Kupindirana nephritis

Interstitial nephritis chirwere cheitsvo umo nzvimbo dziri pakati peitsvo tubules dzinozvimba (kupisa). Izvi zvinogona kukonzera matambudziko nemashandiro anoita itsvo dzako.

Interstitial nephritis inogona kunge iri yenguva pfupi (yakaoma), kana inogona kuramba ichigara (isingagumi) uye ichiwedzera kuwedzera nekufamba kwenguva.

Iyo yakaoma fomu yemukati nephritis inowanzo kukonzerwa nemhedzisiro yemimwe mishonga.

Izvi zvinotevera zvinogona kukonzera kupindirana nephritis:

• Allergic reaction kune chinodhaka (acute interstitial allergic nephritis).
• Autoimmune kusagadzikana, senge antitubular yepasi membrane membrane chirwere, chirwere cheKawasaki, Sjögren syndrome, systemic lupus erythematosus, kana granulomatosis ine polyangiitis.
• Zvirwere.
• Kushandiswa kwenguva refu kwemishonga yakadai seacetaminophen (Tylenol), aspirin, uye nonsteroidal anti-inflammatory drug (NSAIDs). Izvi zvinonzi analgesic nephropathy.
• Kurutivi mhedzisiro yemamwe maantibhakitiriya akadai sepenicillin, ampicillin, methicillin, uye sulfonamide mishonga.
• Kurutivi mhedzisiro yemimwe mishonga yakadai seye furosemide, thiazide diuretics, omeprazole, triamterene, uye allopurinol.
• Diki potasium muropa rako.
• Yakawandisa calcium kana uric acid muropa rako.

Kupindirana nephritis kunogona kukonzera zvinyoro kusvika kune zvakakomba zvinetso zveitsvo, kusanganisira zvakakomba itsvo kutadza. Munenge hafu yezviitiko, vanhu vanenge vadzikisa weti kubuda uye zvimwe zviratidzo zveakanyanya itsvo kutadza.

Zviratidzo zveichi chiitiko zvinogona kusanganisira:

• Ropa mune weti
• Kupindwa nechando
• Yakawedzera kana yakaderera weti kubuda
• Mamiriro epfungwa anochinja (kukotsira, kuvhiringidzika, koma)
• Nausea, kurutsa
• Mapundu
• Kuzvimba kwenzvimbo ipi neipi yemuviri
• Kurema huremu (kubva pakuchengeta fluid)

Anopa hutano anoita bvunzo dzepanyama. Izvi zvinogona kuratidza:

• Mapapu asina kujairika kana moyo unonzwika
• Kuwedzera kweropa
• Fluid mumapapu (pulmonary edema)

Kwakajairwa bvunzo dzinosanganisira:

• Arterial eropa magasi
• Ropa kemisitiri
• BUN uye neropa creatinine mazinga
• Yakazara kuverenga ropa
• Itsvo biopsy
• Itsvo Ultrasound
• Kuongorora urinal

Kurapa kunoenderana nechinokonzera dambudziko. Kudzivisa mishonga inotungamira kune ino mamiriro kunogona kukurumidza kubvisa zviratidzo.

Kudzikamisa munyu uye mvura mukati mechikafu kunogona kusimudzira kuzvimba uye neBP. Kuderedza mapuroteni mune chikafu kunogona kubatsira kudzora kuwanda kwemarara muropa (azotemia), izvo zvinogona kutungamira kuzviratidzo zveakanyanya itsvo kutadza.

Kana dialysis ichidikanwa, inowanzodiwa kwenguva pfupi chete.

Corticosteroids kana yakasimba mishonga inorwisa kuzvimba yakadai secyclophosphamide dzimwe nguva inogona kubatsira.

Kazhinji kazhinji, interstitial nephritis chirwere chenguva pfupi. Muzviitiko zvisingawanzoitika, zvinogona kukonzera kukuvara kusingaperi, kusanganisira kwenguva refu (kusingaperi) itsvo kutadza.

Acute interstitial nephritis inogona kuve yakanyanya uye inogona kutungamira kukuvara kwenguva refu kana kusingaperi kweitsvo muvanhu vakura.

Metabolic acidosis inogona kuitika nekuti itsvo hadzikwanise kubvisa acid yakakwana. Iyo kusagadzikana kunogona kutungamira kune yakaoma kana isingagumi itsvo kutadza kana yekupedzisira-nhanho chirwere cheitsvo.

Fonera waunopa kana iwe uine zviratidzo zveiyo interstitial nephritis.

Kana iwe uine interstitial nephritis, fonera mupi wako kana iwe ukawana zviratidzo zvitsva, kunyanya kana usiri wakangwarira kana uine kuderera kwekuburitsa weti.

Kazhinji, kusagadzikana hakugone kudzivirirwa. Kudzivisa kana kudzikisa mashandisiro ako emishonga inogona kukonzera mamiriro aya kunogona kubatsira kudzikisa njodzi yako. Kana zvichidikanwa, mupi wako anokuudza iwe kuti ndeapi mishonga yekumisa kana kudzikisa.

Tubulointerstitial nephritis; Nephritis - yemukati; Acute kupindirana (sema) nephritis

• Itsvo anatomi

Neilson EG. Tubulointerstitial nephritis. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 122.

Perazella MA, Rosner MH. Zvirwere zveTubulointerstitial. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 10th ed. Philadelphia, PA: Elsevier; 2020: chits. 35.

Tanaka T, Nangaku M. Chisingaperi interstitial nephritis. Muna: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Yakakwana Kliniki Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 62.