Vincristine: chii icho, chii chairi uye mhedzisiro

Zvemukati

• Chii ichochi
• Kushandisa sei
• Contraindications
• Zvinogona kuitika mhedzisiro

Vincristine ndicho chinhu chinoshanda mune antineoplastic mushonga unozivikanwa nekutengesa seOncovin, inoratidzirwa kurapwa kwemhando dzakasiyana dzekenza, kusanganisira leukemia, mapapu uye gomarara repazamu.

Chiito chayo kupindira metabolism yemamino acids uye kudzivirira maseru kupatsanurwa, kudzikisira mukana wekenza inopararira nemuviri.

Mushonga uyu unowanikwa sejekiseni uye unofanirwa kupihwa nachiremba wehutano.

Chii ichochi

Vincristine imushonga unoratidzwa pakurapwa kweanotevera marudzi ekenza:

• Acute lymphoid leukemia;
• Neuroblastoma;
• Bundu raWilms;
• Gomarara repazamu;
• Kenza yemapapu;
• Gomarara repamuviri;
• Gomarara remuromo wechibereko;
• Kenza yakajeka;
• Hodgkin's uye isiri-Hodgkin's lymphoma;
• Ewing's sarcoma;
• Osteosarcoma;
• Malignant melanoma.

Uye zvakare, uyu mushonga unoratidzwa zvakare pakurapa mycosis fungoides uye idiopathic thrombocytopenic purpura. Dzidza zvazviri uye kuti ungaziva sei zviratidzo zveiopathic thrombocytopenic purpura.

Kushandisa sei

Mushonga uyu unofanirwa kupihwa mukati mehusimbe, nehutano nyanzvi, uye muyero uye nguva yekurapwa inofanirwa kutemerwa neanoratidzi.

Kazhinji, muyero unotevera:

Vakuru

• 0.01 kusvika ku0.03 mg yeVincristine pa kg yehuremu hwemuviri, seyero imwe chete, mazuva ese manomwe.

Vana

• Pamusoro pe10 kg: Tungamira 1.5 kusvika 2 mg yeVincristine pamamita mita imwe yemuviri wemuviri, seyero imwe chete, mazuva ese manomwe;
• Iine 10 kg kana pasi: Tungamira 0.05 mg yeVincristine pa kg yehuremu hwemuviri, seyero imwe chete, mazuva ese manomwe.

Iyo nguva yekurapa inofanirwa kutemerwa ne oncologist.

Contraindications

Mushonga uyu unopikiswa kune vanhu vane hypersensitivity kune izvo zvikamu zveiyo fomula uye kune varwere vane fomu yekudzikisira yeCharcot-Marie-Tooth syndrome.

Uye zvakare, haifanire kushandiswa nevakadzi vane pamuviri uye vakadzi vari kuyamwisa vanofanirwa kumisa lactation panguva yekurapwa neincincine.

Zvinogona kuitika mhedzisiro

Mimwe yemhedzisiro inowanzoitika panguva yekurapwa neincincine kurasikirwa bvudzi, kuzvimbirwa, kurwadziwa mumuviri, kuderera kwemasero machena eropa, kurasikirwa kwekunzwa, kunetseka kufamba uye kurasikirwa kwekufungisisa.

Iyo yakakomba mhedzisiro mhedzisiro iyo inogona kuitika ndeye neuromuscular kusagadzikana.