Giant cell arteritis

Giant cell arteritis kuzvimba uye kukuvara kune tsinga dzinopa ropa kumusoro, mutsipa, kumusoro muviri nemaoko. Inonziwo temporal arteritis.

Giant cell arteritis inokanganisa aripakati-kusvika-makuru arteri. Izvo zvinokonzeresa kuzvimba, kuzvimba, unyoro, uye kukuvara kune tsinga dzeropa dzinopa ropa kumusoro, mutsipa, kumusoro muviri, nemaoko. Inowanzoitika mumariti akakomberedza tembere (arteriyal arteri). Iyi tsinga inobuda kubva kune carotid arteri mumutsipa. Mune zvimwe zviitiko, mamiriro acho anogona kuitika mune epakati-kusvika-makuru arteri mune dzimwe nzvimbo mumuviri zvakare.

Chikonzero chemamiriro acho hachizivikanwe. Iyo inofungidzirwa kuti inokodzera muchidimbu kune yakashata immune mhinduro. Dambudziko iri rakabatanidzwa kune zvimwe hutachiona uye kune mamwe majini.

Giant cell arteritis inowanzoitika kune vanhu vane chimwe chirwere chekuputira chinonzi polymyalgia rheumatica. Giant cell arteritis inowanzoitika muvanhu vanopfuura makore makumi mashanu. Inowanzoitika kune vanhu vanobva kuchamhembe kweEurope. Mamiriro acho anogona kumhanya mumhuri.

Zvimwe zvinowanzoonekwa zviratidzo zveichi dambudziko ndezvi:

• Mutsva unopwanya musoro kune rumwe rutivi rwemusoro kana kumashure kwemusoro
• Unyoro kana uchibata ganda romusoro

Zvimwe zviratidzo zvinogona kusanganisira:

• Kurwadziwa kwemajaya kunoitika kana uchitsenga
• Marwadzo paruoko mushure mekuishandisa
• Tsvina inorwadza
• Marwadzo uye kuomarara mumutsipa, maoko ekumusoro, bendekete uye chiuno (polymyalgia rheumatica)
• Kushaya simba, kuneta zvakanyanya
• Kupindwa nechando
• Kazhinji kurwara kunzwa

Zvinetso nekuona zvinogona kuitika, uye dzimwe nguva zvinogona kutanga kamwe kamwe. Aya matambudziko anosanganisira:

• Kuona kwakashata
• Kuona kaviri
• Kamwe kamwe kuderedzwa kuona (kupofumadza mune rimwe kana ese maziso)

Anopa hutano anoongorora musoro wako.

• Ganda remusoro rinowanzo nyoro kubata.
• Panogona kuve paine hunyoro, hwakakora tsinga kune rumwe rutivi rwemusoro, kazhinji kazhinji pamusoro peimwe kana ese mairi matembere.

Kuongororwa kweropa kunogona kusanganisira:

• Hemoglobin kana hematocrit
• Chiropa basa bvunzo
• Sedimentation rate (ESR) uye C-inoshanda mapuroteni

Kuongororwa kweropa chete hakugone kupa kuongororwa. Iwe unozofanirwa kuve neiyo biopsy yeyepanguva arteri. Iyi ndiyo nzira yekuvhiya inogona kuitwa seanorwara kunze.

Iwe unogona zvakare kuve nemimwe bvunzo, inosanganisira:

• Ruvara Doppler ultrasound yeiyo yemberi arteri. Izvi zvinogona kutora nzvimbo yeyeperi arteri biopsy kana ikaitwa nemunhu ane ruzivo nemaitiro acho.
• MRI.
• PET scan.

Kuwana kurapwa nekukurumidza kunogona kudzivirira matambudziko akakomba sekupofomara.

Kana giant cell arteritis ichifungidzirwa, iwe uchagamuchira corticosteroids, senge prednisone, nemuromo. Iyi mishonga inowanzotangwa kunyangwe biopsy isati yaitwa. Iwe unogona zvakare kuudzwa kutora aspirin.

Vanhu vazhinji vanotanga kunzwa zvirinani mukati memazuva mashoma mushure mekutanga kurapwa. Muyero wecorticosteroids unocheka kumashure zvishoma nezvishoma. Nekudaro, iwe unozofanirwa kutora mushonga we1 kusvika 2 makore.

Kana kuongororwa kwehofori cell arteritis kukaitwa, mune vanhu vazhinji mushonga webiologic unonzi tocilizumab ichawedzerwa. Mushonga uyu unoderedza huwandu hwecorticosteroids inodiwa kudzora chirwere.

Kurapa kwenguva refu nekorticosteroids kunogona kuita kuti mapfupa ave akaonda uye kuwedzera mukana wako wekutyoka. Iwe unozofanirwa kutora matanho anotevera kuchengetedza rako bhonzo.

• Dzivisa kusvuta uye kunyanya kunwa doro.
• Tora yakawedzera calcium uye vhitamini D (zvichibva pazano remupi wako).
• Kutanga kufamba kana mamwe mafomu ehuremu-hurema.
• Ita kuti mapfupa ako aongororwe nefupa remamineral density (BMD) bvunzo kana DEXA scan.
• Tora bisphosphonate mushonga, senge alendronate (Fosamax), sekurairwa nemupi wako.

Vanhu vazhinji vanoita kupora kwakazara, asi kurapwa kunogona kudikanwa kweanosvika makore maviri kana maviri kana kupfuura.Mamiriro acho anogona kudzoka pane imwe nguva inotevera.

Kukuvadza kune mimwe mitsipa yeropa mumuviri, senge aneurysms (kubharitsa kwemitsipa yeropa), kunogona kuitika. Uku kukuvara kunogona kutungamira sitiroko mune ramangwana.

Fonera mupiki wako kana iwe uine:

• Kutema musoro kusingaendi
• Kurasikirwa kwemaonero
• Zvimwe zviratidzo zve temporal arteritis

Iwe unogona kuendeswa kune nyanzvi inobata temporal arteritis.

Iko hakuna kunozivikanwa kudzivirira.

Arteritis - kwenguva; Cranial arteritis; Giant cell arteritis

• Carotid tsinga anatomy

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James WD, Elston DM, Bata JR, Rosenbach MA, Neuhaus IM. Zviratidzo zvevascular. Muna: James WD, Elston DM, Bata JR, Rosenbach MA, Neuhaus IM, eds. Andrews 'Zvirwere zveGanda: Clinical Dermatology. 13 ed. Philadelphia, PA: Elsevier; 2020: chits. 35.

Koster MJ, Matteson EL, Warrington KJ. Yakakura-mudziyo hofori sero arteritis: kuongororwa, kuongorora uye manejimendi. Rheumatology (Oxford). 2018; 57 (suppl_2): ii32-ii42. PMID: 29982778 www.ncbi.nlm.nih.gov/pubmed/29982778.

Dombo JH, Tuckwell K, Dimonaco S, et al. Kuedzwa kwe tocilizumab mu giant-cell arteritis. N Engl J Med. 2017; 377 (4): 317-328. PMID: 28745999 www.ncbi.nlm.nih.gov/pubmed/28745999.

Tamaki H, Hajj-Ali RA. Tocilizumab yegoridhe cell arteritis-nyowani hofori nhanho muchirwere chekare. JAMA Neurol. 2018; 75 (2): 145-146. PMID: 29255889 www.ncbi.nlm.nih.gov/pubmed/29255889.