Kenza yechiropa - hepatocellular carcinoma

Hepatocellular carcinoma igomarara rinotanga muchiropa.

Hepatocellular carcinoma inokonzera kenza dzakawanda dzechiropa. Rudzi urwu rwegomarara runowanzoitika kuvarume kupfuura vakadzi. Inowanzoonekwa muvanhu vane makore makumi mashanu kana kudarika.

Hepatocellular carcinoma haina kufanana nekenza yechiropa, iyo inotanga mune imwe nhengo (senge zamu kana colon) uye inopararira kuchiropa.

Muzviitiko zvakawanda, chinokonzera kenza yechiropa kukuvara kwenguva refu uye kupora kwechiropa (cirrhosis). Cirrhosis inogona kukonzerwa ne:

• Kunwa doro zvisina kufanira
• Zvirwere zvemuviri zvechiropa
• Hepatitis B kana hutachiona hwehepatitis C hutachiona
• Kuzvimba kwechiropa icho chiri chenguva refu (chisingaperi)
• Iron inoremedza mumuviri (hemochromatosis)

Vanhu vane hepatitis B kana C vane njodzi huru yekenza yechiropa, kunyangwe kana vasina kukura cirrhosis.

Zviratidzo zvegomarara rechiropa zvinogona kusanganisira chero eanotevera:

• Kusuruvara kwepamuviri kana hunyoro, kunyanya muchikamu chepamusoro-kurudyi
• Kupwanya kuri nyore kana kubuda ropa
• Akawedzera mudumbu (ascites)
• Ganda jena kana maziso (jaundice)
• Kusanzwisisika kuonda

Anopa hutano anoita bvunzo dzepanyama uye obvunza nezve zviratidzo zvako. Iko kuongorora kwepanyama kunogona kuratidza kuwedzera, kwakapfava chiropa kana zvimwe zviratidzo zvecirrhosis.

Kana mupi achifungidzira gomarara rechiropa, bvunzo dzinogona kurairwa dzinosanganisira:

• Abdominal CT scan
• Abdominal MRI scan
• Abdominal ultrasound
• Chiropa biopsy
• Chiropa basa bvunzo
• Serum alpha fetoprotein

Vamwe vanhu vane mukana wakakura wekuita gomarara rechiropa vanogona kuwana kuongororwa ropa nguva nenguva uye maastround ekuona kana mamota ari kukura.

Kuti unyatsoongorora hepatocellular carcinoma, bhaopsy yebundu rinofanira kuitwa.

Kurapa kunoenderana nekuti kenza yakwira sei.

Kuvhiya kunogona kuitwa kana bundu risina kupararira. Asati avhiyiwa, bundu rinogona kurapwa nechemotherapy kudzikisa saizi. Izvi zvinoitwa nekuendesa mushonga wakananga muchiropa nehubhu (catheter) kana nekuupa mukati mehusimbe (neIV).

Radiation kurapwa munzvimbo yekenza inogona zvakare kubatsira.

Ablation ndiyo imwe nzira ingangoshandiswa. Ablate zvinoreva kuparadza. Mhando dzekubvisa dzinosanganisira kushandisa:

• Mafungu eredhiyo kana microwaves
• Ethanol (doro) kana acetic acid (vhiniga)
• Kutonhora kwakanyanya (cryoablation)

Kuiswa kwechiropa kunogona kukurudzirwa.

Kana gomarara risingakwanise kuvhiyiwa kana kupararira kunze kwechiropa, kazhinji hapana mukana wekupora kwenguva refu. Kurapa pachinzvimbo chinotarisa mukuvandudza uye kuwedzera hupenyu hwemunhu. Kurapa mune ino kesi kunogona kushandisa yakanangwa kurapwa nemishonga inogona kutorwa semapiritsi. Nyowani immunotherapy mishonga inogona zvakare kushandiswa.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Kana gomarara risingakwanise kurapwa zvachose, chirwere chinowanzo kuuraya. Asi kupona kunogona kusiyana, zvichienderana nekuti kenza iri kufambira mberi zvakadii kana yaonekwa uye kuti kurapwa kwakabudirira sei.

Fonera waunopa kana iwe uchiramba uchirwadziwa mudumbu, kunyanya kana uine nhoroondo yechiropa chirwere.

Matanho ekudzivirira anosanganisira:

• Kudzivirira uye kurapa hutachiona hepatitis kunogona kubatsira kudzikisa njodzi yako. Kuvharirwa kwevechidiki kurwisa hepatitis B kunogona kudzora njodzi yekenza yechiropa mune ramangwana.
• Usanwa doro rakawandisa.
• Vanhu vane mamwe marudzi ehemochromatosis (iron overload) vangangoda kuongororwa gomarara rechiropa.
• Vanhu vane hepatitis B kana C kana cirrhosis vanogona kukurudzirwa kuongororwa kenza yechiropa.

Chiropa chepakutanga cell carcinoma; Tumor - chiropa; Cancer - chiropa; Hepatoma

• Kugaya chirongwa
• Chiropa biopsy
• Kenza yeHepatocellular - CT scan

Abou-Alfa GK, Jarnagin W, Dika IE, et al. Chiropa uye bile duct cancer. Mune: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020: chits. 77.

Di Bisceglie AM, Befeler AS. Hepatic tumors uye cysts. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chirwere: Pathophysiology / Diagnosis / Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 96.

National Cancer Institute webhusaiti. Vakuru vepakutanga kurapwa kenza yechiropa (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq. Yakagadziridzwa Kurume 24, 2019. Yakasvika Nyamavhuvhu 27, 2019.

National Yakakwana Cancer Network webhusaiti. NCCN kiriniki yekudzidzira maitiro mune oncology: hepatobiliary cancer. Shanduro 3.2019. www.nccn.org/professionals/physician_gls/pdf/hepatobiliary.pdf. Yakagadziridzwa Nyamavhuvhu 1, 2019. Yakasvika Nyamavhuvhu 27, 2019.