Munyori: Marcus Baldwin
Zuva Rekusika: 16 Chikumi 2021
Gadziridza Zuva: 18 Mbudzi 2024
Anonim
Wechidiki idiopathic arthritis - Mushonga
Wechidiki idiopathic arthritis - Mushonga

Juvenile idiopathic arthritis (JIA) izwi rinoshandiswa kutsanangura boka rematambudziko muvana anosanganisira arthritis. Idzo ndidzo dzenguva refu (dzisingaperi) hosha dzinokonzeresa marwadzo pamwe uye kuzvimba. Mazita anotsanangura iri boka remamiriro akachinja pamusoro pemakumi emakore apfuura sezvo zvimwe zvichidzidzwa nezve mamiriro acho.

Chikonzero cheJIA hachizivikanwe. Iyo inofungidzirwa kuve autoimmune chirwere. Izvi zvinoreva kuti muviri unorwisa uye unoparadza nyama yemuviri noutano nekukanganisa.

JIA inowanzo kukura isati yasvika makore 16. Zviratidzo zvinogona kutanga sekutanga kwemwedzi mitanhatu.

Sangano reInternational League of Associations reRheumatology (ILAR) rakaronga nzira inotevera yekumisikidza rudzi urwu rwehutano hweArthritis.

  • Systemic-kutanga JIA. Inosanganisira kuzvimba kwekubatana kana kurwadziwa, kupisa, uye kuputika. Ndiyo mhando isinganyanyozivikanwa asi inogona kuve yakanyanya kuomarara. Inoita kunge yakasiyana nedzimwe mhando dzeJIA uye yakafanana neAdult Onset Stills Chirwere.
  • Polyarthritis. Inosanganisira majoini mazhinji. Iyi fomu yeJIA inogona kuchinja kuita rheumatoid arthritis. Inogona kusanganisira mashanu kana anopfuura makuru uye madiki majoini emakumbo nemaoko, pamwe neshaya nemutsipa. Rheumatoid factor inogona kunge iripo.
  • Oligoarthritis (inoenderera uye inowedzera). Inosanganisira majoini 1 kusvika ku4, kazhinji kazhinji mawoko, kana mabvi. Inokanganisawo maziso.
  • Enthesitis-yakabatana arthritis. Inomiririra spondyloarthritis muvanhu vakuru uye kazhinji inosanganisira mubatanidzwa we sacroiliac.
  • Psoriatic arthritis. Inoonekwa muvana vane arthritis uye psoriasis kana chirwere chechipikiri, kana vane nhengo yepedyo yemhuri ine psoriasis.

Zviratidzo zveJIA zvinogona kusanganisira:


  • Dzimba dzakatsvuka, dzvuku, kana inodziya
  • Kukamhina kana matambudziko kushandisa gumbo
  • Pakarepo kupisa kwakanyanya, uko kunogona kudzoka
  • Rash (pane trunk uye kumagumo) iyo inouya uye inoenda nefivha
  • Kuomarara, kurwadziwa, uye kufamba kushoma kwekubatana
  • Kutambudzika kwakadzoka shure kusingaendi
  • Zviratidzo zvemuviri wese zvakaita seganda rakachenuruka, kuzvimba lymph gland, uye kuratidzika kwekurwara

JIA inogona zvakare kukonzera matambudziko emaziso anonzi uveitis, iridocyclitis, kana iritis. Panogona kunge pasina zviratidzo. Kana zviratidzo zvemaziso zvikaitika, zvinogona kusanganisira:

  • Maziso matsvuku
  • Kutambudzika kweziso, uko kunogona kuwedzera kana uchitarisa mwenje (photophobia)
  • Chiono chinoshanduka

Iko kuongorora kwepanyama kunogona kuratidza kuzvimba, kudziya, uye nyoro majoini anokuvadza kufamba. Mwana anogona kunge aine mapundu. Zvimwe zviratidzo zvinosanganisira:

  • Chiropa chakazvimba
  • Dzimba yekuzvimba
  • Kuzvimba lymph node

Kuongororwa kweropa kunogona kusanganisira:

  • Rheumatoid chinhu
  • Erythrocyte sedimentation chiyero (ESR)
  • Antinuclear nyowani (ANA)
  • Yakazara kuverenga ropa (CBC)
  • HLA-B27

Chero kana zvese izvi zvekuongororwa kweropa zvinogona kuve zvakajairika muvana vane JIA.


Anopa hutano anogona kuisa tsono mudiki kuzvimba kuti ibvise mvura. Izvi zvinogona kubatsira kutsvaga chikonzero cheArthritis. Inogona zvakare kubatsira kubvisa marwadzo. Iye mupi anogona kubaya steroids mubatanidzwa kubatsira kubatsira kudzimba.

Mimwe bvunzo inogona kuitwa inosanganisira:

  • X-ray yekubatana
  • Bone scan
  • X-ray yechipfuva
  • ECG
  • Kugara uchiongorora maziso ne ophthalmologist - Izvi zvinofanirwa kuitwa kunyangwe pasina zviratidzo zvemaziso.

Nonsteroidal anti-inflammatory drug (NSAIDs) senge ibuprofen kana naproxen inogona kukwana kudzora zviratidzo apo panongova nenhengo shomana dzejoini dzinobatanidzwa.

Corticosteroids inogona kushandiswa kune zvakanyanya kusimba kupisa-ups kubatsira kudzora zviratidzo. Nekuda kwehuturu hwavo, kushandiswa kwenguva refu kwemishonga iyi kunofanirwa kudzivirirwa muvana.

Vana vane arthritis muzvibatanidzwa zvakawanda, kana vane fever, mapundu, uye kuzvimba gland vangangoda mimwe mishonga. Izvi zvinonzi chirwere-chinogadzirisa antirheumatic zvinodhaka (DMARDs). Vanogona kubatsira kudzikisa kuzvimba mumajoini kana muviri. DMARD dzinosanganisira:


  • Methotrexate
  • Biologic zvinodhaka, senge etanercept (Enbrel), infliximab (Remicade), uye nezvimwe zvinodhaka.

Vana vane systemic JIA vangangoda biologic inhibitors yeIL-1 kana IL-6 senge anakinra kana tocilizumab.

Vana vane JIA vanofanirwa kugara vachishingaira.

Kuita maekisesaizi kunobatsira kuchengetedza mhasuru uye majoini avo akasimba uye nhare.

  • Kufamba, kuchovha bhasikoro, uye kushambira zvinogona kunge zviri zviitiko zvakanaka.
  • Vana vanofanirwa kudzidza kudziya vasati vaekisesaiza.
  • Taura nachiremba kana wepanyama wezvekudzidzira kuita kana mwana wako achirwadziwa.

Vana vane kusuwa kana kutsamwa pamusoro pearthritis yavo vangangoda kutsigirwa.

Vamwe vana vane JIA vangangoda kuvhiyiwa, kusanganisira kutsiva kwemajoini.

Vana vane mashoma chete majoini akabatwa anogona kunge asina zviratidzo kwenguva yakareba.

Muvana vazhinji, chirwere ichi chinenge chisingashande uye chinokonzeresa kukuvara kwekubatana kudiki.

Kuomarara kwechirwere kunoenderana nenhamba yeanosangana majoini. Izvo hazviite kuti zviratidzo zvizoenda mune izvi zviitiko. Vana ava vanowanzo kuve nekurwadziwa kwenguva refu (kusingaperi), kuremara, uye matambudziko kuchikoro. Vamwe vana vanogona kuramba vaine arthritis sevanhu vakuru.

Zvinetso zvinogona kusanganisira:

  • Kupfeka kure kana kuparadzwa kwemajoini (kunogona kuitika kune vanhu vane zvakanyanya kukomba JIA)
  • Chinononoka mwero wekukura
  • Kukura kusina kukwana kweruoko kana gumbo
  • Kurasikirwa kwemaonero kana kuderera kwemaonero kubva kusingaperi uveitis (dambudziko iri rinogona kunge rakakomba, kunyangwe kana arthritis isina kunyanyisa)
  • Anemia
  • Kuzvimba kwakakomberedza moyo (pericarditis)
  • Yenguva refu (isingaperi) kurwadziwa, kusapinda chikoro zvakanaka
  • Macrophage activation syndrome, chirwere chakakomba chinogona kukura nehurongwa JIA

Fonera mupiki wako kana:

  • Iwe, kana mwana wako, cherekedza zviratidzo zveJIA
  • Zviratidzo zvinowedzera kuwedzera kana kusavandudza nemushonga
  • Zviratidzo zvitsva zvinokura

Iko hakuna kuzivikanwa kudzivirira kweJIA.

Vechidiki rheumatoid arthritis (JRA); Juvenile chisingaperi polyarthritis; Zvichiri hosha; Wechidiki spondyloarthritis

Beukelman T, Nigrovic PA. Juvenile idiopathic arthritis: zano iro nguva yaenda? J Rheumatol. 2019; 46 (2): 124-126. PMID: 30710000 www.ncbi.nlm.nih.gov/pubmed/30710000.

Nordal EB, Rygg M, Fasth A. Clinical maficha evechidiki idiopathic arthritis. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: chitsiko 107.

Ombrello MJ, Arthur VL, Zviyeuchidzo EF, et al.Maumbirwo eGenetic anosiyanisa systemic vechidiki idiopathic arthritis kubva kune mamwe marudzi evechidiki idiopathic arthritis: kiriniki uye yekurapa zvinoreva. Ann Rheum Dis. 2017; 76 (5): 906-913. PMID: 27927641 www.ncbi.nlm.nih.gov/pubmed/27927641.

Ringold S, Weiss PF, Beukelman T, uye al. 2013 yekugadziriswa kweiyo 2011 American College yeRheumatology kurudziro yekurapa kwevechidiki idiopathic arthritis: kurudziro yekurapwa kwevana vane systemic vechidiki idiopathic arthritis uye tibhii kuongororwa pakati pevana vanogamuchira biologic mishonga. Arthritis Rheum. 2013; 65 (10): 2499-2512. PMID: 24092554 www.ncbi.nlm.nih.gov/pubmed/24092554.

Schulert GS, Minoia F, Bohnsack J, uye al. Mhedzisiro yeiyo biologic kurapa pakiriniki uye murabhoritari maficha e macrophage activation syndrome inosanganisirwa nehurongwa hwevechidiki idiopathic arthritis. Arthritis Kuchengeta Res (Hoboken). 2018; 70 (3): 409-419. PMID: 28499329 www.ncbi.nlm.nih.gov/pubmed/28499329.

Ter Haar NM, van Dijkhuizen EHP, Swart JF, et al. Kurapa kunongedza uchishandisa recombinant interleukin-1 receptor antagonist seyekutanga-mutsara monotherapy mune nyowani-kutanga systemic vechidiki idiopathic arthritis: mhedzisiro kubva kumakore mashanu ekutevera-ekudzidza. Arthritis Rheumatol. 2019; 71 (7): 1163-1173. PMID: 30848528 www.ncbi.nlm.nih.gov/pubmed/30848528.

Wu EY, Rabinovich CE. Wechidiki idiopathic arthritis. Mune: Kliegman RM, St. Geme JW, Schor NF, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chap 180.

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