Plasma amino acids

Plasma amino acids muyedzo wekuongorora unoitwa pane vacheche unotarisa huwandu hwemamino acids muropa. Amino acids ndiwo anovaka mapuroteni mumuviri.

Kazhinji yenguva, ropa rinotorwa kubva mutsinga iri mukati megokora kana kumashure kweruoko.

Mune vacheche kana vana vadiki, chishandiso chakapinza chinonzi lancet inogona kushandiswa kubaya ganda.

• Ropa rinoungana mutubhu tudiki girazi kanonzi pipette, kana kuti kanopinda pasiraidhi kana bvunzo.
• Bhandeji rinoiswa pamusoro penzvimbo iyi kumisa kubuda kweropa.

Muenzaniso weropa unoendeswa kubazi. Kune marudzi akati wandei enzira dzinoshandiswa kuona iwo ega amino acid mazinga muropa.

Munhu anenge aine bvunzo haafanire kudya maawa mana bvunzo isati yaitwa.

Panogona kuve nekurwadziwa kushoma kana kuruma kana tsono ikaiswa. Iwe unogona zvakare kunzwa kumwe kurovera panzvimbo iyi mushure mekudhonzwa kweropa. Tsvimbo tsono inogona kukonzera mucheche kana mwana kuchema.

Muedzo uyu unoitwa kuyera mwero wemaamino acids muropa.

Yakawedzera nhanho yeimwe amino asidhi chiratidzo chakasimba. Izvi zvinoratidza kuti pane dambudziko nekukwanisa kwemuviri kuputsa (kuisa muviri) iyo amino acid.

Iyo bvunzo inogona zvakare kushandiswa kutsvaga yakadzikira mazinga eamino acids muropa.

Kuwedzera kana kudzikira kwemazinga emaamino acids muropa anogona kuitika nefivha, kudya kwakakwana, uye mamwe marapirwo.

All zviyero zviri mu micromoles pa litre (µmol / L). Maitiro akajairwa anogona kusiyana pakati pemarabhoritari akasiyana. Taura nemupi wako wezvehutano nezve ako chaiwo mabvunzo.

Alanine:

• Vana: 200 kusvika ku450
• Vakuru: 230 kusvika 510

Alpha-aminoadipic asidhi:

• Vana: hazvionekwe
• Vakuru: haina kuwanikwa

Alpha-amino-N-butyric asidhi:

• Vana: 8 kusvika ku37
• Vakuru: 15 kusvika 41

Arginine:

• Vana: 44 kusvika 120
• Vakuru: 13 kusvika 64

Asparagine:

• Vana: 15 kusvika ku40
• Vakuru: 45 kusvika 130

Aspartic asidhi:

• Vana: 0 kusvika 26
• Vakuru: 0 kusvika 6

Beta-alanine:

• Vana: 0 kusvika 49
• Vakuru: 0 kusvika 29

Beta-amino-isobutyric asidhi:

• Vana: hazvionekwe
• Vakuru: haina kuwanikwa

Carnosine:

• Vana: hazvionekwe
• Vakuru: haina kuwanikwa

Citrulline:

• Vana: 16 kusvika 32
• Vakuru: 16 kusvika 55

Cystine:

• Vana: 19 kusvika ku47
• Vakuru: 30 kusvika 65

Glutamic acid:

• Vana: 32 kusvika ku140
• Vakuru: 18 kusvika 98

Glutamine:

• Vana: 420 kusvika 730
• Vakuru: 390 kusvika 650

Glycine:

• Vana: 110 kusvika 240
• Vakuru: 170 kusvika 330

Histidine:

• Vana: 68 kusvika 120
• Vakuru: 26 kusvika 120

Hydroxyproline:

• Vana: 0 kusvika ku5
• Vakuru: haina kuwanikwa

Isoleucine:

• Vana: 37 kusvika ku140
• Vakuru: 42 kusvika 100

Leucine:

• Vana: 70 kusvika 170
• Vakuru: 66 kusvika 170

Lysine:

• Vana: 120 kusvika 290
• Vakuru: 150 kusvika 220

Methionine:

• Vana: 13 kusvika ku30
• Vakuru: 16 kusvika 30

1-methylhistidine:

• Vana: hazvionekwe
• Vakuru: haina kuwanikwa

3-methylhistidine:

• Vana: 0 kusvika 52
• Vakuru: 0 kusvika 64

Ornithine:

• Vana: 44 kusvika 90
• Vakuru: 27 kusvika 80

Phenylalanine:

• Vana: 26 kusvika 86
• Vakuru: 41 kusvika 68

Phosphoserine:

• Vana: 0 kusvika 12
• Vakuru: 0 kusvika 12

Phosphoethanolamine:

• Vana: 0 kusvika 12
• Vakuru: 0 kusvika 55

Proline:

• Vana: 130 kusvika 290
• Vakuru: 110 kusvika 360

Serine:

• Vana: 93 kusvika ku150
• Vakuru: 56-140

Taurine:

• Vana: 11 kusvika 120
• Vakuru: 45 kusvika 130

Threonine:

• Vana: 67 kusvika ku150
• Vakuru: 92 kusvika 240

Tyrosine:

• Vana: 26 kusvika 110
• Vakuru: 45 kusvika 74

Valine:

• Vana: 160 kusvika ku350
• Vakuru: 150 kusvika 310

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Kuwedzera kweiyo yakazara huwandu hweamino acid muropa inogona kuve nekuda kwe:

• Eclampsia
• Inborn kukanganisa kwemetabolism
• Kusagadzikana kweFructose
• Ketoacidosis (kubva pashuga)
• Itsvo kutadza
• Reye chirwere
• Rabhoritari kukanganisa

Kuderera kweiyo yakazara huwandu hweamino acid muropa inogona kuve nekuda kwe:

• Adrenal cortical hyperfunction
• Kupindwa nechando
• Hartnup chirwere
• Inborn kukanganisa kwemetabolism
• Huntington chorea
• Kushaya zvokudya zvinovaka muviri
• Nephrotic chirwere
• Phlebotomus fever
• Rheumatoid arthritis
• Rabhoritari kukanganisa

Yakakwira kana yakaderera huwandu hwemunhu wega plasma amino acids inofanirwa kutariswa nerumwe ruzivo. Mhedzisiro isina kujairika inogona kunge iri yekudya, matambudziko enhaka, kana mhedzisiro yemushonga.

Kuongorora vacheche kumatanho akawedzera eamino acids kunogona kubatsira kuona matambudziko ane metabolism. Kurapa kwekutanga kwemamiriro aya kunogona kudzivirira matambudziko mune ramangwana.

Amino acids kuongororwa kweropa

• Amino acids

Dietzen DJ. Amino acids, peptides, uye mapuroteni. Mu: Rifai N, ed. Tietz Chinyorwa cheKiriniki Chemistry uye Molecular Diagnostics. 6th ed. St Louis, MO: Elsevier; 2018: chitsiko 28.

Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM. Kukanganisa mune metabolism yemamino acids. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chits. 103.

Riley RS, McPherson RA. Yekutanga kuongorora weti. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chitsiko 28.