Waterhouse-Friderichsen chirwere

Waterhouse-Friderichsen syndrome (WFS) iboka rezviratidzo zvinokonzerwa nekukundikana kwematenal adrenal kushanda zvakajairika semhedzisiro yekubuda ropa mugland.

Idzo adrenal gland idiki mbiri dzakaumbwa-katatu. Imwe gland iri pamusoro petsvo imwe neimwe. Iyo adrenal glands inogadzira uye inosunungura mahormone akasiyana ayo muviri unoda kushanda zvakajairika. Iyo adrenal gland inogona kukanganiswa nezvirwere zvakawanda, senge hutachiona seWFS.

WFS inokonzerwa nehutachiona hwakakomba ne meningococcus bacteria kana mamwe mabhakitiriya, akadai se:

• Boka B streptococcus
• Pseudomonas aeruginosa
• Streptococcus pneumoniae
• Staphylococcus aureus

Zviratidzo zvinoitika kamwe kamwe. Izvo zvinokonzerwa nehutachiona huri kukura (kuwanda) mukati memuviri. Zviratidzo zvinosanganisira:

• Fivha uye kutonhora
• Joint uye mhasuru kurwadziwa
• Kutemwa nemusoro
• Kusvipa

Kubatira hutachiona kunokonzera kubuda ropa mumuviri wese, izvo zvinokonzeresa:

• Kuputika kwemuviri wese
• Yakaparadzirwa intravascular coagulation umo mashoma eropa anovhara akacherera ropa kunhengo
• Sepic kuvhunduka

Kubuda ropa mukati meadrenal glands kunokonzeresa adrenal dambudziko, mairi yakakwana adrenal mahormoni haina kugadzirwa. Izvi zvinotungamira kuzviratidzo zvakaita se:

• Dzungu, kushaya simba
• Yakanyanya yakaderera BP
• Yakanyanya kukurumidza kurova kwemoyo
• Kuvhiringidzika kana kukoma

Anopa hutano anozoongorora muviri uye obvunza nezve zviratidzo zvemunhu.

Kuongororwa kweropa kuchaitwa kuratidza hutachiona hutachiona. Miedzo inogona kusanganisira:

• Tsika yeropa
• Yakazara kuverenga kweropa nemusiyano
• Dzidzo yekuvhara ropa

Kana mupi achifungidzira kuti hutachiona hunokonzerwa ne meningococcus bacteria, mimwe bvunzo inogona kuitwa inosanganisira:

• Lumbar kubaya kuti utore sampu yemuzongoza mvura yetsika
• Ganda biopsy uye Gram stain
• Weti kuongorora

Miedzo inogona kurairwa kuti ibatsire kuongorora yakaoma adrenal dambudziko inosanganisira:

• ACTH (cosyntropin) kukurudzira bvunzo
• Cortisol kuongororwa kweropa
• Ropa shuga
• Potassium ropa bvunzo
• Kuongororwa kweropa reSodium
• Ropa pH bvunzo

Mishonga inorwisa mabhakitiriya inotangwa ipapo kurapa hutachiona. Mishonga yeGlucocorticoid ichapihwawo kurapa kushomeka kwedhizizi. Anotsigira marapirwo anozodiwa kune zvimwe zviratidzo.

WFS inouraya kunze kwekunge kurapwa kwehutachiona hutachiona kwatanga ipapo uye glucocorticoid zvinodhaka zvinopihwa.

Kudzivirira WFS inokonzerwa ne meningococcal bacteria, mushonga unowanikwa.

Fulminant meningococcemia - Waterhouse-Friderichsen chirwere; Fulminant meningococcal sepsis - Waterhouse-Friderichsen syndrome; Hemorrhagic adrenalitis

• Meningococcal maronda kumashure
• Adrenal gland hormone kuchengetedzwa

Stephens DS. Neisseria meningitides. Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier Saunders; 2020: chitsama 211.

Newell-Mutengo JDC, Auchus RJ. Iyo adrenal cortex. Mune: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Chinyorwa cheEndocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: chits. 15.