Myelodysplastic chirwere

Myelodysplastic syndrome iboka rezvinetso apo masero eropa anoburitswa mumongo wemapfupa asingakure kuita maseru ane hutano. Izvi zvinokusiya uine mashoma masero eropa ane hutano mumuviri wako. Masero eropa akura anogona kusashanda mushe.

Myelodysplastic syndrome (MDS) chimiro chekenza. Munenge chetatu chevanhu, MDS inogona kukura kuita acute myeloid leukemia.

Masero emashizha mumongo wemapfupa anoita mhando dzakasiyana dzemasero eropa. Ne MDS, iyo DNA iri mumasero maseru inozokuvara. Nekuti iyo DNA yakanganisika, masero emadzinde haakwanise kuburitsa masero eropa ane hutano.

Chikonzero chaicho che MDS hachizivikanwe. Kazhinji, hapana inozivikanwa chikonzero.

Njodzi zvinhu zve MDS zvinosanganisira:

• Zvimwe zvinokonzerwa nemagene
• Kuratidzirwa kune zvakatipoteredza kana maindasitiri makemikari, mafetiraiza, mishonga yekuuraya zvipuka, zvinonyungudika, kana simbi inorema
• Kusvuta

Kurapa kwegomarara kusati kwaitika kunowedzera njodzi kune MDS. Izvi zvinodaidzwa kuti zvechipiri kana zvine chekuita nekurapa MDS.

• Mamwe chemotherapy mishonga inowedzera mukana wekuvandudza MDS. Ichi chinhu chakanyanya njodzi.
• Radiation therapy, kana ikashandiswa nekemotherapy, inowedzera njodzi ye MDS zvakatonyanya.
• Vanhu vane stem cell transplants vanogona kukudziridza MDS nekuti ivo vanogashira yakakwira doses yekemotherapy.

MDS inowanzoitika kune vakuru vane makore makumi matanhatu ekuberekwa. Inowanzoitika kune varume.

Pakutanga MDS kazhinji haina zviratidzo. MDS inowanzo kuwanikwa panguva yekumwe kuongororwa kweropa.

Vanhu vane mashoma kwazvo kuverenga ropa vanowanzoona zviratidzo. Zviratidzo zvinoenderana nerudzi rweropa sero rakakanganiswa, uye zvinosanganisira:

• Kushaya simba kana kuneta nekuda kwekushaya ropa
• Kufema kwekufema
• Kupwanya kuri nyore uye kubuda ropa
• Diki dzvuku kana yepepuru inonongedza madota pasi peganda rinokonzerwa nekubuda ropa
• Kakawanda kutapukirwa nefivha

Vanhu vane MDS vane kushomeka kwemasero eropa. MDS inogona kudzikisa huwandu hweimwe kana dzakawanda dzeidzi:

• Masero matsvuku eropa
• Masero machena eropa
• Maplatelet

Maumbirwo emaseru aya anogona zvakare kuchinjwa. Anopa hutano hwako anozoita yakazara kuverenga ropa uye smear yeropa kuti uwane rudzii rweropa maseru akanganiswa.

Mimwe bvunzo inogona kuitwa ndeiyi:

• Bone marora chishuwo uye biopsy.
• Cytochemistry, kuyerera cytometry, immunocytochemistry, uye immunophenotyping bvunzo zvinoshandiswa kuzivisa uye kupatsanura mamwe marudzi e MDS.
• Cytogenetics uye fluorescent in situ kusanganiswa (FISH) zvinoshandiswa pakuongorora kwemajini. Kuongorora kweCytogenetic kunogona kuona kutama uye zvimwe zvisina kujairika. FISH inoshandiswa kuratidza shanduko chaiyo mukati memakromosomes. Kusiyana kwemajini kunogona kubatsira kuona mhinduro kurapa.

Mimwe yemiedzo iyi inobatsira mupi wako kuona kuti ndeapi rudzi rwe MDS yauinayo. Izvi zvinobatsira mupi wako kuronga kurapwa kwako.

Wako mupi anogona kutsanangura yako MDS seyakanyanya njodzi, yepakati-njodzi, kana yakaderera njodzi pahwaro hwe:

• Kuomarara kwekushomeka kwemasero eropa mumuviri wako
• Mhando dzekuchinja muDNA yako
• Huwandu hwevasina kuchena masero eropa mumapfupa ako

Sezvo paine njodzi yekuti MDS ikure kuva AML, kugara uchiteverwa nemupi wako kunogona kudikanwa.

Kurapa kwako kunoenderana nezvinhu zvinoverengeka:

• Kunyangwe iwe uri wepasi-njodzi kana wakanyanya njodzi
• Mhando yeMDS yauinayo
• Zera rako, hutano, uye mamwe mamiriro aungave uine, akadai seshuga kana chirwere chemwoyo

Chinangwa chekurapa MDS ndechekudzivirira matambudziko nekuda kwekushomeka kwemasero eropa, hutachiona uye kubuda ropa. Inogona kuve ne:

• Kuwedzerwa ropa
• Mishonga inosimudzira kugadzirwa kwemasero eropa
• Mishonga inodzvinyirira immune system
• Yakaderera-dose chemotherapy yekuvandudza masero eropa
• Stem sero kupinza

Wako mupi anogona kuyedza imwe kana dzakawanda kurapwa kuti aone kuti yako MDS inopindura sei.

Maonero anoenderana nemhando yako yeMDS uye kuomarara kwezviratidzo. Hutano hwako hwese zvakare hunogona kukanganisa mikana yako yekudzoka. Vanhu vazhinji vane MDS yakagadzikana isingafambi ikava kenza kwemakore, kana zvakadaro.

Vamwe vanhu vane MDS vanogona kukura zvakanyanya myeloid leukemia (AML).

Matambudziko eMDC anosanganisira:

• Kubuda ropa
• Utachiona hwakadai semabayo, utumbo, hutachiona
• Acute myeloid leukemia

Bata mupi wako kana iwe:

• Inzwa kupera simba uye kuneta nguva zhinji
• Kupwanya kana kubuda ropa zviri nyore, kuve nekubuda ropa pamatadza kana kubuda ropa kazhinji mumhino
• Unocherechedza mavara matsvuku kana epepuru ekubuda ropa pasi peganda

Myeloid yakaipa; Chirwere cheMyelodysplastic; MDS; Preleukemia; Kupfungaira leukemia; Reflectory kupererwa neropa; Inopikisa cytopenia

• Bone marora kushuvira

Hasserjian RP, Musoro DR. Myelodysplastic syndromes. Mune: Jaffe ES, Arber DA, Campo E, Harris NL, Quintanilla-Martinez L, eds. Hematopathology. 2nd ed. Philadelphia PA: Elsevier; 2017: chitsamba 45.

National Cancer Institute webhusaiti. Myelodysplastic / myeloproliferative neoplasms kurapwa (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/myeloproliferative/hp/mds-mpd-treatment-pdq. Yakagadziridzwa Kukadzi 1, 2019. Yakasvika December 17, 2019.

Steensma DP, Dombo RM. Myelodysplastic syndromes. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 172.