Primary-Progressive MS (PPMS): Zviratidzo uye Kuongororwa

Zvemukati

• PPMS yakasiyana sei nedzimwe mhando dzeMS?
• Chii chinokonzera PPMS?
• Ndezvipi zviratidzo zvePPMS?
• Tsandanyama kuzvimba
• Kuneta
• Unhu / kugwinha
• Matambudziko nemaonero
• Nyaya dzine cognition
• Dzungu
• Matambudziko edundira uye ura
• Kushungurudzika
• PPMS inoonekwa sei?
• Kurapa nzira
• Outlook

Chii chinonzi PPMS?

Multiple sclerosis (MS) ndicho chirwere chakajairika cheiyo yepakati tsinga system. Inokonzerwa nemhinduro yemumuviri inoparadza iyo myelin sheath, kana kupfeka pamitsipa.

Primary progressive multiple sclerosis (PPMS) ndeimwe yemhando ina dzeMS. Aya matatu mamwe marudzi eMMS ndeaya:

• kliniki yakasarudzika chirwere (CIS)
• kudzokerazve kuregererwa (RRMS)
• kufambira mberi kwechipiri (SPMS)

PPMS ndeimwe yemhando diki diki, inokanganisa vangangoita gumi muzana yevanhu vese vanoonekwa vaine MS.

PPMS yakasiyana sei nedzimwe mhando dzeMS?

Vazhinji vanhu vanobatwa neMMS vanorwiswa zvakanyanya nezviratidzo, zvinonzi kudzokazve, uye nguva yemwedzi kana makore vasina zvishoma zviratidzo, zvinonzi kuregererwa.

PPMS yakasiyana. Hosha yacho inofambira mberi kana zviratidzo zvatanga kuoneka, saka iro zita rekutanga kufambira mberi. Panogona kunge paine nguva dzekufambira mberi uyezve nguva dzekusaita kufambira mberi kwezviratidzo uye kuremara.

Mumwe mutsauko uripo pakati pePPMS nemafomu ekudzokazve ndeekuti kunyangwe kufambira mberi kwekushanda kuchimira kwenguva pfupi, zviratidzo hazvigadzirise. Mune mafomu ekudzokazve, zviratidzo zvinogona kunyatso kuvandudza kana kudzoka padhuze nekwavaive ivo vasati vadzoka zvakare.

Mumwe mutsauko ndewekuti hapana kunyanya kuzvimba muPPMS zvichienzaniswa nemafomu ekudzokazve. Nekuda kweizvi, mazhinji emishonga inoshanda yekudzokazve mafomu haishande kune PPMS kana SPMS. Kufambira mberi kwezviratidzo kunogona kukuvadza pamusoro pemwedzi mishoma kana makore akati wandei.

PPMS inowanzoonekwa muvanhu vane makore makumi mana nemakumi mashanu. RRMS, kune rimwe divi, inowanzo kupa mune vanhu vane makore makumi maviri nemakumi matatu. PPMS inobatawo vese vanhukadzi zvakaenzana, nepo RRMS inobata vakadzi vaviri kana katatu zvakapetwa sevarume.

Chii chinokonzera PPMS?

PPMS inokonzereswa nekukanganisa tsinga kunokanganisa tsinga kubva pakutumira masaini kune mumwe nemumwe. Ese mana marudzi eSMS anosanganisira kukuvara kune inodzivirira yekupfeka (myelin) yepakati tsinga system, inonzi demyelination, pamwe nekukuvara kwenzara.

Ndezvipi zviratidzo zvePPMS?

PPMS zviratidzo zvakafanana nezviratidzo zvePSMS. Ehe, izvo zvinoitika kune mumwe munhu zvichave zvakasiyana kubva kune mumwe.

Zviratidzo zvePPMS zvinogona kusanganisira zvinotevera:

Tsandanyama kuzvimba

Kudzvinyirira kuenderera kwemamwe mhasuru kunogona kukonzera kuomarara uye kuomarara, izvo zvinogona kukanganisa kufamba. Izvi zvinogona kuita kuti zvinyanye kuomarara kufamba, shandisa masitepisi, uye kukurudzira chiitiko chako chezvese chiitiko.

Kuneta

Vanenge makumi masere muzana yeavo vane PPMS vanoona kuneta. Izvi zvinogona kukanganisa zvakanyanya hupenyu hwezuva nezuva uye kuita kuti zviome kushanda uye kupedzisa zviitiko zvenguva dzose. Vaya vanoonekwa kuti vane PPMS vanogona kuzviwana vakaneta zvikuru kubva kuzviitwa zvakapusa. Semuenzaniso, basa rekubika kudya kwemanheru rinogona kuvapedza uye rinoda kuti varare.

Unhu / kugwinha

Chimwe chiratidzo chekutanga chePPMS kudzikama kana kugwinha munzvimbo dzakasiyana dzemuviri, senge kumeso kwako, maoko, uye tsoka. Izvi zvinogona kuvharirwa kune imwe nzvimbo yemuviri wako, kana kuenda kune dzimwe nhengo.

Matambudziko nemaonero

Izvi zvinogona kusanganisira kuona kwakapetwa, kuona kwakakanganiswa, kusakwanisa kuona mavara uye kusiyana, uye kurwadziwa kana uchifambisa maziso ako.

Nyaya dzine cognition

Ipo PPMS inowanzo kukanganisa kufamba, vamwe vanhu vanogona kusangana nekudzikira kwekuziva. Izvi zvinogona kukanganisa zvakanyanya kurangarira uye kugadzirisa ruzivo, kugadzirisa matambudziko, kutarisa, uye kudzidza chero chinhu chitsva.

Dzungu

Avo vane PPMS vanogona kunge vane zvikamu zvezungu uye nehuremu hwemusoro. Vamwe vanogona kuona vertigo, kunzwa kwekuti ivo vari kutenderera uye kurasikirwa neyakaenzana.

Matambudziko edundira uye ura

Matambudziko edundira uye ura anogona kubva pakusaita kusagadzikana, kusvika pakuda kuenda nguva dzose, kuzvimbirwa. Izvi zvinogona kutungamira kumatambudziko epabonde, senge kudzikira kwekutyaira pabonde, kunetsekana kuchengetedza erection, uye kushoma kwekunzwa mukati memitezo.

Kushungurudzika

Inenge hafu yevanhu vese vane MS vachatarisana neinenge imwechete yekuora mwoyo episode. Kunyangwe zvakajairika kutsamwa kana kutsamwa pamusoro pekuremara kuri kuwedzera, aya manzwiro anochinja anowanzoenda nenguva. Clinical kushushikana, kune rumwe rutivi, haudzike uye inoda kurapwa.

PPMS inoonekwa sei?

PPMS ine zviratidzo zvakafanana kune mamwe marudzi eMMS, pamwe nemamwe matambudziko etsinga. Nekuda kweizvozvo, zvinogona kutora kusvika kumakore matatu kureba kuti uwane yakagadziriswa PPMS kuongororwa pane RRMS kuongororwa.

Kuti uwane yakagadziriswa PPMS kuongororwa, unofanirwa:

• uve negore rekuenderera mberi uchishatisa neurologic basa
• sangana nemaviri eanotevera maitiro:
  • chirwere cheuropi chinowanzoonekwa kuMMS
  • maviri kana anopfuura maronda akafanana mumuzongoza wako
  • kuvapo kwemapuroteni anonzi immunoglobulins

Chiremba wako angangoitisa bvunzo yezvekurapa uye akubvunze nezve chero zviitiko zvekare zveeurologic. Vanogona kukumbira nhengo dzemhuri kuti dzivepo, sezvo vachigona kupa kwavo zviitiko nezviratidzo zvakapfuura. Chiremba wako anozoita ongororo yepanyama, achitarisa tsinga nemhasuru.

Chiremba wako acharaira MRI scan kuti aongorore maronda muuropi uye musana. Ivo vanogona zvakare kuraira iyo yakabviswa mukana (EP) bvunzo kuti utarise mashandiro emagetsi muuropi. Pakupedzisira, chiremba wako achaita pombi yekumusana kuti atsvake zviratidzo zveMS mune yemusana mvura.

Kurapa nzira

Iko hakuna mushonga wePPMS. Mumwe mushonga, ocrelizumab (Ocrevus), unobvumidzwa PPMS pamwe nekudzokorodza mafomu eSMS. Immunosuppressants inowanzo shandiswa mukudzokazve mafomu, zvisinei, nekuti iwo anoderedza kuzvimba. PPMS haina yakawanda yekuzvimba, saka immunosuppressants inogona kusakurudzirwa seinobatsira. Kutsvagisa nezvekurapa kwakanaka kuri kuenderera.

Outlook

Kunyange pasina mushonga wePPMS, avo vanoonekwa kuti vane PPMS havafanirwe kurasa tariro. Nerubatsiro rwevanachiremba, varapi vemuviri, nyanzvi dzekutaura, uye nyanzvi mune hutano hwepfungwa, pane nzira dzekugadzirisa chirwere ichi. Izvi zvinogona kusanganisira mishonga inobatsira kubvisa zviratidzo, senge kutapudza kwemhasuru kwemasuru spasms, pamwe nekudya zvine hutano, kurovedza muviri, uye tsika yakakodzera yekurara.