Sickle Cell Anemia Inogara Sei?

Zvemukati

• Ndeupi musiyano uripo pakati peinonyanya uye yakawandisa geni?
• Iko sickle cell anemia autosomal kana bonde-yakabatana?
• Ndingaziva sei kana ndikapfuudza geni kumwana wangu?
• Ndinoziva sei kuti ndiri mutakuri?
• Chinokosha

Chii chinonzi sickle cell anemia?

Sickle cell anemia chiitiko chemajini chiripo kubva pakuberekwa. Mazhinji majini mamiriro anokonzerwa neakachinjika kana akachinja majini kubva kuna amai vako, baba, kana vese vabereki.

Vanhu vane sickle cell anemia vane masero matsvuku eropa ayo akaumbwa secrescent kana jeko. Ichi chimiro chisina kujairika chiri nekuda kwekuchinja mune iyo hemoglobin geni. Hemoglobin ndiyo mamorekuru ari pamasero matsvuku eropa anovabvumira kuendesa okisijeni kumatumbu mumuviri wako wese.

Masero matsvuku eropa akaita sekere anogona kutungamira kumatambudziko akasiyana siyana. Nekuda kwechimiro chavo chisina kujairika, vanogona kunamatira mukati memidzi yeropa, zvichitungamira kuzviratidzo zvinorwadza. Pamusoro pezvo, masero ejeko anofa nekukurumidza kupfuura chaiwo masero matsvuku eropa, ayo anogona kutungamira mukushaya ropa.

Mamwe, asi kwete ese, majini mamiriro anogona kugarwa nhaka kubva kune mumwe kana vaviri vabereki. Sickle cell anemia ndeimwe yeaya mamiriro. Yayo nhaka yemhando ndeyokuzvidzora kuwedzeredza. Zvinorevei mazwi aya? Chaizvoizvo sickle cell anemia inopfuudzwa kubva kumubereki kuenda kumwana? Verenga pamusoro kuti udzidze zvimwe.

Ndeupi musiyano uripo pakati peinonyanya uye yakawandisa geni?

Geneticists vanoshandisa mazwi akakosha uye akawandisa kutsanangura mukana weimwe hunhu huri kupfuudzwa kuchizvarwa chinotevera.

Iwe une maviri makopi eumwe neumwe wemajini ako - imwe kubva kuna amai vako uye imwe kubva kuna baba vako. Imwe neimwe kopi yegene inonzi allele. Iwe unogona kugashira akakwirira allele kubva kumubereki wega wega, kudzikisira kwakadzikira kubva kune mumwe mubereki, kana mumwe weumwe neumwe.

Dzakakura alleles kazhinji inodarika akawandisa alleles, ndosaka zita ravo. Semuenzaniso, kana iwe ukagara nhaka yakawandisa kubva kuna baba vako uye yakakurisa kubva kuna amai vako, iwe unowanzo ratidza hunhu hwakabatana neakanyanya allele.

Iyo jeko cell cell anemia hunhu inowanikwa pane yakawandisa allele yehemoglobin geni. Izvi zvinoreva kuti iwe unofanirwa kuve nemaviri makopi ezvakawanda zvekare - imwe kubva kuna amai vako uye imwe kubva kuna baba vako - kuti uve nemamiriro acho.

Vanhu vane imwechete yepamusoro uye imwe yakawandisa kopi yeallele havazove nejeko cell anemia.

Iko sickle cell anemia autosomal kana bonde-yakabatana?

Autosomal uye pabonde-zvine hukama zvinongedzera kuchromosome iyo allele iripo.

Sero rega rega remuviri wako rinowanzova nemapara makumi maviri nematatu emakromosomes. Kunze kwevaviri vaviri, imwe chromosome inogarwa kubva kuna amai vako uye imwe kubva kuna baba vako.

Iwo ekutanga makumi maviri nemaviri ema chromosomes anonzi ma autosomes uye akafanana pakati pevarume nevakadzi.

Iwo maviri ekupedzisira echromosomes anonzi echikadzi echromosomes. Aya ma chromosomes anosiyana pakati pevakadzi. Kana iwe uri mukadzi, iwe wakagamuchira X chromosome kubva kuna amai vako uye X chromosome kubva kuna baba vako. Kana iwe uri murume, iwe wakagamuchira X chromosome kubva kuna amai vako uye Y chromosome kubva kuna baba vako.

Mimwe geni mamiriro ezvinhu ane hukama hwepabonde, zvichireva kuti izvo zvese zviripo pane X kana Y chromosome yebonde. Zvimwe ndezvomuchadenga, zvichireva kuti zvisaririra zviripo pane rimwe remota.

Iyo sickle cell anemia allele ndeye autosomal, zvichireva kuti inogona kuwanikwa pane imwe yemamwe mairi maviri maviri echromosomes, asi kwete pane X kana Y chromosome.

Ndingaziva sei kana ndikapfuudza geni kumwana wangu?

Kuti uve nejeko cell anemia, iwe unofanirwa kuve nemaviri makopi eakawandisa masero esero akarara. Asi ko avo vane kopi imwe chete? Vanhu ava vanozivikanwa sevatakuri. Ivo vanonzi vane jeko cell trait, asi kwete jeko cell anemia.

Vatakuri vane imwechete yepamusoro uye kamwe yakadzora allele. Rangarira, chirevo chakakurumbira chinowanzo kudarika chinodzikisira, saka vatakuri kazhinji havana chero chiratidzo chemamiriro acho. Asi ivo vanokwanisa kupfuudza kukwirisa kwakanyanya kuenda kuvana vavo.

Heano mashoma emuenzaniso mienzaniso kuratidza kuti izvi zvingaitika sei:

• Muenzaniso 1. Hakuna mubereki ane iyo yakawandisa siketi masero allele. Hapana mumwe wevana vavo anozove nejeko cell anemia kana kuve vatakuri veiyo yakawandisa allele.
• Muenzaniso 2. Mumwe mubereki mutakuri nepo mumwe asiri. Hapana mumwe wevana vavo achange aine sickle cell anemia. Asi pane mukana we50 muzana wekuti vana vachatakura.
• Muenzaniso 3. Vabereki vaviri vatakuri. Pane mukana makumi maviri neshanu muzana wekuti vana vavo vagamuchire maelelic maviri, zvichikonzera sickle cell anemia. Kune zvakare mukana we50 muzana yekuti ivo vanozove mutakuri. Chekupedzisira, kune zvakare 25 muzana mukana wekuti vana vavo havazotakure allele zvachose.
• Muenzaniso 4. Mumwe mubereki haasi mutakuri, asi mumwe ane sickle cell anemia. Hapana kana mumwe wevana vavo achange aine sickle cell anemia, asi vese vanozove vatakuri.
• Muenzaniso 5. Mumwe mubereki anotakura uye mumwe ane sickle cell anemia. Pane mukana we50 muzana wekuti vana vachange vaine sickle cell anemia uye makumi mashanu muzana mukana wekuti vatakure.
• Muenzaniso 6. Vese vabereki vane sickle cell anemia. Vese vana vavo vachange vaine sickle cell anemia.

Ndinoziva sei kuti ndiri mutakuri?

Kana iwe uine nhoroondo yemhuri ye sickle cell anemia, asi iwe hauna iwe pachako, unogona kunge uri mutakuri. Kana iwe uchiziva vamwe mumhuri yako vanazvo, kana iwe usina chokwadi nezve yako nhoroondo yemhuri, bvunzo yakapusa inogona kubatsira kuona kana iwe uchitakura jeko cell allele.

Chiremba anotora muyero weropa mudiki, kazhinji kubva pamunwe weminwe, ozvitumira kurabhoritari kunoongororwa. Kana mhedzisiro yacho yagadzirira, chipangamazano anozoenda pamusoro pavo kuti akubatsire kunzwisisa njodzi yako yekuendesa vana vako.

Kana iwe ukatakura akawandisa allele, izano rakanaka kuti mumwe wako atore bvunzo futi. Uchishandisa mhedzisiro yezvose zviri zviviri zveyedzo yako, chipangamazano anokwanisa kubatsira imi mose kunzwisisa kuti sickle cell anemia inogona sei kana kuti isingakanganise chero vana venguva yemberi vauinavo pamwechete.

Chinokosha

Sickle cell anemia chiitiko chemajini chine autosomal recessive nhaka pateni. Izvi zvinoreva kuti mamiriro acho haana kubatana nema chromosomes ebonde. Mumwe munhu anofanirwa kugashira makopi maviri eacessess allele kuitira kuti ave nemamiriro acho. Vanhu vane imwechete yepamusoro uye imwe yakanyanyisa allele vanonzi vatakuri.

Kune akawanda akasiyana nhaka mamiriro ezve sickle cell anemia, zvinoenderana nemageneti evabereki vese. Kana iwe uchinetsekana kuti iwe kana mumwe wako munogona kupfuudza izvo zvisaririra kana mamiriro kune vana venyu, nyore genetiki bvunzo inogona kukubatsira iwe kufamba munzira dzese dzinogona kuitika.