Steroid yekurapa kweRheumatoid Arthritis

Zvemukati

• Mhedziso
• Ruzhinji ruzivo nezve steroids yeRA
• Oral steroids yeRA
• Chipimo chemushonga
• Steroid majekiseni eRA
• Chipimo chemushonga
• Misoroo steroids yeRA
• Ngozi dzekushandisa steroids yeRA
• Zvikanganiso zveSteroids
• Kutora

Mhedziso

Rheumatoid arthritis (RA) chirwere chisingaperi chinoita kuzvimba chinoita kuti majoini madiki emaoko ako netsoka zvinorwadza, kuzvimba, uye kuomarara. Ndicho chirwere chinofambira mberi chisati chave nemushonga. Pasina kurapwa, RA inogona kutungamira mukubatana kuparadzwa uye kuremara.

Kutanga kuongororwa uye kurapwa kunoderedza zviratidzo uye kunatsiridza hupenyu hwako neRA. Kurapa kunoenderana nemamiriro ako ega. Zvirongwa zvekurapa zvinowanzo sanganisira chirwere-chinogadzirisa antirheumatic madhiragi (DMARDs) akasanganiswa neasisteroidal anti-anogumbura zvinodhaka (NSAIDs), uye yakaderera-dose steroid. Dzimwe nzira dzokurapa dziripo zvakare, kusanganisira kushandiswa kwemishonga inorwisa mabhakitiriya minocycline.

Ngatitorei zvakanyanya nezveiyo inobata steroids pakurapa RA.

Ruzhinji ruzivo nezve steroids yeRA

Steroid zvine hunyanzvi inonzi corticosteroids kana glucocorticoids. Iwo ekugadzirwa ekugadzirwa akafanana necortisol, hormone yako adrenal glands inogadzira zvakasikwa. Kusvikira makore makumi maviri apfuura, steroids yaive yakajairwa kurapwa kweRA.

Asi izvi zviyero zvakashanduka sezvo zvinokuvadza zvema steroids zvakazozivikanwa uye semhando nyowani dzemishonga dzakagadzirwa. Iyo yazvino RA nhungamiro yeAmerican College yeRheumatology ikozvino kuraira vanachiremba kuti vashandise yakaderera inogoneka huwandu hwesteroid kwenguva pfupi.

Steroid inogona kutorwa nemuromo, nejekiseni, kana kuiswa pamusoro.

Oral steroids yeRA

Oral steroids inouya mupiritsi, capsule, kana fomu remvura. Ivo vanobatsira kudzikisa mwero wekuzvimba mumuviri wako unoita majoini ako kuzvimba, kuomarara, uye kurwadza. Ivo zvakare vanobatsira kudzora yako autoimmune system kudzvinyirira flare-ups. Pane humwe humbowo hwekuti steroids inoderedza kuora kwemapfupa.

Mhando dzakajairika dzeSteroids dzinoshandiswa RA dzinosanganisira:

• prednisone (Deltasone, Sterapred, Liquid Yakafanotaurwa)
• hydrocortisone (Cortef, A-Hydrocort)
• kuuchi
• dexamethasone (Dexpak Taperpak, Decadron, Hexadrol)
• methylprednisolone (Depo-Medrol, Medrol, Methacort, Depopred, Predacorten)
• chemura
• dexamethasone (Decadron)
• betamethasone

Prednisone ndiyo inowanzo shandiswa steroid muRA kurapwa.

Chipimo chemushonga

Iyo yakaderera-dosi yemuromo steroids inogona kupihwa yekutanga RA, pamwe neDMARDs kana zvimwe zvinodhaka. Izvi zvinodaro nekuti maDMARD anotora masvondo masere kusvika gumi nemasere kuratidza zvawanikwa. Asi steroid inoshanda nekukurumidza, uye iwe uchaona maitiro avo mumazuva mashoma. Steroid dzimwe nguva inonzi "kurapwa kwebhiriji."

Mushure mekunge mimwe mishonga yashanda, zvakakosha kubvisa ma steroids. Izvi zvinowanzoitwa zvishoma nezvishoma, mukuwedzera kwe. Iyo tapering inobatsira kudzivirira kubvisa zviratidzo.

Iyo yakajairwa dosi ye prednisone ndeye 5 kusvika 10 mg zuva nezuva. Zvinokurudzirwa kuti iwe usatora zvinopfuura gumi mg pazuva re prednisone. Inogona kupihwa muzvikamu zviviri zveimwe neimwe.

Kazhinji, steroid inotorwa mangwanani paunomuka. Apa ndipo apo muviri wako wega steroids unove unoshanda.

Mazuva ese zvinowedzera zvecalcium () uye vhitamini D () zviri pamwe chete nesteroid.

Dosi yepamusoro yesteroid inogona kushandiswa muRA kana paine matambudziko akakomba.

Ongororo ya2005 yeRA data yakawana kuti makumi maviri kusvika makumi mana muzana yevanhu vachangoonekwa vaine RA vaishandisa steroid. Ongororo iyi yakawanawo kuti kusvika pa75 muzana yevanhu vane RA vakashandisa steroid pane imwe nguva.

Mune zvimwe zviitiko, vanhu vane yakaoma (dzimwe nguva inonzi inoremadza) RA vanova vanovimba nesteroids kwenguva refu kuitira kuti vaite mabasa ezuva nezuva.

Steroid majekiseni eRA

Steroid inogona kuiswa jekiseni rakachengeteka nachiremba wako muzvibatanidzwa nenzvimbo yakavapoterera pakurwadziwa uye kuzvimba zororo. Izvi zvinogona kuitwa iwe uchichengetedza imwe yakatarwa kurapwa kurapwa.

IAmerican College yeRheumatology inocherekedza kuti mukutanga RA, majekiseni eSteroid mumajoini anobatanidzwa zvikuru anogona kupa runyararo rwemuno uye dzimwe nguva. Ruyamuro urwu runogona kunge runoshamisa, asi harugari.

Mune zvimwe zviitiko, majekiseni e-steroid anga ari mukuderedza saizi yeRA nodules. Izvi zvinopa imwe nzira yekuvhiya.

Zvinokurudzirwa kuti majekiseni muchijoini chimwe chete asaitwe kanopfuura kamwe chete mumwedzi mitatu.

Chipimo chemushonga

Iyo steroid inowanzo shandiswa jekiseni ndeye methylprednisolone acetate (Depo-Medrol), triamcinolone hexacetonide, uye triamcinolone acetonide.

Chiremba wako anogona zvakare kushandisa anesthetic yemuno kana achikupa steroid jekiseni.

Muyero we methylprednisolone unowanzo kuve 40 kana 80 mg pamamirita. Muyero wacho unosiyana zvichienderana nehukuru hwejoinhi iri kuiswa jekiseni. Semuenzaniso, ibvi rako rinogona kuda muhombe muhombe, unosvika makumi masere. Asi gokora rako rinogona kungoda 20 mg.

Misoroo steroids yeRA

Misoro steroid, ese ari pamusoro-e-pikisheni uye mishonga yemishonga, inowanzo shandiswa nevanhu vane chirwere cheArthritis chekuzorodza kwemuno. Asi misoro steroids haina kukurudzirwa (kana kutaurwa) muAmerican College yeRheumatology RA nhungamiro.

Ngozi dzekushandisa steroids yeRA

Steroid kushandiswa muRA kurapwa kuri nekuda kwenjodzi dzakanyorwa dzakabatanidzwa.

Njodzi dzakakosha dzinosanganisira:

• Kumira kurova kwemoyo: Ongororo ya2013 yevanhu vakawanikwa vaine RA uye vachitora steroid vakawana 68 muzana yakawedzera njodzi yekurwadziwa kwemoyo. Chidzidzo ichi chaisanganisira vanhu zviuru zvisere nemazana matatu ane makumi matatu nesere nemakumi matatu neshanu vakaonekwa vaine RA pakati pa1997 na2006. Imwe neimwe 5 mg pazuva inowedzera muyero yakawedzerwa panjodzi.
• Osteoporosis: inofambiswa neyekureba-refu steroid kushandiswa ndiyo njodzi huru.
• Kufa: Zvimwe zvidzidzo zvekucherechedza zvinoratidza kuti kufa kunogona kuwedzerwa nekushandisa steroid.
• Kurwara
• Chirwere cheshuga

Njodzi dzinowedzera nekushandisa kwenguva refu uye madosi epamusoro.

Zvikanganiso zveSteroids

Mhedzisiro kubva kuSteroid kushandiswa muRA kurapwa inosanganisira:

• njodzi yakawedzera yehutachiona kana hutachiona hutachiona
• kurema kuwedzera
• kumeso kwakatenderedzwa, kunonziwo "kumeso kwemwedzi"
• kuwedzerwa shuga yeropa
• BP
• kushungurudzika kwemanzwiro, kusanganisira kushushikana uye kushushikana
• kushaya hope
• kuzvimba gumbo
• kupwanya kuri nyore
• kuwanda kwakanyanya kwekutsemuka
• adrenal kusakwana
• yakadzora mapfupa emaminetsi emwedzi mishanu mushure mekutapa kwe10 mg prednisone

Steroid jekiseni mhedzisiro isingawanzoitika uye kazhinji kwenguva pfupi. Izvi zvinosanganisira:

• kutsamwa kweganda
• neutachiona
• kuonda kweganda

Tarisa nachiremba wako kana mhedzisiro iri kunetsa kana kuitika kamwe kamwe. Chengetedza shuga yako yeropa kana uine chirwere cheshuga.

Kutora

Steroid mune yakaderera madhizaini inogona kuve chikamu chehurongwa hwekurapa hweRA kubvisa zviratidzo. Ivo vanoshanda nekukurumidza kudzora kuzvimba uye kurwadziwa. Asi iwe unofanirwa kunyatso tarisa njodzi dzinozivikanwa dzekushandisa steroid, kunyangwe pane yakaderera dosi.

Verenga pamusoro pese mukana wekurapa, kusanganisira biologics uye iyo antibiotic minocycline. Yera zvayakanakira nezvazviri pakurapa kwega kwega uye kusanganiswa kwemishonga.Kurukurai marongero angangoita ekurapa nachiremba wako, uye ita shuwa kuti mibvunzo yako yese inopindurwa.

Pamusoro pazvose, RA kurapwa kunoda kuti iwe uve anoshanda.