Psoriasis Kurapa

Zvemukati

• Misoro yekurapa ye psoriasis
• Vitamin D zvakafanana
• Marasha tara makirimu kana mafuta ekuzora
• Mashambi shampoos
• Salicylic acid uye lactic acid
• Zvirongwa zvehurongwa zve psoriasis
• Methotrexate
• Cyclosporine
• PDE4 inhibitors
• Retinoids
• Hydroxyurea
• Immunomodulator zvinodhaka (biologics)
• Thioguanine
• Kunyoresa mazita ekushandisa zvinodhaka
  
• Phototherapy (light therapy)
• Chiedza chezuva
• UVB phototherapy
• Goeckerman kurapwa
• Excimer Laser
• Photochemotherapy, kana psoralen pamwe ultraviolet A (PUVA)
• Pulsed dhayi laser

Mhedziso

Kurapa psoriasis zvinowanzoda nzira dzakasiyana dzakasiyana. Izvi zvinogona kusanganisira shanduko yemararamiro, chikafu, Phototherapy, uye mishonga. Kurapa kunoenderana nekuoma kwezviratidzo zvako, zera rako, hutano hwako hwese, uye zvimwe zvinhu.

Iko hakuna kurapwa kwe psoriasis, saka vanachiremba vanowanzoedza nzira dzinoverengeka vasati vawana kurapwa kwakakodzera kwauri.

Kurapa sarudzo ye psoriasis kunoenderana nezvinhu zvinotevera:

• kuomarara kwe psoriasis yako
• kuti muviri wako wakanganiswa zvakadii
• yako mhando ye psoriasis
• ganda rako rinonyatsopindura sei pakurapwa kwekutanga

Mazhinji marapirwo akajairwa anoitirwa kurapa zviratidzo zvechirwere. Ivo vanoedza kunyaradza iyo inonzwika uye inopenya ganda uye kudzikisira kuputika-kumusoro. Kugara uchishandisa over-the-counter (OTC) moisturizers mushure mekugeza uye mashawa zvinogona kubatsira kuchengetedza hunyoro muganda kudzivirira kubvunda. Asi hazvingarape kuzvimba kuri pasi.

MaDermatologist anokurudzirawo kuti vanhu vane psoriasis vashandise mafuta-asina sipo uye isina dhayi, sipo, uye zvinodzikisira kuchengetedza kutsamwa kweganda kusvika padiki.

Pano, isu tichatsanangura zvakajairika kurapwa kwe psoriasis, kubva kwekutanga-mutsara marapirwo senge misoro yemakemikari kuenda kukirasi nyowani yemishonga inonzi biologics.

Misoro yekurapa ye psoriasis

Mishonga inoshandiswa zvakananga paganda inonzi mishonga yekurapa. Zvinosanganisira:

• mafuta
• mafuta okuzora
• mafuta
• gels

Ivo anowanzo ari mutsetse wekutanga wekurapa kwevanhu vane hunyoro kusvika pakuenzanisa psoriasis. Mune zvimwe zviitiko, anoshandiswa pamwe chete neimwe mhando yekurapa.

Corticosteroid-ine makirimu uye mafuta ndiwo marapirwo akajairika e psoriasis. Aya akadzika-dose steroid mishonga inoshanda kudzora kuwanda kugadzirwa kwemasero eganda uye kunyaradza ganda. Zvisinei, mamwe corticosteroids anosanganisira steroid yakasimba iyo inogona kuita kuti zviratidzo zvako zviwedzere. Chiremba wako achaziva simba chairo rekudzora zviratidzo zvako, pane kuti uwedzere.

Misoro retinoid ndeimwe mhando yekurapa kwakatorwa kubva muvhitamini A. Ivo vanoshanda kugadzirisa chiitiko chekukura mumaseru eganda. Izvi zvinoderedza kuzvimba. Kunyangwe isiri yekukurumidza kuita seye corticosteroid ointments, epamusoro retinoids ine mashoma mhedzisiro. Vakadzi vane nhumbu kana vanogona kutora nhumbu havafanirwe kushandisa izvi nekuda kwenjodzi yekuremara kwekuzvara.

Vitamin D zvakafanana

Aya ndiwo mafomu ekugadzira e vitamini D ayo anoderedza ganda kukura kwesero. Chiremba wako anogona kuvanyorera ivo vega kana nemamwe marapirwo ekurapa zvinyoro kusvika zvine mwero psoriasis. Zvinosanganisira:

• calcipotriene (Dovonex)
• calcitriol (Rocaltrol)

Marasha tara makirimu kana mafuta ekuzora

Marasha tara ndiyo yechinyakare kurapwa kweiyo psoriasis. Yakagadzirwa kubva kune zvigadzirwa zve petroleum kugadzira. Marasha tara zvigadzirwa zvinoderedza kuyerwa, kuchenesa, uye kuzvimba. Kukwirira kwakanyanya kunowanikwa nemushonga.

Aya makirimu ane zvimwe zvakaderera, zvisinei. Tara yemarasha yakashata, uye inogona kusvibisa mbatya nemubhedha. Inogona zvakare kuva nehunhu hwakasimba uye husingafadzi.

Mashambi shampoos

Mishonga uye yekunyorerwa-simba shwadhi shampoo dzinowanikwa kubva kuna chiremba wako kurapa psoriasis pachikanda chako.

Salicylic acid uye lactic acid

Ose maviri easidhi aya anokurudzira kutsvedza kwemasero eganda akafa, izvo zvinoderedza kuyerwa. Inogona zvakare kushandiswa mukubatana nemamwe marapirwo. Ivo anowanikwa muOTC uye mushonga mushonga.

Zvirongwa zvehurongwa zve psoriasis

Mishonga yekunyorera inogona kubatsira kurwisa kupararira kwe psoriasis nekugadzirisa kuzvimba.

Vanachiremba vanowanzo sarudza kushandisa yakaderera mwero yekurapa inodiwa kumisa zviratidzo. Ivo vanotanga nemusoro wenyaya kurapwa kazhinji. Sezvo ganda rinova rinoramba uye risingachapindure kune kumwe kurapwa, kurapa kwakasimba kunogona kushandiswa.

Chiremba wako anogona kupa mishonga yemumuromo kana yekubaiwa kana psoriasis yako yakanyanyisa kana kusapindura sarudzo dzemusoro. Mazhinji emishonga iyi ane mhedzisiro, saka vanachiremba vanoisa mashandisiro avo kumatambudziko akaoma kana anoramba aripo.

Methotrexate

Methotrexate inoderedza kugadzirwa kwemasero eganda uye inodzvinyirira immune immune. Vanachiremba vanowanzo gadza izvi kune vanhu vane zvine mwero kusvika zvakanyanya psoriasis. Iyo ndeimwe yemishonga inoshanda kwazvo kune vanhu vane erythrodermic psoriasis kana pustular psoriasis. Munguva pfupi yapfuura, vanachiremba vakatanga kuitora semushonga weporioriatic arthritis zvakare.

Zvimwe zvinokanganisa zvinosanganisira:

• kurasikirwa nenzara
• kuneta
• kugumbuka mudumbu

Cyclosporine

Cyclosporine mushonga unoshanda zvakanyanya wakagadzirirwa kudzvinyirira immune system. Vanachiremba vanowanzopa mushonga uyu kune vanhu chete vane chirwere chakakomba che psoriasis nekuti inokanganisa immune system.

Vazhinji vanachiremba zvakare vanongoraira uyu mushonga kwenguva pfupi yenguva nekuda kwenjodzi yekukwirisa kweropa. Kana iwe ukatora mushonga uyu, iwe unozoda kugara uchiongororwa ropa uye kuongororwa kweropa kuti utarise kuti zvingangoita matambudziko.

PDE4 inhibitors

Mushonga mumwe chete wemumuromo, unonzi apremilast (Otezla), uripo parizvino mukirasi nyowani yemishonga ye psoriasis. Hazvinyatsonzwisisike kuti apremilast inoshanda sei kurapa psoriasis. Inofungidzirwa kushanda nekuderedza mhinduro yemuviri wako kuzvimba.

Retinoids

Retinoids inogadzirwa kubva kune vhitamini A zvigadzirwa. Vanorapa zvine mwero kusvika zvakanyanya psoriasis nekudzora kugadzirwa kwemasero eganda. Chiremba wako anogona kukuudza kuti iwe ushandise izvi neyakareruka kurapa.

Sezvo nemimwe mishonga yesystem, izvi zvine zvimwe zvinogona kuve nemhedzisiro. Chiremba wako anogona kuraira kuongororwa ropa nguva dzose kuti atarise cholesterol yakawanda, iri dambudziko rinowanzoitika kune vanhu vari pamushonga uyu. Retinoids inogona zvakare kukonzera kuremara kwekuberekwa. Vakadzi vane nhumbu kana vanoshuvira kuve nepamuviri havafanirwe kutora mushonga uyu.

Iyo chete FDA-inogamuchirwa yemuromo retinoid yekurapa psoriasis ndeye acitretin (Soriatane).

Hydroxyurea

Hydroxyurea ndeyekirasi yemishonga inonzi antimetabolites. Inofungidzirwa kushanda nekudzivisa kudzokorora kweDNA. Inogona kushandiswa nefototherapy, asi haina kushanda senge cyclosporine uye methotrexate.

Mhedzisiro inogona kuitika inosanganisira masero matsvuku eropa ayo akaderera zvakanyanya (kupererwa neropa) uye kuderera kwemasero machena eropa nemaplatelet. Vakadzi vane nhumbu kana kuronga kuve nepamuviri havafanire kutora hydroxyurea nekuda kwenjodzi yekuremara kwekuzvara nekuparara.

Immunomodulator zvinodhaka (biologics)

Biologics iri nyowani kirasi yemishonga inovavarira mhinduro yemumuviri wako. Iyi mishonga inopihwa jekiseni kana infravenous infusion (IV). Vanachiremba vanowanzo vapa iwo kuvanhu vane zvine mwero uye zvakanyanya psoriasis vasina kupindura kuchinyakare kurapwa.

Iyo biologics inogamuchirwa yekurapa psoriasis ndeiyi:

• adalimumab (Humira)
• etanercept (Enbrel)
• certolizumab (Cimzia)
• infliximab (Remicade)
• ustekinumab (Stelara)
• secukinumab (Cosentyx)
• ixekizumab (Taltz)
• brodalumab (Siliq)
• guselkumab (Tremfya)
• tildrakizumab (Ilumya)
• risankizumab (Skyrizi)

Biosimilars zvakare achangobva kuwanikwa, ayo akafanana neakapihwa zita-zita biologic zvinodhaka, asi kwete chaiyo kopi. Ivo vanotarisirwa kuve nemhedzisiro yakafanana neyakajairika mushonga. Ikozvino pane biosimilars ye infliximab uye etanercept.

Thioguanine

Thioguanine inoshandiswa off-label kurapa psoriasis. Kunyangwe isiri kushanda se methotrexate kana cyclosporine, thioguanine ine mashoma mhedzisiro. Izvi zvinoita kuti ive inoratidzika yekurapa sarudzo. Nekudaro, zvichiri kungakonzera kuremara kwekuberekwa. Vakadzi vane nhumbu kana kuronga kuve nepamuviri havafanirwe kuitora.

Kunyoresa mazita ekushandisa zvinodhaka

• Kushandisa-kurebesa kushandisa zvinodhaka zvinoreva kuti mushonga unobvumidzwa neDFA nechinangwa chimwe unoshandiswa nechinangwa chakasiyana chisina kubvumidzwa. Nekudaro, chiremba achiri kugona kushandisa mushonga wechinangwa icho. Izvi zvinodaro nekuti iyo FDA inodzora kuyedzwa uye kubvumidzwa kwemishonga, asi kwete mashandisiro anoita vanachiremba mishonga yekurapa varwere vavo. Nekudaro, chiremba wako anokwanisa kukunyorera mushonga asi ivo vanofunga zvakanakira iwe.

Phototherapy (light therapy)

Phototherapy maitiro ayo ganda rinonyatso kuburitswa kune yakasikwa kana yekugadzirwa ultraviolet (UV) mwenje.

Izvo zvakakosha kuti ukurukure phototherapy neye dermatologist yako usati wazviburitsa iwe kune yakakwira mwero we UV UV. Yakareba-refu phototherapy inosanganisirwa nekuwedzera zviitiko zvegomarara reganda, kunyanya melanoma. Usambofa wakaedza kuzvirapa nemubhedha wekupukuta kana sunbathing.

Chiedza chezuva

Icho chinonyanya kusikwa kwe UV UV izuva. Iyo inogadzira UVA mwaranzi. UV mwenje inoderedza T cell kugadzirwa uye pakupedzisira inouraya chero akaomeswa T masero. Izvi zvinoderedza kudzikisira kupindura uye ganda sero shanduko.

Kufumurwa kupfupi kune mashoma ezuva anogona kuvandudza psoriasis. Zvisinei, kupisa kwakanyanya kwezuva kana kusvibiswa kwezuva kwenguva refu kunogona kukuvadza zviratidzo. Inogona zvakare kukonzera kukuvara kweganda uye inogona kuwedzera mikana yako yekuva nekenza yeganda.

UVB phototherapy

Kune zvinyoro nyoro zve psoriasis, yekunyepedzera mwenje yekurapa ine UVB mwenje inogona kushandiswa.Nekuti UVB-inoburitsa mwenje mabhokisi anoshandiswa kazhinji kurudzi urwu rwekurapwa, zvigamba chimwe chete kana zvidiki zveganda zvinogona kurapwa, panzvimbo pekufumura muviri wese.

Zvimwe zvinokanganisa zvinosanganisira kujeka, kuoma ganda uye kutsvuka munzvimbo dzakarapwa.

Goeckerman kurapwa

Kubatanidza kurapwa kweUVB nemarara emarasha kunoita kuti marapirwo maviri abudirire kupfuura chero kurapwa kwega. Tara yemarasha inoita kuti ganda riwedzere kugamuchira UVB mwenje. Iyi kurapa inoshandiswa kune akapfava kusvika pakuenzanisa kesi.

Excimer Laser

Laser kurapa kusimudzira kunovimbisa mukurapa kweiyo nyoro kusvika pakuenzanisa psoriasis. Lasers inogona kunongedza matanda akaomeswa eUVB mwenje pane psoriatic patches pasina kukanganisa ganda rakakomberedza. Asi zvinogona kungobatsira pakurapa zvidimbu zvidiki sezvo laser isingakwanise kufukidza nzvimbo hombe.

Photochemotherapy, kana psoralen pamwe ultraviolet A (PUVA)

Psoralen inorapa-inosimudzira mishonga inogona kusanganiswa neUVA mwenje kurapa senzira yekurapa psoriasis. Varwere vanotora mushonga kana kuisa kirimu vhezheni paganda vopinda muUVA light box. Uku kurapa kunowedzera hasha uye kunowanzo shandiswa kune varwere vane mwero kusvika kumatambudziko akaoma e psoriasis.

Pulsed dhayi laser

Chiremba wako anogona kukurudzira pulsed dhayi laser kana mamwe marapirwo asina kukwana kubudirira. Maitiro aya anoparadza midziyo midiki yeropa munzvimbo dzakapoteredza psoriasis mabara, kucheka kuyerera kweropa uye kudzikisa kukura kwesero munzvimbo iyoyo.