Akawanda system atrophy - cerebellar subtype

Multiple system atrophy - cerebellar subtype (MSA-C) chirwere chisingawanzo chinokonzera nzvimbo dzakadzika muuropi, pamusoro pemutsipa wepelinha, kudzikira (atrophy). MSA-C yaimbozivikanwa seolivopontocerebellar atrophy (OPCA).

MSA-C inogona kupfuudzwa pasi kuburikidza nemhuri (nhaka fomu). Iyo inogona zvakare kukanganisa vanhu vasina inozivikanwa mhuri nhoroondo (zvisingaite fomu).

Vatsvakurudzi vakaona mamwe majini anowanikwa mune zvakagara nhaka zvemamiriro aya.

Chikonzero cheMSA-C muvanhu vane fomu inowanzoitika hachizivikanwe. Hosha inononoka kuwedzera (iri kufambira mberi).

MSA-C inowanzoitika zvakanyanya kune varume kupfuura vakadzi. Avhareji zera rekutanga ane makore makumi mashanu nemana ekuberekwa.

Zviratidzo zveMSA-C zvinotanga kutanga pazera diki kune vanhu vane fomu rakagarwa nhaka. Chiratidzo chikuru kusagadzikana (ataxia) iyo inowedzera kuwedzera. Panogona zvakare kuve nematambudziko nekudzikama, slurring yekutaura, uye kunetsekana kufamba.

Zvimwe zviratidzo zvinogona kusanganisira:

• Kufambisa kwemaziso kusingaite
• Kufamba kusingaite
• Matambudziko emuura kana chedundira
• Zvakaoma kumedza
• Maoko anotonhora nemakumbo
• Musoro wakareruka kana wakamira
• Kutemwa nemusoro wakamira izvo zvinonunurwa nekurara pasi
  
• Kuomesa kwemhasuru kana kuomarara, kutsemuka, kudedera
• Kukuvara kwemitsipa (neuropathy)
• Zvinetso mukutaura uye pakurara nekuda kwekukakavara kwenzwi tambo
• Zvepabonde basa matambudziko
• Kudikitira zvisina kujairika

Kuongororwa kwakakwana kwehurapi uye hunyanzvi system, pamwe nekuongorora chiratidzo uye nhoroondo yemhuri zvinodiwa kuti kuongororwa.

Kune bvunzo dzekuberekwa kutsvaga zvikonzero zvemamwe marudzi echirwere. Asi, hapana chaiyo bvunzo inowanikwa mune dzakawanda kesi. Iyo MRI yeuropi inogona kuratidza shanduko muhukuru hweanokanganisa masisitimu ehuropi, kunyanya chirwere ichi chichiwedzera. Asi zvinokwanisika kuve nechavharo uye uine yakajairika MRI.

Mimwe bvunzo senge positron emission tomography (PET) inogona kuitwa kutonga mamwe mamiriro. Izvi zvinogona kusanganisira kumedza zvidzidzo kuti uone kana munhu achikwanisa kumedza chikafu uye mvura zvakachengeteka.

Iko hakuna chaiyo kurapwa kana kurapwa kweMSA-C. Chinangwa ndechekurapa zviratidzo uye kudzivirira kunetseka. Izvi zvinogona kusanganisira:

• Kudedera mishonga, yakadai seiya yechirwere cheParkinson
• Kutaura, kurapwa uye kurapa kwemuviri
• Nzira dzekudzivirira kudzipwa
• Yekubatsira yekubatsira ine mwero uye kudzivirira kuwira

Aya mapoka anotevera anogona kupa zviwanikwa uye rutsigiro kune vanhu vane MSA-C:

• Kukunda MSA Mubatanidzwa - conqumsa.org/patient-programs/
• Iyo MSA Coalition - www.multiplesystematrophy.org/msa-resource/

MSA-C inowedzera kuwedzera, uye hapana mushonga. Maonero acho kazhinji haana kunaka. Asi, zvinogona kutora makore mumwe munhu asati aremara zvakanyanya.

Zvinetso zveMSA-C zvinosanganisira:

• Choking
• Utachiona kubva mukufema chikafu mumapapu (aspiration pneumonia)
• Kukuvara kubva kudonha
• Zvinetso zvinovaka muviri nekuda kwekunetseka kumedza

Fonera wako mupi wezvehutano kana iwe uine chero zviratidzo zveMSA-C. Iwe unozofanirwa kuonekwa nachiremba wezveuropi. Uyu chiremba anobata matambudziko ehurongwa hwemitsipa.

MSA-C; Cerebellar yakawanda system atrophy; Olivopontocerebellar atrophy; OPCA; Olivopontocerebellar kudzikira

• Central nervous system uye yekumusoro tsinga system

Ciolli L, Krismer F, Nicoletti F, Wenning GK. Iyo yekuvandudza pane iyo cerebellar subtype yeakawanda system atrophy. Cerebellum Ataxias. 2014; 1-14. PMID: 26331038 pubmed.ncbi.nlm.nih.gov/26331038/.

Gilman S, Wenning GK, Yakadzika PA, et al. Chechipiri chibvumirano chekubvumirana nezve kuongororwa kweakawanda system atrophy. Neurology. 2008; 71 (9): 670-676. PMID: 18725592 pubmed.ncbi.nlm.nih.gov/18725592/.

Jancovic J. Parkinson chirwere uye zvimwe zvinetso zvekufamba. Mune: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology muClinical Dzidzira. 7th ed. Philadelphia, PA: Elsevier; 2016: chits. 96.

Ma MJ. Biopsy pathology ye neurodegenerative kusagadzikana muvakuru. Mune: Perry A, Brat DJ, eds. Anoshanda Okuvhiya Neuropathology: Iyo Yekuongorora Nzira. 2nd ed. Philadelphia, PA: Elsevier, 2018: chitsiko 27.

Walsh RR, Krismer F, Galpern WR, uye al. Kurudziro yepasirese akawanda system atrophy yekutsvaga nzira yemusangano. Neurology. 2018; 90 (2): 74-82. PMID: 29237794 pubmed.ncbi.nlm.nih.gov/29237794/.