Autosomal yakawandisa

Autosomal recessive ndeimwe yenzira dzinoverengeka idzo hunhu, kusagadzikana, kana chirwere chinogona kupfuudzwa kuburikidza nemhuri.

Autosomal recessive disorder inoreva kuti ma kopi maviri eakajairika geni anofanirwa kuve aripo kuitira kuti chirwere kana hunhu kukura.

Kugara nhaka chimwe chirwere, chimiro, kana hunhu zvinoenderana nerudzi rwechromosome iyo inobatika. Mhando mbiri idzi ndedze autosomal chromosomes uye dzepabonde chromosomes. Izvo zvakare zvinoenderana nekuti hunhu hwacho hukuru here kana kuti hwakawandisa.

Shanduko mune geni pane imwe yekutanga makumi maviri nemaviri nonsex chromosomes inogona kutungamira kune autosomal kusagadzikana.

Majini anouya ari maviri. Rimwe jeni mune rimwe nerimwe rinouya kubva kuna amai, uye rimwe jeni rinobva kuna baba. Kudzokorora nhaka kunoreva kuti mageneti maviri ari maviri anofanira kunge asina kujairika kukonzera chirwere. Vanhu vane rimwe chete geni rakaremara mune vaviri vanonzi vatakuri.Vanhu ava kazhinji havana kukanganiswa nemamiriro acho. Nekudaro, ivo vanokwanisa kupfuudza zvisina kujairika geni kuvana vavo.

Mikana yekugara nhaka tsika

Kana iwe wakazvarwa kune vabereki vane vese vane imwechete autosomal yakawandisa geni, iwe une 1 mu4 mukana wekugara nhaka isina kujairika geni kubva kune vese vabereki uye nekuvandudza chirwere. Iwe une 50% (1 mu2) mukana wekugara nhaka imwe isina kujairika geni. Izvi zvaigona kukuita mutakuri.

Mune mamwe mazwi, kumwana akazvarwa kune vaviri vaviri vakatakura geni (asi vasina zviratidzo zvehosha), mhedzisiro inotarisirwa kune imwe nhumbu ndeiyi:

• Mukana we25% wekuti mwana akazvarwa aine magene maviri akajairika (zvakajairika)
• Mukana we50% wekuti mwana azvarwe aine yakajairwa uye rimwe geni risina kujairika (anotakura, asina chirwere)
• Mukana we25% wekuti mwana akazvarwa aine maviri asina kujairika majini (ari panjodzi yechirwere)

Ongorora: Izvi zvabuda hazvireve kuti vana vanozotakura kana kukuvadzwa zvakanyanya.

Genetics - autosomal yakawandisa; Nhaka - autosomal yakawandisa

• Autosomal yakawandisa
• X-yakabatanidzwa yakawandisa majini kukanganisa
• Genetics

Feero WG, Zazove P, Chen F. Clinical genomics. Mune: Rakel RE, Rakel DP, eds. Chinyorwa cheMhuri Mishonga. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 43.

Gregg AR, Kuller JA. Yemunhu genetics uye mapatani enhaka. Mu: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Sirivha RM, eds. Creasy uye Resnik's Maternal-Fetal Mushonga: Misimboti uye Dzidzira. 8th ed. Philadelphia, PA: Elsevier; 2019: chits. 1.

Korf BR. Nheyo dze genetics. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 35.