Chii chinonzi Vogt-Koyanagi-Harada syndrome
Zvemukati
Vogt-Koyanagi-Harada Syndrome chirwere chisingawanzo chinobata matishu ane melanocytes, senge maziso, epakati etsinga system, nzeve uye ganda, zvichikonzera kuzvimba muziso reziso, rinowanzo sangana nedambudziko redermatological uye kunzwa.
Ichi chirwere chinowanzoitika kune vechidiki vechidiki vari pakati pemakore makumi maviri nemakumi mana, nevakadzi vari ivo vakanyanya kubatwa. Kurapa kunosanganisira kuitisa kwecorticosteroids uye maunomomodulators.
Chii chinokonzera
Chikonzero chechirwere ichi hachisati chazivikanwa, asi zvinofungidzirwa kuti ndicho chirwere chemuviri, umo mune hukasha pamusoro pemelanocyte, zvichikurudzira kuita kwekuputira nehukuru hweT lymphocyte.
Zviratidzo zvinogona kuitika
Zviratidzo zveiyi syndrome zvinoenderana nedanho iwe rauri:
Chikamu cheprodromal
Padanho rino, systemic zviratidzo zvakafanana nezviratidzo zvehururu-zvinoonekwa, zvichiperekedzwa nezviratidzo zvetsinga zvinongogara mazuva mashoma chete. Zviratidzo zvakajairika fivha, kutemwa nemusoro, meningism, kusvotwa, dzungu, kurwadziwa kwakakomberedza maziso, tinnitus, kuwanda kwemhasuru kushaya simba, kuoma mitezo kune rumwe rutivi rwemuviri, kunetseka kutaura mazwi nenzira kwayo kana kuona mutauro, photophobia, kubvarura, ganda uye ganda hypersensitivity.
Uveitis nhanho
Padanho rino, kuratidzwa kwemaziso kunotungamira, senge kuzvimba kweti retina, kuderera kwemaonero uye kupedzisira kune dhijitari. Vamwe vanhu vanogona zvakare kunzwa zviratidzo zvekunzwa senge tinnitus, kurwadziwa uye kusagadzikana munzeve.
Chisingaperi nhanho
Mune ino nhanho, ocular uye dermatological zviratidzo zvinoratidzwa, senge vitiligo, depigmentation ye eyelashes, tsiye, dzinogona kugara kubva kumwedzi kusvika kumakore. Vitiligo inowanzo kuenzanisirwa pamusoro pemusoro, kumeso uye trunk, uye inogona kuve yechigarire.
Kudzokorora danho
Padanho rino vanhu vanogona kukudziridza kusingaperi kuzvimba kwetina, cataract, glaucoma, choroidal neovascularization uye subretinal fibrosis.
Kurapwa kunoitwa sei
Kurapa kunosanganisira kuitiswa kwemadosi epamusoro ecorticosteroids senge prednisone kana prednisolone, kunyanya muchikamu chakakomba chechirwere, kwemwedzi mitanhatu. Mushonga uyu unogona kukonzeresa kushomeka uye kusagadzikana kwechiropa uye mune izvi zviitiko zvinokwanisika kusarudza kushandiswa kwe betamethasone kana dexamethasone.
Mune vanhu mune avo mhedzisiro yemigumisiro yecorticosteroids inoita kuti vashandise mune mashoma madhizaini asingagadzirisike, immunomodulators senge cyclosporine A, methotrexate, azathioprine, tacrolimus kana adalimumab inogona kushandiswa, iyo yakashandiswa nemhedzisiro yakanaka.
Mune zviitiko zvekurwisa corticosteroids uye nevanhu vasingateereri kurapwa kwemunomodulatory, intravenous immunoglobulin inogona kushandiswa.
Iva Nechokwadi Chekutarisa
Digitalis chepfu
