Yakareba renal tubular acidosis

Distal renal tubular acidosis chirwere chinoitika kana itsvo dzisinganyatso bvisa acid kubva muropa kuenda mumurini. Nekuda kweizvozvo, acid yakawandisa inoramba iri muropa (inonzi acidosis).

Kana muviri ukaita mashandiro awo akajairika, unoburitsa acid. Kana iyi acid ikasabviswa kana kurerutswa, ropa rinova rakawandisa. Izvi zvinogona kutungamira mukusaenzana kwe electrolyte muropa. Inogona zvakare kukonzera matambudziko neyakajairika mashandiro emamwe maseru.

Itsvo dzinobatsira kudzora mwero weasidhi yemuviri nekubvisa asidhi muropa uye nekuiburitsa mukati merini.

Distal renal tubular acidosis (mhando I RTA) inokonzerwa nehurema mune itsvo machubhu ayo anokonzera asidhi kuvaka muropa.

Type I RTA inokonzerwa nemhando dzakasiyana dzemamiriro, kusanganisira:

• Amyloidosis, iyo yakavaka mapuroteni asina kujairika, anonzi amyloid, mumatumbu uye nhengo
• Fabry chirwere, chisina kujairika anovakwa mumuviri weimwe mhando yemafuta chinhu
• Yakakwira mwero wecalcium muropa
• Sickle cell chirwere, masero matsvuku eropa ayo anowanzo kuve akaumbwa sedisk anotora jeko kana chimiro checrescent
• Sjögren syndrome, autoimmune kusagadzikana umo maronda anounza misodzi uye mate anoparadzwa
• Systemic lupus erythematosus, chirwere chinodzivirira muviri umo immune system inorwisa zvisirizvo zvinyama zvine hutano
• Chirwere cheWilson, chirwere chinogarwa nhaka umo mune mhangura yakawandisa mumatumbu emuviri
• Kushandiswa kwemimwe mishonga, yakadai seamphotericin B, lithium, uye analgesics

Zviratidzo zve distal renal tubular acidosis zvinosanganisira chero cheanotevera:

• Kuvhiringidzika kana kudzikira kwekusvinura
• Kuneta
• Kukanganisika kukura muvana
• Kuwedzera mweya wekufema
• Itsvo matombo
• Nephrocalcinosis (yakawandisa calcium yakaiswa muitsvo)
• Osteomalacia (kupfavisa kwemapfupa)
• Tsvina kushaya simba

Zvimwe zviratidzo zvinogona kusanganisira:

• Kurwadziwa kwepfupa
• Yakaderera weti kubuda
• Yakawedzera kurova kwemoyo kana kusagadzikana kwemoyo
• Tsandanyama tsandanyama
• Marwadzo kumashure, kuruboshwe, kana dumbu
• Skeletal kusagadzikana

Anopa hutano anoita bvunzo dzepanyama uye obvunza nezve zviratidzo zvako.

Miedzo inogona kurairwa inosanganisira:

• Arterial ropa gasi
• Ropa kemisitiri
• Weti pH
• Acid-mutoro bvunzo
• Bicarbonate infusion bvunzo
• Kuongorora urinal

Calcium inoisa muitsvo uye itsvo mabwe anogona kuoneka pane:

• X-ray
• Ultrasound
• CT scan

Icho chinangwa ndechekudzosera zvakajairwa acid nhanho uye muyero we electrolyte mumuviri. Izvi zvinobatsira kugadzirisa kusagadzikana kwemapfupa uye kuderedza calcium kuvaka muitsvo (nephrocalcinosis) nematombo eitsvo.

Icho chinokonzera chikonzero che distal renal tubular acidosis chinofanira kugadziriswa kana ichigona kuzivikanwa.

Mishonga inogona kupihwa inosanganisira potassium citrate, sodium bicarbonate, uye thiazide diuretics. Iyi ndiyo mishonga yealkali inobatsira kugadzirisa acidic mamiriro emuviri. Sodium bicarbonate inogona kugadzirisa kurasikirwa kwe potassium uye calcium.

Dambudziko racho rinofanirwa kurapwa kudzikisa mhedzisiro yaro uye kusagadzikana, izvo zvinogona kugara zvachose kana kutyisidzira hupenyu. Mazhinji kesi anova nani nekurapwa.

Fonera mupi wako kana iwe uine zviratidzo zve distal renal tubular acidosis.

Wana rubatsiro rwechiremba ipapo ipapo kana iwe ukava nezviratidzo zvechimbichimbi zvakaita se:

• Kuderera kwekuziva
• Kufenda
• Kuderera kwakanyanya mukusvinura kana kutarisa

Iko hakuna kudzivirira kweichi chirwere.

Renal tubular acidosis - distal; Renal tubular acidosis mhando I; Tora I RTA; RTA - distal; Classical RTA

• Itsvo anatomi
• Itsvo - kuyerera kweropa uye weti

Bushinsky DA. Itsvo matombo. Mune: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Chinyorwa cheEndocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: chits. 32.

Dixon BP. Renal tubular acidosis. Mune: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsiko 547.

Seifter JL. Acid-base kusagadzikana. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 110.