Meningitis - cryptococcal

Cryptococcal meningitis chirwere chefungal chemasuru anovhara uropi uye musana. Nyama idzi dzinonzi mamenji.

Muzviitiko zvakawanda, cryptococcal meningitis inokonzerwa nefungus Cryptococcus neoformans. Iyi fungus inowanikwa muvhu kutenderera pasirese. Cryptococcus gattii inogona zvakare kukonzera meningitis, asi fomu iri rinogona kukonzera chirwere muvarwere vane zvakajairika immune system zvakare.

Rudzi urwu rwechirwere chemumuzongoza harupararire kubva kumunhu kuenda kumunhu. Kazhinji, inopararira kuburikidza neropa kuenda kuuropi kubva kune imwe nzvimbo mumuviri une hutachiona.

Cryptococcus neoformans meningitis inowanzo bata vanhu vane immune system isina kusimba, kusanganisira vanhu vane:

• AIDS
• Cirrhosis (rudzi rwechiropa chirwere)
• Chirwere cheshuga
• Leukemia
• Lymphoma
• Sarcoidosis
• Nhengo yekuisa

Chirwere ichi hachiwanzoitika kune vanhu vane immune system uye vasina matambudziko ehutano kwenguva refu.

Iyi fomu ye meningitis inotanga zvishoma, pamusoro pemazuva mashoma kusvika kumavhiki mashoma. Zviratidzo zvinogona kusanganisira:

• Kupindwa nechando
• Hallucinations
• Kutemwa nemusoro
• Pfungwa chinzvimbo chinja (nyonganiso
• Kusvotwa uye kurutsa
• Kunzwisisa kuchiedza
• Mutsipa wakaoma

Anokupa hutano anozokuongorora obvunza nezvezviratidzo zvako.

Lumbar puncture (musana tap) inoshandiswa kuongorora chirwere chengono. Mumuedzo uyu, sampu yecebrospinal fluid (CSF) inobviswa kubva mumuzongoza wako uye kuyedzwa.

Mimwe bvunzo inogona kuitwa inosanganisira:

• Tsika yeropa
• Chest x-ray
• Cryptococcal antigen muCSF kana ropa, kutsvaga masoja ekudzivirira chirwere
• CSF kuongororwa kwesero kuverenga, glucose, uye mapuroteni
• CT scan yemusoro
• Gram stain, mamwe akasviba mavara, uye tsika yeCSF

Antifungal mishonga inoshandiswa kurapa fomu iri remumuzongoza. Intravenous (IV, kuburikidza nemutsinga) kurapa neamphotericin B ndiyo yekurapa kwakanyanya. Inowanzo sanganiswa nemumuromo antifungal mushonga unonzi 5-flucytosine.

Mumwe wemumuromo mushonga, fluconazole, mune yakakwira madhizaini anogona zvakare kuve anoshanda. Kana zvichidikanwa, ichave yakatemwa gare gare mune yechirwere kosi.

Vanhu vanopora kubva kune cryptococcal meningitis vanoda mishonga yenguva refu yekudzivirira hutachiona kuti hurege kudzoka. Vanhu vane immune immune isina kusimba, sevaya vane HIV / AIDS, vanozodawo kurapwa kwenguva refu kusimudzira immune yavo.

Aya matambudziko anogona kuitika kubva kuhutachiona.

• Kukuvara kwehuropi
• Kunzwa kana kurasikirwa kurasikirwa
• Hydrocephalus (yakawandisa CSF muuropi)
• Kufenda
• Rufu

Amphotericin B inogona kuve nemhedzisiro senge:

• Kusvotwa uye kurutsa
• Fivha uye kutonhora
• Joint uye mhasuru aches
• Itsvo kukuvara

Fonera yako yemuno emergency emergency (se911) kana iwe ukaita chero eakakomba ezviratidzo akanyorwa pamusoro. Meningitis inogona kukurumidza kuve chirwere chinotyisa.

Fonera yako yemuno emergency emergency kana kuenda kune yekukurumidza emergency imba kana iwe uchifungidzira meningitis mumwana mudiki ane izvi zviratidzo:

• Kudyisa matambudziko
• Kuchema kwepamusoro
• Kushatirwa
• Kuramba uchirarama, isingatsanangurike fivha

Cryptococcal yomumuzongoza

• Central nervous system uye yekumusoro tsinga system

Nzvimbo dzekuchengetedza Dziviriro uye Kudzivirira webhusaiti. Fungal yomumuzongoza. www.cdc.gov/meningitis/fungal.html. Yakagadziridzwa Nyamavhuvhu 06, 2019. Yakasvika muna Kukadzi 18, 2021.

Kauffman CA, Chen S. Cryptococcosis. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 317.

Yakakwana JR. Cryptococcosis (Cryptococcus neoformans uye Cryptococcus gattii). Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 262.