Alpha-1 antitrypsin ropa bvunzo

Alpha-1 antitrypsin (AAT) kuongororwa kwerabhoritari kuyera huwandu hweAAT muropa rako. Muedzo unoitwawo kuti utarise mafomu asina kujairika eAAT.

Muenzaniso weropa unodiwa.

Iko hakuna kugadzirira kwakakosha.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Iyi bvunzo inobatsira mukutsvaga iyo isingawanzo fomu yeemphysema muvanhu vakuru uye isingawanzo fomu yechiropa chirwere (cirrhosis) muvana nevakuru vanokonzerwa nekushomeka kweAAT. Kushomeka kweAAT kunoendeswa kuburikidza nemhuri. Mamiriro acho anoita kuti chiropa chigadzire kushoma kweAAT, puroteni inodzivirira mapapu nechiropa kubva mukukuvara.

Wese munhu ane maviri makopi ejeni anogadzira AAT. Vanhu vane maviri asina kujairika makopi ejeni vane chirwere chakanyanya uye kudzikira kweropa.

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nemupi wako wezvehutano nezve zvinorehwa nemimwe miedzo yako.

Iyo yepasi-kupfuura-yakajairwa nhanho yeAAT inogona kusangana ne:

• Kukuvadza kwenzira huru dzemumapapu (bronchiectasis)
• Kupenga kwechiropa (cirrhosis)
• Chirwere chisingaperi chinodzivirira pulmonary chirwere (COPD)
• Chiropa tumota
• Kupenya kweganda nemaziso nekuda kwekuvharirwa bile kuyerera (obstructive jaundice)
• Kuwedzera kweropa mumutsipa muhombe kunotungamira kuchiropa (portal hypertension)

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe, uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
• Hematoma (ropa rinoungana pasi peganda)
• Utachiona (njodzi diki chero nguva ganda parinovhunika)

A1AT bvunzo

Chernecky CC, Berger BJ. Arufa₁-antitrypsin - serum. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 121-122.

Winnie GB, Boas SR. a₁ - Antitrypsin kushomeka uye emphysema. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chap 421.