Antinuclear antibody pani

Iyo antinuclear antibody pani ndeye kuongororwa kweropa kunotarisa maantinuclear antibodies (ANA).

ANA masoja ekudzivirira chirwere anogadzirwa nema immune system anosunga kumatumbu enyama. Iyo antiinuclear nyukiliya bvunzo inotsvaga maantibodies anosunga kune chikamu chechitokisi chinonzi nucleus. Kuongorora kwekuongorora kunoona kana masoja ekudzivirira akadai aripo. Muedzo zvakare unoyera chiyero, chinonzi titer, uye pateni, izvo zvinogona kubatsira.Kana iyo bvunzo iri yakanaka, pani yemuyedzo inogona kuitwa kuti itaridze yakatarwa antigen zvinangwa. Iyi ndiyo ANA antibody pani.

Ropa rinotorwa kubva mutsinga. Kazhinji kazhinji, tsinga iri mukati megokora kana kuseri kweruoko inoshandiswa. Nzvimbo iyi inoshambidzwa nemushonga unouraya utachiona (antiseptic). Anopa hutano anomonera bhandi rakasunga paruoko rwekumusoro kuisa kumanikidza kunzvimbo uye kuita kuti tsinga izate neropa.

Tevere, mupi anoisa zvinyoro nyoro mutsinga. Ropa rinoungana mumudziyo usingavharike mweya kana chubhu yakasungirirwa mutsono. Iyo yakasununguka bhandi inobviswa kubva paruoko rwako.

Ropa parangounganidzwa, tsono inobviswa, uye nzvimbo yekubaya inovharwa kumisa kubuda kweropa.

Mune vacheche kana vana vadiki, chishandiso chakapinza chinonzi lancet inogona kushandiswa kubaya ganda uye kuita kubuda ropa. Ropa rinoungana mutubhu tudiki girazi kanonzi pipette, kana panotsvedza kana bvunzo. Bhandeji rinogona kuiswa pamusoro penharaunda kana paine kubuda ropa.

Zvichienderana murabhoritari, bvunzo dzinogona kugadziriswa nenzira dzakasiyana. Imwe nzira inoda kuti nyanzvi iongorore muyero weropa pasi pe microscope uchishandisa ultraviolet mwenje. Imwe yacho inoshandisa chimbo chakazvimirira kunyora zvabuda.

Hapana gadziriro inokosha inodiwa. Nekudaro, mimwe mishonga, kusanganisira mapiritsi ekudzivirira kubereka, procainamide, uye thiazide diuretics, zvinokanganisa kunyatso kweiyi bvunzo. Ita shuwa kuti mupi wako anoziva nezve yese mishonga yaunotora.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanogona kungonzwa kubaya kana kuruma. Mushure meizvozvo, panogona kunge paine kurovera.

Iwe unogona kuda iyi bvunzo kana iwe uine zviratidzo zve autoimmune kusagadzikana, kunyanya systemic lupus erythematosus. Muedzo uyu unogona kuitwa kana uine zviratidzo zvisina tsananguro senge arthritis, mapundu, kana kurwadziwa pachipfuva.

Vamwe vanhu vakajairika vane yakaderera mwero we ANA. Nekudaro, kuvapo kwenzvimbo yakaderera yeAnA hakuwanzo kuita zvisina kujairika.

ANA inonzi "titer". Akaderera mazita ari mumatanho e1:40 kusvika 1:60. Chiyero cheAAA chakakosha chakanyanya kukosha kana iwe zvakare uine maantibhakitiriya anopesana nemhando mbiri-dzakarukwa dzeDNA.

Kuvapo kweAnA hakusimbisi kuongororwa kwe systemic lupus erythematosus (SLE). Zvisinei, kushayikwa kweAnA kunoita kuti kuongororwa kwacho kuve kushoma.

Kunyangwe ANA inowanzo kuverengerwa neSLE, yakanaka ANA bvunzo inogona zvakare kuve chiratidzo cheimwe autoimmune hosha.

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Kumwe kuyedza kunogona kumhanyisa paropa neyakajeka ANA bvunzo kuti uwane rumwe ruzivo.

Kuita kuti kuongororwa kweSLE, zvimwe zvemakiriniki uye ANA zvinofanirwa kunge zviripo. Uye zvakare, mamwe chaiwo maAAA antibodies anobatsira kusimbisa kuongororwa.

Kuvapo kweAnA muropa kunogona kunge kuri nekuda kweakawanda mamwe matambudziko kunze kweSLE. Izvi zvinosanganisira:

ZVIRWERE ZVIMWE

• Yakasanganiswa inobatanidza tishu chirwere
• Zvinodhaka-zvinokonzerwa lupus erythematosus
• Myositis (yekuzvimba tsandanyama chirwere)
• Rheumatoid arthritis
• Sjögren chirwere
• Systemic sclerosis (scleroderma)
• Utachiona chirwere
• Autoimmune hepatitis
• Lymphomas

ZVIRWERE

• EB hutachiona
• Hepatitis C
• HIV
• Parvovirus

Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe, uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kuwana ropa kubva kune vamwe vanhu kunogona kunetsa kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Hematoma (ropa rinoungana pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Wako mupi achashandisa mhedzisiro yeANA pani kuti ubatsire kuongorora. Vanenge vese vanhu vane SLE inoshanda vane ANA yakanaka. Zvisinei, ANA yakanaka pachayo haina kukwana kuti kuongororwa kweSLE kana chero chimwe chirwere chemuviri. Bvunzo dzeAAA dzinofanirwa kushandiswa pamwe neyako nhoroondo yezvekurapa, bvunzo dzepanyama uye kumwe kuedzwa kwerabhoritari.

ANA inogona kuve yakanaka mune hama dzevanhu vane SLE vasina SLE ivo pachavo.

Iko kune mukana wakaderera kwazvo wekuvandudza SLE pane imwe nguva gare gare muhupenyu kana iko chete kuwana kuri kwakaderera titer ye ANA.

ANA; ANA pani; ANA inojekesa pani; SLE - ANA; Yakarongeka lupus erythematosus - ANA

• Kuongorora ropa

Alberto von Mühlen C, Fritzler MJ, Chan EKL. Clinical uye rabhoritari kuongororwa kwe systemic rheumatic hosha. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chits. 52.

American College yeRheumatology webhusaiti. Antinuclear antibodies (ANA). www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA. Yakagadziridzwa Kurume 2017. Yakasvika muna Kubvumbi 04, 2019.

Reeves WH, Zhuang H, Han S. Autoantibodies mu systemic lupus erythematosus. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: chits. 139.