Neurofibromatosis 2

Neurofibromatosis 2 (NF2) chirwere umo mamota anoumba pamitsipa yeuropi uye musana (iyo yepakati tsinga system). Inopfuudzwa pasi (nhaka) mumhuri.

Kunyangwe iine zita rakafanana neiyo neurofibromatosis mhando 1, iri rakasiyana uye rakaparadzana mamiriro.

NF2 inokonzerwa nekuchinja mune gene NF2. NF2 inogona kupfuudzwa pasi kuburikidza nemhuri mune ye autosomal yakanyanya pateni. Izvi zvinoreva kuti kana mumwe mubereki aine NF2, chero mwana wemubereki iyeye ane 50% mukana wekugara nhaka mamiriro acho. Zvimwe zviitiko zveNF2 zvinoitika apo geni rinochinja roga. Kana mumwe munhu akatakura shanduko yemajini, vana vavo vane mukana we50% wekugara nhaka.

Chinhu chikuru chengozi kuve nenhoroondo yemhuri yemamiriro acho.

Zviratidzo zveNF2 zvinosanganisira:

• Matanho epakati
• Kurwara achiri mudiki
• Shanduko muchiono
• Kofi-mavara mavara paganda (café-au-lait), isingawanzo kujairika
• Kutemwa nemusoro
• Kunzwa kurasikirwa
• Kurira uye ruzha munzeve
• Kushaya simba kwechiso

Zviratidzo zveNF2 zvinosanganisira:

• Uropi uye mapundu emusana
• Kunzwa-zvine hukama (acoustic) mamota
• Mamota eganda

Miedzo inosanganisira:

• Kuongorora kwepanyama
• Nhoroondo yezvechiremba
• MRI
• CT scan
• Kuongorora genetic

Acoustic tumors inogona kucherechedzwa, kana kurapwa nekuvhiyiwa kana radiation.

Vanhu vane chirwere ichi vanogona kubatsirwa kubva kumaricho ekupa mazano.

Vanhu vane NF2 vanofanirwa kuongororwa nguva dzese nemiyedzo iyi:

• MRI yeuropi uye musana
• Kunzwa uye kuongorora kwehurukuro
• Kuongorora kwemaziso

Izvi zvinotevera zviwanikwa zvinogona kupa rumwe ruzivo paNF2:

• Yevana Tumor Foundation - www.ctf.org
• Neurofibromatosis Network - www.nfnetwork.org

NF2; Bilateral acoustic neurofibromatosis; Bilateral vestibular schwannomas; Central neurofibromatosis

• Central nervous system uye yekumusoro tsinga system

Sahin M, Ullrich N, Srivastava S, Pinto A. Neurocutaneous syndromes. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsiko 614.

Slattery WH. Neurofibromatosis 2. Muna: Brackmann DE, Shelton C, Arriaga MA, eds. Kuvhiya kweOtologic. 4th ed. Philadelphia, PA: Elsevier; 2016: chits. 57.

Varma R, Williams SD. Neurology. Mune: Zitelli BJ, McIntire SC, Nowalk AJ, eds. Zitelli naDavis 'Atlas yePediatric Panyama Kuongorora. 7th ed. Philadelphia, PA: Elsevier; 2018: chits.