Vanachiremba vanoongorora vanhu chiuru kusvika chiuru nemazana mashanu muUnited States neWM gore rega rega, sekureva kweAmerican Cancer Society. Sangano reNyika reRare Disorders rinozviona sechiitiko chisingawanzoitika.

WM inokanganisa varume zvakapetwa kaviri kupfuura zvinoita vakadzi. Chirwere ichi hachiwanzoitika pakati pevanhu vatema kudarika icho chiri pavanhu vachena.

4. Waldenstrom macroglobulinemia inofambira mberi sei?

WM inowanzo fambira mberi zvishoma nezvishoma. Iyo inogadzira kuwandisa kwemamwe marudzi emasera eropa machena anonzi B lymphocyte.

Aya maseru anogadzira kuwandisa kwechirwere chinonzi immunoglobulin M (IgM), icho chinokonzeresa kuwedzerwa kweropa mamiriro anonzi hyperviscosity. Izvi zvinoita kuti zviomere nhengo dzako uye matukhu kuti zvishande nemazvo.

Kuwedzeredza kweB lymphocyte kunogona kusiya kamuri mupfupa remapfupa emasero eropa ane hutano. Iwe unogona kukura anemia kana yako tsvuku masero eropa kuverenga kudonha zvakaderera zvakanyanya.

Kushaikwa kwemasero eropa akajairwa kunogona kuita kuti zviomere muviri wako kurwisa mamwe marudzi ehutachiona. Maplatelet ako anogona zvakare kudonha, izvo zvinogona kutungamira mukubuda ropa nekupwanya.

Vamwe vanhu havawani zviratidzo zvemakore akati wandei mushure mekuongororwa.

Zviratidzo zvekutanga zvinosanganisira kuneta uye kushoma simba semhedzisiro yeanemia. Iwe unogona zvakare kuve nekugunun'una muminwe yako nezvigunwe uye kubuda ropa mumhuno nemumatadza.

WM inogona kupedzisira yakanganisa nhengo, zvichikonzera kuzvimba muchiropa, spleen, uye lymph node. Hyperviscosity kubva kuchirwere ichi inogona zvakare kutungamira mukusajeka kwekuona kana matambudziko neropa kuyerera kune iyo retina.

Gomarara rinogona kupedzisira rakonzera sitiroko-kunge zviratidzo nekuda kwekutenderera kweropa kuenda kuuropi, pamwe nemoyo nenyaya yeitsvo.

5.Waldenstrom macroglobulinemia inomhanya mumhuri here?

Masayendisiti achiri kudzidza WM, asi ivo vanotenda kuti majini anogarwa nhaka anogona kuwedzera mikana yevamwe yekuvandudza chirwere ichi.

Vanenge makumi maviri muzana muzana yevanhu vane rudzi urwu rwegomarara vane hukama hwepedyo nemumwe munhu ane WM kana chimwe chirwere chinokonzeresa zvisina kujairika B maseru.

Vazhinji vanhu vanoonekwa kuti vane WM havana nhoroondo yemhuri yechirwere ichi. Zvinowanzoitika semhedzisiro yesero shanduko, idzo dzisina kugarwa nhaka, muhupenyu hwese hwemunhu.

6. Chii chinokonzera Waldenstrom macroglobulinemia?

Masayendisiti haasati ataura chaizvo zvinokonzeresa WM. Humbowo hunoratidza kuti musanganiswa wemajini, zvakatipoteredza, uye hutachiona muhupenyu hwese hwemumwe munhu zvinogona kutungamira mukukura kwechirwere.

Kuchinja kwemajini MYD88 kunoitika munenge makumi mapfumbamwe muzana muzana yevanhu vane Waldenstrom macroglobulinemiaemia, sekureva kweInternational Waldenstrom's Macroglobulinemia Foundation (IWMF).

Kumwe kutsvagurudza kwakawana kubatana pakati pechirwere cheshuga C uye WM mune vamwe (asi kwete vese) vanhu vane chirwere.

Kujekesa kune zvinhu mumatehwe, rabha, zvinonyungudika, dhayi, uye pendi zvinogona zvakare kuve chinhu mune zvimwe zviitiko zveWM. Tsvagiridzo yezvinokonzera WM iri kuenderera mberi.

7. Ungagare kwenguva yakareba sei naWaldenstrom macroglobulinemia?

Ongororo dzichangobva kuitika dzinoratidza kuti hafu yevanhu vane WM vanotarisirwa kunge vari vapenyu kwemakore gumi nemana kusvika gumi nematanhatu mushure mekuongororwa kwavo, sekureva kweIWMF.

Maonero ako ega anogona kusiyana zvichienderana ne:

• zera rako
• hutano hwakazara
• kuti chirwere chinokurumidza sei

Kusiyana nemamwe marudzi ekenza, WM haina kuongororwa muzvikamu. Pane kudaro, vanachiremba vanoshandisa iyo International Prognostic Scoring System yeWaldenstrom Macroglobulinemia (ISSWM) kuongorora maonero ako.

Iyi sisitimu inofunga nezve akasiyana zvinhu, kusanganisira yako:

• zera
• huwandu hweropa hemoglobin
• platelet kuverenga
• beta-2 microglobulin chikamu
• monoclonal IgM nhanho

Zvichienderana nezvakawanda zvako zvezviitiko izvi zvine njodzi, chiremba wako anogona kukuisa muboka rakaderera-, repakati-, kana rine njodzi, iro rinogona kukubatsira kuti unzwisise maonero ako.

Makore mashanu ekupona kwevanhu vari muboka rine njodzi yakaderera i87 muzana, iro repakati-panjodzi boka i68 muzana, uye rine njodzi huru zvikamu makumi matatu nezvitatu muzana, sekureva kweAmerican Cancer Society.

Aya manhamba akavakirwa pane data kubva kuvanhu mazana matanhatu vakawanikwa vaine WM uye vakarapwa pamberi paNdira 2002.

Mishonga mitsva inogona kupa tariro yakawanda.

8. Ko Waldenstrom macroglobulinemia metastasize?

Ehe. WM inokanganisa lymphatic tishu, iyo inowanikwa munzvimbo zhinji dzemuviri. Panguva iyo munhu anoonekwa aine chirwere ichi, inogona kutowanikwa muropa nemongo wemabhonzo.

Iyo inogona ipapo kupararira kune iyo lymph node, chiropa, uye spleen. Muzviitiko zvisingawanzoitika, WM inogona zvakare kusanganisa mudumbu, gland yegland, ganda, mapapu uye ura.

9. Waldenstrom macroglobulinemia inorapwa sei?

Kurapa kweWM kunosiyana kubva pamunhu kuenda kumunhu uye kazhinji hakutangi kusvikira iwe waona zviratidzo kubva kuchirwere. Vamwe vanhu vanogona kusada kurapwa kusvika makore mashoma mushure mekuonekwa kwavo.

Chiremba wako anogona kukurudzira kutanga kurapwa kana mamwe mamiriro anokonzerwa nekenza aripo, kusanganisira:

• hyperviscosity chirwere
• kupererwa neropa
• kukuvara kwetsinga
• matambudziko enhengo
• amyloidosis
• cryoglobulins

Mhando dzakasiyana dzekurapa dziripo kuti dzibatsire iwe kubata zviratidzo. Kurapa kwakajairika kweWM kunosanganisira:

• plasmapheresis
• chemotherapy
• yakanangwa kurapwa
• immunotherapy

Muzviitiko zvisingawanzoitika, chiremba wako anogona kukurudzira marapirwo mashoma, akadai se:

• kubviswa kwepleen
• stem sero kuisazve
• radiation kurapwa

Kutora

Kuonekwa uine kenza isingawanzo kufanana neWM kunogona kuva chiitiko chinotyisa.

Nekudaro, kuwana ruzivo rwekubatsira iwe kuti unzwisise zvirinani mamiriro ako uye nzira dzekurapa, zvinogona kukubatsira mukunzwa kuve nechivimbo nezvemaonero ako.