Pyruvate kinase ropa bvunzo

Iyo pyruvate kinase bvunzo inoyera padanho reiyo enzyme pyruvate kinase muropa.

Pyruvate kinase ndiyo enzyme inowanikwa mumasero matsvuku eropa. Inobatsira kushandura shuga muropa (glucose) kune simba kana iwo oxygen mazinga akaderera.

Muenzaniso weropa unodiwa. Mu laboratori, masero machena eropa anobviswa kubva muropa nekuti anogona kuchinja mhedzisiro. Iyo nhanho ye pyruvate kinase inozoyerwa.

Hapana gadziriro yakakosha inodikanwa.

Kana mwana wako ari kuita bvunzo iyi, zvinogona kubatsira kutsanangura kuti bvunzo iyi ichanzwa sei uye kutaridza pachidhori. Tsanangura chikonzero chebvunzo. Kuziva iyo "sei uye nei" kunogona kudzora kushushikana kwemwana wako.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Bvunzo iyi inoitwa kuti uone yakadzika zvisina mwero nhanho ye pyruvate kinase. Pasina kukwana kweiyo enzyme, masero matsvuku eropa anoputsika nekukurumidza kupfuura zvakajairwa. Izvi zvinonzi hemolytic anemia.

Bvunzo iyi inobatsira kuongorora pyruvate kinase kushomeka (PKD).

Mhedzisiro inosiyana zvichienderana nenzira yekuyedza yakashandiswa. Muzhinji, kukosha kwakazara i179 ± 16 zviyuniti pa100 mL yemasero matsvuku eropa.

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nemupi wako wezvehutano nezve zvinorehwa nemimwe miedzo yako.

Iyo yakaderera chikamu che pyruvate kinase inosimbisa PKD.

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
• Hematoma (kuwanda kweropa pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Elghetany MT, Schexneider KI, Banki K. Erythrocytic kusagadzikana. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chits. 32.

Gallagher PG. Hemolytic anemias: red sero membrane uye metabolic kukanganisa. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 152.

Papachristodoulou D. Energy metabolism. Mu: Naish J, Syndercombe Dare D, eds. Chiremba Sayenzi. 3rd ed. Philadelphia, PA: Elsevier; 2019: chits. 3.

van Solinge WW, van Wijk R. Enzymes yesero tsvuku reropa. Mu: Rifai N, ed. Tietz Chinyorwa cheKiriniki Chemistry uye Molecular Diagnostics. 6th ed. Philadelphia, PA: Elsevier; 2018: chits.