Virilization

Virilization mamiriro ezvinhu apo mukadzi anokudziridza hunhu hunobatanidzwa nemahomoni echirume (androgens), kana kana mwana achangozvarwa aine hunhu hwehormone yemurume pakuberekwa.

Virilization inogona kukonzerwa ne:

• Kuwedzera testosterone kugadzirwa
• Kushandiswa kweanabolic steroid (kuita-kusimudzira kana zvine chekuita nekupihwa patsva)

Mune vakomana vachangoberekwa kana vasikana, mamiriro acho anogona kukonzerwa ne:

• Mimwe mishonga inotorwa naamai panguva yepamuviri
• Kuberekwa adrenal hyperplasia mumucheche kana amai
• Zvimwe zvehutano mune amai (senge mamota emaovari kana adrenal gland anosunungura mahormone echirume)

Mune vasikana vari kuyaruka, mamiriro acho anogona kukonzerwa ne:

• Polycystic ovary chirwere
• Mimwe mishonga, kana anabolic steroids
• Kuberekwa adrenal hyperplasia
• Mamota emazai, kana adrenal glands anosunungura mahormone echirume (androgens)

Mune vakadzi vakuru, mamiriro acho anogona kukonzerwa ne:

• Mimwe mishonga, kana anabolic steroids
• Tumota dzemazai kana adrenal gland anosunungura mahormone echirume

Zviratidzo zve virilization mune mukadzi zvinowanzoenderana padanho re testosterone mumuviri.

Chikamu chakadzika (chakajairika):

• Rakakora, rakasviba kumeso bvudzi mune ndebvu kana nzvimbo yemastache
• Wedzera bvudzi remuviri
• Ganda rine mafuta kana acne
• Nguva dzisina kumwedzi dzekuenda kumwedzi

Moderate level (zvisingawanzoitika):

• Mhanza yemurume
• Kurasikirwa kwekuparadzirwa kwemafuta echikadzi
• Kuderedza kukura kwemazamu

Chikamu chepamusoro (chisingawanzoitika):

• Kuwedzera kwechikorisiti
• Kudzika kwezwi
• Semurume mhasuru pateni

Miedzo inogona kusanganisira:

• Ropa bvunzo kuti uone yakawandisa testosterone muvakadzi
• CT scan, MRI, kana ultrasound kutonga kunze kwemamota emazai uye adrenal glands

Kana virilization ichikonzerwa nekuratidzwa kune uyerogen (echirume mahormone) mune vakadzi vakuru, mazhinji ezviratidzo anoenda kana mahormone amiswa. Nekudaro, kudzika kwezwi chiitiko chinogara chiripo chekuratidzwa kune androgens.

• Hypothalamus kugadzirwa kwehomoni

Gooren LJ. Iyo endocrinology yehunhu hwepabonde uye kuzivikanwa kwechikadzi. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 124.

Styne DM, Grumbach MM. Physiology uye kusagadzikana kwekuyaruka. Mune: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Chinyorwa cheEndocrinology. 13 ed. Philadelphia, PA: Elsevier; 2016: chits. 25.