Eosinophilic fasciitis

Eosinophilic fasciitis (EF) chirwere umo zvinyama pasi peganda uye pamusoro pemhasuru, inonzi fascia, inozvimba, inotsva uye gobvu. Ganda riri pamaoko, makumbo, mutsipa, dumbu kana tsoka zvinogona kuzvimba nekukurumidza. Mamiriro acho haana kujairika.

EF inogona kutaridzika yakafanana nescleroderma, asi haina hukama. Kusiyana ne scleroderma, muEF, zvigunwe hazvibatanidzwe.

Chikonzero cheEF hachizivikanwe. Kazhinji kesi zvakaitika mushure mekutora L-tryptophan zvinowedzera. Mune vanhu vane chirwere ichi, masero machena eropa, anonzi eosinophil, anovaka mumhasuru nematomu. Eosinophils inosanganiswa neergic reaction. Iyo syndrome inowanzoitika muvanhu vane makore makumi matatu kusvika makumi matanhatu.

Zviratidzo zvinogona kusanganisira:

• Unyoro uye kuzvimba kweganda pamaoko, makumbo, kana dzimwe nguva majoini (kazhinji pamativi ese emuviri)
• Arthritis
• Carpal tunnel chirwere
• Kutambudzika kwemhasuru
• Ganda rakafuta rinotaridzika kunge rakapetwa

Miedzo inogona kuitwa inosanganisira:

• CBC ine mutsauko
• Gamma globulins (rudzi rwe immune system protein)
• Erythrocyte sedimentation chiyero (ESR)
• MRI
• Tsvina biopsy
• Ganda biopsy (iyo biopsy inoda kusanganisira iyo yakadzika tishu yeiyo fascia)

Corticosteroids uye mimwe mishonga inodzvinyirira immune inoshandiswa kugadzirisa zviratidzo. Iyi mishonga inoshanda zvakanyanya kana ikatanga pakutanga kwechirwere. Nonsteroidal anti-inflammatory drug (NSAIDs) inogona kubatsirawo kudzikisa zviratidzo.

Muzviitiko zvakawanda, mamiriro acho anoenda mukati memakore matatu kusvika matatu. Zvisinei, zviratidzo zvinogona kugara kwenguva refu kana kudzoka.

Arthritis chinhu chisingawanzoitika cheEF. Vamwe vanhu vanogona kukura zvakanyanya kukanganiswa kweropa kana kenza ine hukama neropa, senge aplastic anemia kana leukemia. Iko kutarisisa kwakanyanya zvakanyanya kana chirwere cheropa chikaitika.

Fonera wako mupi wezvehutano kana iwe uine zviratidzo zveichi chirwere.

Iko hakuna kunozivikanwa kudzivirira.

Shulman chirwere

• Mashura epamberi epamusoro

Aronson JK. Tryptophan. Mune: Aronson JK, ed. Meyler's Side Migumisiro yeMishonga. 16 ed. Waltham, MA: Elsevier BV ;; 2016: 220-221.

James WD, Elston DM, Bata JR, Rosenbach MA, Neuhaus IM. Zvinobatanidza zvinyama zvirwere. Muna: James WD, Elston DM, Bata JR, Rosenbach MA, Neuhaus IM, eds. Andrews 'Zvirwere zveGanda: Clinical Dermatology. 13 ed. Philadelphia, PA: Elsevier; 2020: chits. 8.

Lee LA, Werth VP. Ganda uye rheumatic zvirwere. Mune: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley uye Firestein's Bhuku reRheumatology. 10th ed. Philadelphia, PA: Elsevier; 2017: chitsiko 43.

Pinal-Fernandez I, Selva-O 'Callaghan A, Grau JM. Kuongororwa uye kupatsanurwa kweeosinophilic fasciitis. Autoimmun Zvak. 2014; 13 (4-5): 379-382. PMID: 24424187 www.ncbi.nlm.nih.gov/pubmed/24424187.

National Sangano reRare Dambudziko. Eosinophilic fasciitis. rarediseases.org/rare-diseases/eosinophilic-fasciitis/. Yakagadziridzwa 2016. Yakasvika munaKurume 6, 2017.