Glucose-6-phosphate dehydrogenase bvunzo

Glucose-6-phosphate dehydrogenase (G6PD) ipuroteni inobatsira masero matsvuku eropa kushanda nemazvo. Iyo G6PD bvunzo inotarisa huwandu (chiitiko) chechinhu ichi mumasero matsvuku eropa.

Muenzaniso weropa unodiwa.

Hapana gadziriro yakakosha inowanzo kuve inodikanwa.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Anopa hutano hwako anogona kukurudzira iyi bvunzo kana iwe uine zviratidzo zvekushomeka kweG6PD. Izvi zvinoreva kuti hauna zvakakwana G6PD chiitiko.

Zvishoma G6PD chiitiko chinotungamira mukuparadzwa kwemasero matsvuku eropa. Izvi zvinonzi hemolysis. Kana maitiro aya achinyatso kuitika, inonzi hemolytic episode.

Hemolytic episodes inogona kukonzerwa nehutachiona, zvimwe zvekudya (senge fava bhinzi), uye mimwe mishonga, inosanganisira:

• Zvinodhaka zvinoshandiswa kudzikisa kupisa muviri
• Nitrofurantoin
• Phenacetin
• Primaquine
• Sulfonamides
• Thiazide diuretics
• Tolbutamide
• Quinidine

Maitiro akajairika anosiyana uye zvinoenderana neirabhoritari yakashandiswa. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Zviitiko zvisina kujairika zvinoreva kuti une kushomeka kweG6PD. Izvi zvinogona kukonzera hemolytic anemia mune mamwe mamiriro.

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kuwana muyero weropa kubva kune vamwe vanhu kunogona kunetsa kupfuura kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
• Hematoma (kuwanda kweropa pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

RBC G6PD bvunzo; G6PD skrini

Chernecky CC, Berger BJ. Glucose-6-phosphate dehydrogenase (G6PD, G-6-PD), huwandu - ropa. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 594-595.

Gallagher PG. Hemolytic anemias: red sero membrane membrane uye metabolic kukanganisa. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits .152.