Munyori: Gregory Harris
Zuva Rekusika: 7 Kubvumbi 2021
Gadziridza Zuva: 20 Mbudzi 2024
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Kuteedzera chikamu chechina ndeye kuyerwa kweropa kunoyera chiitiko cheimwe protein. Iyi protein chikamu cheyunisheni system. Iyo complement system iboka remaprotein anosvika makumi matanhatu anowanikwa muplasma yeropa kana pamusoro pemamwe maseru.

Mapuroteni anoshanda nema immune system ako uye anoita basa mukudzivirira kubva kuhutachiona. Dzinobatsirawo kubvisa masero akafa uye zvekune dzimwe nyika kubva mumuviri. Kazhinji, vanhu vanogona kugara nhaka kushomeka kwevamwe vanozadzisa mapuroteni. Vanhu ava vanowanzo tenderwa nezvimwe hutachiona kana autoimmune kusagadzikana.

Iko kune mapfumbamwe makuru ekuwedzera mapuroteni. Ivo vakanzi C1 kuburikidza neC9. Ichi chinyorwa chinotsanangura bvunzo inoyera C4.

Ropa rinotorwa kubva mutsinga. Tsinga kubva mukati megokora kana kuseri kweruoko inowanzo shandiswa.

Maitiro acho anotevera:

  • Iyo saiti inocheneswa neantiseptic.
  • Anopa hutano anomonera bhandi rakasunga paruoko rwekumusoro kuisa kumanikidza kunzvimbo uye kuita kuti tsinga izate neropa.
  • Mupi anopa zvinyoro nyoro tsono mukati mutsinga.
  • Ropa rinoungana mumudziyo usingavharike mweya kana chubhu yakasungirirwa mutsono. Iyo yakasununguka bhandi inobviswa kubva paruoko rwako.
  • Ropa parangounganidzwa, tsono inobviswa. Nzvimbo yekubaya yakavharwa kumisa chero kubuda ropa.

Mune vacheche kana vana vadiki, chishandiso chakapinza chinonzi lancet inogona kushandiswa kubaya ganda uye kuita kubuda ropa. Ropa rinoungana mutubhu tudiki girazi kanonzi pipette, kana panotsvedza kana bvunzo. Bhandeji rinogona kuiswa pamusoro penharaunda kana paine kubuda ropa.


Hapana gadziriro inokosha inodiwa.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanogona kungonzwa kubaya kana kuruma. Mushure meizvozvo, panogona kunge paine kurovera.

C3 neC4 ndizvo zvinowanzo kuyerwa zvinowedzeredza zvinhu. Kana iyo yekuwedzera system ikashandurwa panguva yekuzvimba, iwo mazinga ekutsigira mapuroteni anogona kudzikira. Kuteedzera chiitiko chinogona kuyerwa kuti uone kuti chirwere chakanyanya sei kana kurapwa kuri kushanda.

Chiyero chekuwedzera chinogona kushandiswa kuongorora vanhu vane autoimmune kusagadzikana. Semuenzaniso, vanhu vane inoshanda systemic lupus erythematosus vanogona kunge vaine yakaderera-kupfuura-yakajairwa mazinga eanowedzera mapuroteni C3 neC4.

Kuteedzera zviitiko zvinosiyana mumuviri wese. Mune vanhu vane rheumatoid arthritis, basa rekuwedzera rinogona kunge rakajairika kana rakakwira-kupfuura-rinowanzoitika muropa, asi rakanyanya kudzika-kupfuura-kwese mujoin fluid.

Kazhinji masendimita eC4 ane mamirigiramu gumi nemashanu kusvika makumi mashanu padhisilita (mg / dL) (0.15 kusvika 0.45 g / L).


Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Kuwedzera kwekuwedzera chiitiko kunoonekwa mu:

  • Gomarara
  • Ulcerative colitis

Kuderera kwekuwedzera chiitiko kunoonekwa mu:

  • Hutachiona hutachiona (kunyanya Neisseria)
  • Cirrhosis
  • Glomerulonephritis
  • Hepatitis
  • Nhaka angioedema
  • Itsvo kuisazve kurambwa
  • Lupus nephritis
  • Kushaya zvokudya zvinovaka muviri
  • Systemic lupus erythematosus
  • Kazhinji kugarwa kunowedzera kukwana

Njodzi dzakabatana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

  • Kuwedzera kubuda ropa
  • Kufenda kana kunzwa kushaya musoro
  • Hematoma (ropa rinoungana pasi peganda)
  • Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

C4


  • Kuongorora ropa

Holers VM. Komberedza uye ayo anogamuchira: hutsva hutsva muzvirwere zvevanhu. Annu Rev Immunol. 2014; 3: 433-459. PMID: 24499275 www.ncbi.nlm.nih.gov/pubmed/24499275.

Massey HD, McPherson RA, Huber SA, Jenny NS. Murevereri wekuzvimba: kuzadzisa. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chits. 47.

Morgan BP, Harris CL. Kwiridzira, chinangwa chekurapa muzvirwere zvinoputira uye zvinogumbura. Nat Rev Zvinodhaka Discov. 2015; 14 (2): 857-877. PMID: 26493766 www.ncbi.nlm.nih.gov/pubmed/26493766.

Merle NS, Chechi SE, Fremeaux-Bacchi V, Roumenina LT. Komberedza sisitimu chikamu I - mamorekuru maitiro ekumisikidza uye mutemo. Pamberi Immunol. 2015; 6: 262. PMID: 26082779 www.ncbi.nlm.nih.gov/pubmed/26082779.

Merle NS, Noe R, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT. Komberedza sisitimu chikamu II: basa rekuzvidzivirira. Pamberi Immunol. 2015; 6: 257. PMID: 26074922 www.ncbi.nlm.nih.gov/pubmed/26074922.

Sullivan KE, Grumach AS. Iyo yekuwedzera system. Mune: Adkinson NF, Bochner BS, Burks AW, et al, eds. Middleton's Allergy: Maitiro uye Maitiro. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014: chits.

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