Hemochromatosis

Hemochromatosis mamiriro umo mune iron yakawandisa mumuviri. Iyo inonzi zvakare kuwandisa kwesimbi.

Hemochromatosis inogona kunge iri geni kusagadzikana inopfuudzwa kuburikidza nemhuri.

• Vanhu vane mhando iyi vanotora simbi yakawandisa kuburikidza nemudumbu wavo. Simbi inovaka mumuviri. Chiropa, moyo, uye rwatata inhengo dzakajairika uko simbi inovaka.
• Iyo iripo pakuzvarwa, asi inogona kunge isingawanikwe kwemakore.

Hemochromatosis inogona zvakare kuitika semhedzisiro ye:

• Zvimwe kusagadzikana kweropa, senge thalassemia kana mamwe anemias. Kuwedzerwa kuwedzerwa kweropa nekufamba kwenguva kunogona kutungamira pakuwanda kwesimbi.
• Yenguva refu-yekushandisa doro uye mamwe mamiriro ehutano.

Dambudziko iri rinobata varume vazhinji kupfuura vakadzi. Zvakajairika muvanhu vachena vanobva kuchamhembe kweEurope.

Zviratidzo zvinogona kusanganisira chero zvinotevera:

• Marwadzo emudumbu
• Kuneta, kushaya simba, kushaya simba
• Yakajairika kusviba kweganda reganda (inowanzozonzi bronzing)
• Joint kurwadziwa
• Kurasikirwa nevhudzi remuviri
• Kurasikirwa kwechido chepabonde
• Kuonda

Anopa hutano anoita bvunzo dzepanyama. Izvi zvinogona kuratidza chiropa uye spleen kuzvimba, uye ganda rinochinja.

Kuongororwa kweropa kunogona kubatsira kuti kuongororwa. Miedzo inogona kusanganisira:

• Chikamu cheFerritin
• Chikamu chesimbi
• Percentage yeTranserrin saturation (yakakwira)
• Kuongorora genetic

Mimwe bvunzo inogona kusanganisira:

• Ropa shuga (glucose) mwero
• Alpha fetoprotein
• Echocardiogram kuongorora mashandiro emoyo
• Electrocardiogram (ECG) kutarisa mashandiro emagetsi emoyo
• Kufungidzira bvunzo senge CT scans, MRI, uye ultrasound
• Chiropa basa bvunzo

Mamiriro acho anogona kusimbiswa nechiropa biopsy kana kuongororwa kwemajini. Kana hutachiona hukasimbiswa, kumwe kuongororwa kweropa kunogona kushandiswa kuona kana dzimwe nhengo dzemhuri dziri panjodzi yekuwandisa iron.

Chinangwa chekurapa kubvisa simbi yakawandisa kubva mumuviri uye kurapa chero kukuvara kwemitezo.

Maitiro anonzi phlebotomy ndiyo yakanakisa nzira yekubvisa yakawandisa iron kubva mumuviri:

• Imwe hafu litre yeropa inobviswa mumuviri vhiki imwe neimwe kusvikira zvitoro zvemuviri zvapera. Izvi zvinogona kutora mwedzi yakawanda kuti uite.
• Mushure meizvozvo, maitiro acho anogona kuitwa zvishoma kazhinji kuchengetedza yakajairwa simbi yekuchengetedza.

Nei maitiro acho achidikanwa zvinoenderana nezviratidzo zvako uye nematanho ehemoglobin uye serum ferritin uye kuti yakawanda sei simbi yaunotora mukudya kwako.

Mamwe matambudziko ehutano senge chirwere cheshuga, kudzikira kwe testosterone mumarume, arthritis, kukundikana kwechiropa, uye kushaya moyo kucharapwa.

Kana iwe ukaonekwa uine hemochromatosis, wako mupi anogona kukurudzira kudya kuti udzikise kuti yakawanda sei iron inopinzwa kuburikidza neyako yekugaya nzira. Mupi wako anogona kukurudzira zvinotevera:

• Usanwa doro, kunyanya kana uine kukuvara kwechiropa.
• Usatore mapiritsi esimbi kana mavitamini ane ayoni.
• Usashandise iron cookware.
• Deredza chikafu chakasimbiswa nesimbi, senge zana muzana ezviyo zvemangwanani zvine iron.

Kusarapwa, kuwandisa kwesimbi kunogona kutungamira kukuvara kwechiropa.

Yakawedzera simbi inogona zvakare kuvaka mune dzimwe nzvimbo dzemuviri, kusanganisira iyo thyroid gland, machende, pancreas, pituitary gland, moyo, kana majoini. Kurapa kwekutanga kunogona kubatsira kudzivirira kunetseka senge chirwere chechiropa, chirwere chemwoyo, arthritis kana chirwere cheshuga.

Unyatsoita sei zvinoenderana nehuwandu hwekukuvara kwemitezo. Kumwe kukuvara kwemitezo kunogona kudzoserwa apo hemochromatosis inoonekwa nekukurumidza uye ikarapwa zvine hukasha ne phlebotomy.

Matambudziko anosanganisira:

• Chiropa cirrhosis
• Chiropa kutadza
• Kenza yechiropa

Chirwere ichi chinogona kutungamira mukusimudzira kwe:

• Arthritis
• Chirwere cheshuga
• Zvinetso zvemwoyo
• Kuwedzera kwenjodzi yehumwe hutachiona hutachiona
• Testicular atrophy
• Ruvara rweganda rinochinja

Fonera waunopa kana zviratidzo zve hemochromatosis zvichikura.

Fonera musangano kuti uwane musangano nemupi wako (kuti uongorore) kana nhengo yemhuri yaonekwa kuti ine hemochromatosis.

Kuongorora nhengo dzemhuri dzemunhu anoonekwa aine hemochromatosis anogona kuona chirwere ichi nguva isati yakwana kuitira kuti kurapwa kutange kusati kwakuvadzwa kwemitezo kwaitika mune dzimwe hama dzakabatwa.

Iron kuwandisa; Ropa kuwedzerwa - hemochromatosis

• Hepatomegaly

Bacon BR, Fleming RE. Hemochromatosis. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chirwere: Pathophysiology / Diagnosis / Management. 11th ed. Philadelphia, PA: Elsevier; 2021: chits. 75.

Brittenham GM. Kukanganiswa kwesimbi homeostasis: kushomeka kwesimbi uye kuwandisa. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits. 36.