Munyori: Gregory Harris
Zuva Rekusika: 10 Kubvumbi 2021
Gadziridza Zuva: 16 Chivabvu 2024
Anonim
L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?
Vhidhiyo: L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?

Zvemukati

5-HTP (5-hydroxytryptophan) kemikari ne-chigadzirwa cheprotein chivakwa L-tryptophan. Inogadzirwawo zvekutengesa kubva pambeu yemuti wemuAfrica unozivikanwa seGriffonia simplicifolia.

5-HTP inoshandiswa pakurara hope dzakadai sekushaya hope, kushushikana, kushushikana, uye zvimwe zvakawanda mamiriro, asi hapana humbowo hwakanaka hwesainzi hunotsigira hwakawanda hwekushandisa.

Natural Mishonga Inonzwisisika Dhatabhesi zvinowanisa kushanda kunoenderana neuchapupu hwesainzi zvinoenderana nezviyero zvinotevera: Zvinobudirira, Zvichida Zvinobudirira, Zvichida Zvinobudirira, Zvichida Hazvishande, Zvichida Hazvibatsiri, Hazvibatsiri, uye Huchakwana Huchapupu hweKutara.

Iko kushanda ratings kwe 5-HTP zvinotevera:

Zvichida inoshanda kune ...

  • Kushungurudzika. Kutora 5-HTP nemuromo zvinoita sekuvandudza zviratidzo zvekushungurudzika mune vamwe vanhu. Kumwe kutsvagurudza kwekiriniki kunoratidza kuti kutora 5-HTP nemuromo kunogona kubatsira sekumwe kunwa zvinodhaka zvinodhaka zvekuvandudza kushushikana kwezviratidzo. Muzvidzidzo zvakawanda, 150-800 mg zuva nezuva ye5-HTP yakatorwa. Mune zvimwe zviitiko, mizinga yepamusoro yakashandiswa.

Pamwe hazvibatsiri ...

  • Down chirwere. Imwe tsvagiridzo inoratidza kuti kupa 5-HTP kuvacheche vane Down syndrome kunogona kuvandudza mhasuru uye chiitiko. Kumwe kutsvagurudza kunoratidza kuti hazvigadzirise mhasuru kana kukura kana zvatorwa kubva paucheche kusvika pamakore matatu kusvika matatu ekuberekwa. Tsvagiridzo inoratidza zvakare kuti kutora 5-HTP pamwe neyakajairika mishonga yemishonga inovandudza budiriro, hunyanzvi hwemagariro, kana hunyanzvi hwemutauro.

Husingakwani humbowo hwekuyera kushanda kwe ...

  • Rudzi rwekushushikana kunoonekwa nemafungiro anowanzoitika uye maitiro ekudzokorora (obsessive-compulsive disorder kana OCD). Kutsvagurudza kwekutanga kunoratidza kuti kutora 5-HTP ne antidepressant drug fluoxetine (Prozac) kwemavhiki gumi nemaviri kunogona kugadzirisa zvimwe zviratidzo zveOCD.
  • Doro rinoshandisa kusagadzikana. Ongororo yekutanga inoratidza kuti kutora 5-HTP neD-phenylalanine uye L-glutamine kwemazuva makumi mana kunogona kudzora zviratidzo zvekusiya doro. Zvisinei, kutora 5-HTP ne carbidopa zuva nezuva kwegore rimwe chete kunoratidzika kunge kunobatsira vanhu kurega kunwa. Mhedzisiro ye5-HTP yega kudhakwa haina kujeka.
  • Alzheimer chirwere. Kutsvagurudza kwekutanga kunoratidza kuti kutora 5-HTP nemuromo hakubatsire zviratidzo zvechirwere cheAlzheimer.
  • Kufunganya. Uchapupu pamhedzisiro ye5-HTP yekushushikana haina kujeka. Kutsvagurudza kwekutanga kunoratidza kuti kutora 25-150 mg ye5-HTP nemuromo zuva nezuva pamwe necarbidopa inoita kunge inoderedza zviratidzo zvekushushikana muvanhu vane kusagadzikana kwekushushikana. Nekudaro, kumwe kutsvagurudza kwekutanga kunoratidza kuti kutora mwero yakakwira ye5-HTP, 225 mg zuva nezuva kana kupfuura, zvinoita kunge kunowedzera kushushikana. Zvakare, kutora 60 mg ye5-HTP zuva nezuva kuburikidza nemutsinga hakudzikise kushushikana kune vanhu vane dambudziko rekutya.
  • Kukuvara kwehuropi kunokanganisa kufamba kwemhasuru (cerebellar ataxia). Uchapupu hwekushandiswa kwe5-HTP yecerebellar ataxia haina kujeka. Hwekutanga humbowo hunoratidza kuti kutora 5 mg / kg ye5-HTP zuva nezuva kwemwedzi mina kunogona kudzora huta hwekusashanda zvakanaka. Nekudaro, kumwe kutsvagurudza kunoratidza kuti kutora 5-HTP zuva rega rega kwegore rimwe hakugadzirise zviratidzo zvecerebellar ataxia.
  • Fibromyalgia. Kutsvagurudza kwekutanga kunoratidza kuti kutora 100 mg ye5-HTP nemuromo katatu zuva nezuva kwemazuva makumi matatu nemakumi mapfumbamwe kunogona kugadzirisa marwadzo, unyoro, kurara, kushushikana, kuneta, uye kuomarara kwemangwanani mune vanhu vane fibromyalgia.
  • Zviratidzo zvekuguma kuenda kumwedzi. Kutsvagurudza kwekutanga kunoratidza kuti kutora 150 mg ye5-HTP zuva rega rega kwemavhiki mana hakudzikise kupisa kunopisa mumadzimai ekumapopopaopausal.
  • Migraine. Uchapupu hwemhedzisiro ye5-HTP yekudzivirira kana kurapwa kwemigraines muvanhu vakuru haina kujeka. Zvimwe zvidzidzo zvinoratidza kuti kutora 5-HTP zuva rega rega hakudzikise migraines, nepo zvimwe zvidzidzo zvichiratidza kuti zvinogona kubatsira semushonga wemishonga. 5-HTP inoita kunge isingaderedze migraines muvana.
  • Kufutisa. Kutsvagurudza kwekutanga kunoratidza kuti kutora 5-HTP kunogona kubatsira kudzikisira kudya, caloric kudya, uye uremu muvanhu vakafutisa. Kumwe kutsvagurudza kunoratidza kuti kushandisa chaiyo yekumwaira muromo ine 5-HTP uye zvimwe zvinotsvairwa (5-HTP-Nat Exts, Medestea Biotech Sp, Torino, Italy) kwemavhiki mana kunowedzera kurasikirwa nekurema kweinenge 41% muvakadzi vane huremu hwemashure ekumiraopaopausal.
  • Kurega kubva kuheroin, morphine, uye mamwe maopioid zvinodhaka. Tsvagurudzo yekutanga inoratidza kuti kutora 200 mg ye5-HTP zuva nezuva kwemazuva matanhatu pamwe ne tyrosine, phosphatidylcholine, uye L-glutamine, kunogona kudzikisira kushaya hope uye kubvisa zviratidzo mukuwanazve heroin vakapindwa muropa.
  • Parkinson chirwere. Kutsvagurudza kwekutanga kunoratidza kuti kutora 100-150 mg ye5-HTP nemuromo zuva nezuva nemishonga yakajairika zvinoita kunge kunoderedza kuzunza, asi mabhenefiti aya anoenderera chete kusvika kumwedzi mishanu. Kumwe kutsvagurudza kwekutanga kunoratidza kuti kutora 50 mg ye5-HTP zuva nezuva kunogona kudzora zviratidzo zvekufamba kwekufamba kubva kune levodopa yezvinodhaka, pamwe nezviratidzo zvekuora mwoyo, muvanhu vane chirwere cheParkinson. Asi kutora muhombe madhayeti e5-HTP, 275-1500 mg zuva nezuva, pamwe necarbidopa zvinogona kuwedzera zvimwe zviratidzo.
  • Kunetseka musoro. Kutsvagurudza kwekutanga kunoratidza kuti kutora 100 mg ye5-HTP katatu zuva nezuva kwemavhiki masere hakudzikise marwadzo kana kureba kwekutambudzika kwemusoro.
  • Kucherekedza kusakwana-kusagadzikana kwehutano (ADHD).
  • Kusarara.
  • Premenstrual dysphoric disorder (PMDD).
  • Premenstrual syndrome (PMS).
  • Ramsey-Hunt chirwere.
  • Mamwe mamiriro.
Humwe humbowo hunodiwa kuyera kushanda kwe5-HTP kune izvi zvinoshandiswa.

5-HTP inoshanda muuropi uye yepakati tsinga system nekuwedzera kugadzirwa kwemakemikari serotonin. Serotonin inogona kukanganisa kurara, kudya, tembiricha, kuita zvepabonde, uye kurwadziwa kwekunzwa. Sezvo 5-HTP ichiwedzera iyo synthesis yeserotonin, inoshandiswa pazvirwere zvinoverengeka uko serotonin inofungidzirwa kuti inoita basa rakakosha kusanganisira kushushikana, kushaya hope, kufutisa, uye zvimwe zvakawanda mamiriro.

Kana ikatorwa nemuromo: 5-HTP ndiye ZVINOKOSHA KUNENGE kana uchitora nemuromo zvakakodzera. Yakave yakashandiswa zvakachengetedzeka mumadhosi kusvika ku400 mg zuva nezuva kusvika pagore rimwe chete. Asi vamwe vanhu vakatora 5-HTP vakagadzira mamiriro anonzi eosinophilia-myalgia syndrome (EMS). EMS mamiriro akakomba anosanganisira kunyanyisa kwemhasuru nyoro (myalgia) uye kusagadzikana kweropa (eosinophilia). Vamwe vanhu vanofunga kuti EMS inogona kukonzerwa nenjodzi inosanganisa kana kusvibisa mune zvimwe 5-HTP zvigadzirwa. Asi hapana humbowo hwakaringana hwesainzi hwekuziva kana EMS ichikonzerwa ne5-HTP, inosvibisa, kana chimwewo chinhu. Kusvikira zvimwe zvazivikanwa, 5-HTP inofanira kushandiswa zvine hungwaru.

Mimwe mhedzisiro yemhedzisiro ye5-HTP inosanganisira kurwadza kwemoyo, kurwadziwa mudumbu, kuda kurutsa, kurutsa, manyoka, kurara, matambudziko epabonde, uye mhasuru matambudziko.

5-HTP iri ZVINOGONESESA KUTI ASINA Kachengeteka painotorwa nemuromo muhombe madhizaini. Maitiro kubva ku6-10 gramu zuva rega rega ave akabatanidzwa kumatambudziko akakomba emudumbu uye mhasuru spasms.

Special matanho & yambiro:

Kubata uye kuyamwisa: Iko hakuna kukwana kwakaringana ruzivo rwekuziva kana 5-HTP yakachengeteka kushandisa kana uine pamuviri kana kuyamwisa. Gara padivi rakachengeteka uye dzivisa kushandisa.

Vana: 5-HTP ndiye ZVINOKOSHA KUNENGE painotorwa nemuromo zvakakodzera. Maitiro anosvika mashanu mg / kg zuva nezuva ave achishandiswa zvakachengeteka kweanosvika makore matatu muvacheche uye vana vanosvika gumi nemaviri-makore. Sezvo nevanhu vakuru, pane zvakare kunetsekana nezve mukana weeosinophilia-myalgia syndrome (EMS) muvana, chakakomba mamiriro chinosanganisira zvakanyanya mhasuru nyoro (myalgia) uye kusagadzikana kweropa (eosinophilia).

Kuvhiya: 5-HTP inogona kukanganisa kemikari yeuropi inonzi serotonin. Mimwe mishonga inoshandiswa panguva yekuvhiya inogona kukanganisa serotonin. Kutora 5-HTP usati wavhiyiwa kunogona kukonzera serotonin yakawandisa muuropi uye kunogona kukonzera mhedzisiro yakakomba kusanganisira matambudziko emoyo, kubvunda, uye kushushikana. Udza varwere kuti varege kutora 5-HTP kweinenge vhiki mbiri vasati vavhiyiwa.

Zvikuru
Usatore musanganiswa uyu.
Mishonga yekushungurudzika (MAOIs)
5-HTP inowedzera kemikari muuropi inonzi serotonin. Mimwe mishonga inoshandiswa kuora mwoyo inowedzerawo serotonin. Kutora 5-HTP nemishonga iyi inoshandiswa kushushikana kunogona kuwedzera serotonin zvakanyanya. Izvi zvinogona kukonzera zvakakomba mhedzisiro inosanganisira zvakanyanya kutemwa nemusoro, matambudziko emoyo, kubvunda, kuvhiringidzika, uye kusagadzikana.

Mimwe yemishonga iyi inoshandiswa kushushikana inosanganisira phenelzine (Nardil), tranylcypromine (Parnate), uye mimwe.
Pakati nepakati
Ive nekuchenjera nekubatanidzwa uku.
Carbidopa (Lodosyn)
5-HTP inogona kukanganisa huropi. Carbidopa (Lodosyn) inogona kukanganisa huropi. Kutora 5-HTP pamwe necarbidopa kunogona kuwedzera njodzi yemhedzisiro inokanganisa kusanganisira kutaura nekukurumidza, kushushikana, hasha, nevamwe.
Sedative mishonga (CNS inodzvinyirira)
5-HTP inogona kukonzera kurara uye kukotsira. Mishonga inokonzeresa kurara inonzi inonzi sedatives. Kutora 5-HTP pamwe chete nemishonga yekunyaradza kunogona kukonzera kurara zvakanyanya.

Mimwe mishonga yekunyaradza inosanganisira clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), nevamwe.
Serotonergic zvinodhaka
5-HTP inogona kuwedzera kemikari muuropi inonzi serotonin. Mimwe mishonga inowedzerawo serotonin. Kutora 5-HTP pamwe chete nemishonga iyi kunogona kuwedzera serotonin zvakanyanya. Izvi zvinogona kukonzera zvakakomba mhedzisiro inosanganisira zvakanyanya kutemwa nemusoro, matambudziko emoyo, kubvunda, kuvhiringidzika, uye kusagadzikana.

Mimwe yemishonga iyi inosanganisira fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Tofranil), sumatriptan (Imitrex), zolmitriptan (Zomig), rizatriptan methadone (Dolophine), tramadol (Ultram), nevamwe vazhinji.
Mishonga uye zvinowedzera zvine sedative zvivakwa
5-HTP inogona kukonzera kurara kana kukotsira. Kuishandisa pamwe nemamwe maruva uye zvinowedzera zvine maitiro akafanana zvinogona kukonzera kurara zvakanyanya. Mimwe yemishonga iyi uye zvinowedzera zvinosanganisira calamus, California poppy, catnip, hop, Jamaican dogwood, kava, St. John's wort, skullcap, valerian, yerba mansa, nezvimwe.
Mishonga uye zvinowedzera ne serotonergic zvivakwa
5-HTP inowedzera huropi kemikari inonzi serotonin. Kutora 5-HTP pamwe nemamwe maruva uye zvinowedzera izvo zvinowedzera serotonin zvinogona kutungamira kune yakawandisa serotonin uye zvinokonzeresa mhedzisiro kusanganisira matambudziko emoyo, kubvunda uye kushushikana. Mimwe miriwo uye zvinowedzera zvinowedzera serotonin mazinga anosanganisira Hawaiian baby woodrose, L-tryptophan, S-adenosylmethionine (SAMe), neSt.
Iko hakuna kuzivikanwa kudyidzana nezvikafu.
Iyi inotevera doses yakadzidzwa mukutsvaga kwesainzi: VAKURU

Nemuromo:
  • Zvekushungurudzika: Kazhinji, 150-800 mg zuva nezuva inotorwa kwemasvondo maviri ne6. Aya madosi dzimwe nguva anopatsanurwa kumusoro uye anotarisirwa se50 mg kusvika 100 mg katatu pazuva. Dzimwe nguva muyero unotanga wakadzika uye zvishoma nezvishoma unowedzera mavhiki maviri kusvika maviri kusvika padanho rekuvavarira rasvika. Zvishoma kazhinji, mizinga yepamusoro inoshandiswa. Mune kumwe kuongorora, muyero unowedzerwa zvishoma nezvishoma kusvika pamagiramu matatu pazuva.
2-Amino-3- (5-Hydroxy-1H-Indol-3-yl) Propanoic Acid, 5 Hydroxy-Tryptophan, 5 Hydroxy-Tryptophane, 5-Hydroxytryptophan, 5-Hydroxytryptophane, 5-Hydroxy L-Tryptophan, 5-Hydroxy L-Tryptophane, 5-Hydroxy Tryptophan, 5-L-Hydroxytryptophan, L-5 HTP, L-5-Hydroxytryptophan, L-5-Hydroxytryptophane, Oxitriptan.

Kuti udzidze zvakawanda nezvekuti chinyorwa ichi chakanyorwa sei, ndapota ona iyo Natural Mishonga Inonzwisisika Dhatabhesi nzira.


  1. Meloni M, Puligheddu M, Sanna F, uye al. Kubudirira uye kuchengetedzeka kwe5-Hydroxytryptophan pane levodopa-inosimudzira mota matambudziko muParkinson's chirwere: Yekutanga kutsvaga. J Neurol Sci. 2020; 415: 116869. Wona zvisingabvumirwe.
  2. Yousefzadeh F, Sahebolzamani E, Sadri A, et al. 5-Hydroxytryptophan seAdjuvant Therap pakurapa kwepakati nepakati kune zvakanyanya obsessive-inomanikidza kusagadzikana Int Kliniki Psychopharmacol. 2020; 35: 254-262. Wona zvisingabvumirwe.
  3. Javelle F, Lampit A, Bloch W, Häussermann P, Johnson SL, Zimmer P. Mhedzisiro ye5-hydroxytryptophan pamhando dzakasiyana dzekuora mwoyo: ongororo yakarongeka uye meta-ongororo. Nutriti Rev 2020; 78: 77-88. Wona zvisingabvumirwe.
  4. Meloni M, Puligheddu M, Carta M, Cannas A, Figorilli M, Defazio G. Kubudirira uye kuchengeteka kwe5-hydroxytryptophan pamusoro pekuora mwoyo uye kusava nehanya muchirwere chePasinson: kutanga kwekutsvaga. Eur J Neurol 2020; 27: 779-786. Wona zvisingabvumirwe.
  5. Israelyan N, Del Kore A, Li Z, et al. Mhedzisiro yeSerotonin uye Inononoka-Kuburitswa 5-Hydroxytryptophan paGastrointestinal Motility mune Mouse Model yekuora mwoyo. Gastroenterology. 2019; 157: 507-521.e4. Wona zvisingabvumirwe.
  6. Michelson D, Peji SW, Casey R, et al. Eosinophilia-myaligia syndrome inosangana nedambudziko rinosangana nekuratidzwa kune l-5-hydroxytryptophan. J Rheumatol 1994; 21: 2261-5. Wona zvisingabvumirwe.
  7. Lemaire PA, Adosraku RK. Iyo HPLC nzira yeiyo yakananga kuyedzwa kweserotonin preursor, 5-hydroxytrophan, mumbeu yeGriffonia simplicifolia. Phytochem Anal 2002; 13: 333-7 Tarisa zvinyorwa.
  8. Rondanelli M, Opizzi A, Faliva M, Bucci M, Perna S. Hukama pakati pekudyiwa kwe5-hydroxytryptophan kubva kuchikafu chakabatanidzwa, kuburikidza neGriffonia simplicifolia yakaburitswa, uye mhedzisiro yekuguta mune vakadzi vane huremu hwehuremu mushure mekutaurwa kwemuromo. Idya Kurema Kushushikana 2012; 17: e22-8. Wona zvisingabvumirwe.
  9. Pardo JV. Mania inotevera kuwedzerwa kwehydroxytryptophan kune monoamine oxidase inhibitor. Gen Hosp Psychiatry 2012; 34: 102.e13-4.
  10. Chen D, Liu Y, He W, Wang H, Wang Z. Neurotransmitter-preursor-yekuwedzera kupindira kwevakabvisa heroin vakapindwa muropa. J Huazhong Univ Sci Technolog Med Sci 2012; 32: 422-7.
  11. Gendle MH, Mudiki EL, Romano AC. Mhedzisiro yemuromo 5-hydroxytryptophan pane yakagadziriswa kuronga basa: nzwisiso mukugona dopamine / serotonin kudyidzana mune forebrain. Hum Psychopharmacol 2013; 28: 270-3.
  12. U.S. Food and Drug Administration Pharmacy Compounding Advisory Committee musangano June 17-18, 2015. Inowanikwa pa: www.fda.gov/downloads/advisorycommittee/committeemeetingmaterials/drugs/pharmacycompoundingadvisorycommittee/ucm455276.pdf (yakasvika musi wa8 / 21/15).
  13. US Chikafu uye Dhivhosi Kutonga. Nherera zvinodhaka zvinodhaka uye mvumo. Inowanikwa pa: www.accessdata.fda.gov/script/opdlisting/oopd/index.cfm (yakawanikwa musi wa8 / 20/2015).
  14. Das YT, Bagchi M, Bagchi D, Preuss HG. Kuchengetedzwa kwe5-hydroxy-L-tryptophan. Toxicol Lett 2004; 150: 111-22. Wona zvisingabvumirwe.
  15. Weise P, Koch R, Shaw KN, Rosenfeld MJ. Iko kushandiswa kwe5-HTP pakurapa Down's syndrome. Pediatrics 1974; 54165-8. Wona zvisingabvumirwe.
  16. Bazelon M, Paine RS, Cowie VA, et al. Kudzoreredzwa kwe hypotonia muvacheche vane Down's syndrome nekutungamira kwe5-hydroxytryptophan. Lancet 1967; 1: 1130-3. Wona zvisingabvumirwe.
  17. Sano I. Therapy yekuora mwoyo neL-5-hydroxytryptophan (L-5-HTP). Psychiatria et Neurologia Japonicas 1972; 74: 584.
  18. Klein P, Lees A, uye Stern G. Mhedzisiro yezvisingaperi 5-hydroxytryptophan mu parkinsonia kusagadzikana kwekufamba uye kuenzanisa uye mune kumwe kusagadzikana kwetsinga. Adv Neurol 1986; 45: 603-604.
  19. VanPraag, H. M. naKorf, J. 5-Hydroxytryptophan seanodzvinyirira. Kukosha kwekufungidzira kweiyo bvunzo yeprotenecid Psychopharmacol.Bull. 1972; 8: 34-35.
  20. Sicuteri F. 5-hydroxytryptophan muprophylaxis yemigraine. Pharmacological Research Kutaurirana 1972; 4: 213-218.
  21. Rosano Burgio, F., Borgatti, R., Scarabello, E., naLanzi, G. Kutemwa nemusoro muvana nevechiri kuyaruka. Proceedings of the First International Symposium on Headache in Children and Adolecents. 1989; 339-47.
  22. Mathew NT. 5-hydroxytryptophan muprophylaxis yemigraine: kudzidza kwakapofomara. Kutemwa nemusoro 1978; 18: 111.
  23. De Benedittis G, Massei R. 5-HT vanofanotungamira mune migraine prophylaxis: yakapofumadza-yakapofumara-pamusoro pekudzidza neL-5-hydroxytryptophan. Kliniki J Pain 1986; 2: 123-129.
  24. Wyatt, R. J., Vaughan, T., Kaplan, J., Galanter, M., uye Green, R. 5-Hydroxytryptophan uye chisingaperi schizophrenia. Mune: Barchas J uye Usdin E. Serotonin uye Maitiro. New York: Acedemic Press; 1973.
  25. Brodie HKH, Sack R, uye Siever L. Clinical zvidzidzo zveL-5-hydroxytryptophan mukuora mwoyo. Mune: Barchas J uye Usdin E. Serotonin uye hunhu. New York: Dzidzo Press; 1973.
  26. Auffret, M., Comte, H., uye Bene, J. Eosinophilia-myalgia syndrome inokonzerwa neL-5 hydroxytryptophane: anenge matatu kesi. Fund Clin Pharmacol 2013; Suppl 1: poster P2-204.
  27. Cangiano C, Laviano A, Del Ben M, et al. Mhedzisiro yemuromo 5-hydroxy-tryptophan pane simba rekudya uye macronutrient kusarudzwa mune vasiri-insulin vanovimba neshuga varwere. Int J Obes Relat Metab Disord 1998; 22: 648-54. Wona zvisingabvumirwe.
  28. Ju, C.Y. uye Tsai, C. T. Serotonergic nzira dzakabatanidzwa mukudzvinyirirwa kwekudyisa ne5-HTP mumakonzo. Chin J Physiol 1995; 38: 235-240. Wona zvisingabvumirwe.
  29. Pranzatelli, M. R., Tate, E., Galvan, I., na Wheeler, A. Muedzo unodzorwa we5-hydroxy-L-tryptophan ye ataxia mune inofambira mberi myoclonus pfari. Kliniki Neurol. 1996; 98: 161-164. Wona zvisingabvumirwe.
  30. Frith, C. D., Johnston, E. C., Joseph, M.H, Powell, R. J., uye Watts, R. W. Kaviri-bofu kiriniki kutongwa kwe5-hydroxytryptophan mune kesi yeLesch- Nyhan syndrome. J Neurol Neurosurg. Psychiatry 1976; 39: 656-662. Wona zvisingabvumirwe.
  31. Bastard, J., Truelle, J. L., naEmile, J. [Kubudirira kwe5 hydroxy-tryptophan muchirwere chePasinson]. Nouv Presse Med 9-11-1976; 5: 1836-1837. Wona zvisingabvumirwe.
  32. Trouillas P, Serratrice G, Laplane D, et al. Levorotatory fomu ye5-hydroxytryptophan muFriedreich's ataxia. Mhedzisiro yeakaviri-bofu drug-placebo mushandirapamwe kudzidza. Arch Neurol 1995; 52: 456-60. Wona zvisingabvumirwe.
  33. Wessel K, Hermsdörfer J, Deger K, et al. Kaviri-bofu crossover yekudzidza neyevorotatory fomu yehydroxytryptophan mune varwere vane degenerative cerebellar hosha. Arch Neurol 1995; 52: 451-5. Wona zvisingabvumirwe.
  34. Alino, J. J., Gutierrez, J. L., naIglesias, M. L. 5-Hydroxytryptophan (5-HTP) uye MAOI (nialamide) mukurapa kuora mwoyo. Yechipiri-bofu inodzorwa kudzidza. Int Pharmacopsychiatry 1976; 11: 8-15. Wona zvisingabvumirwe.
  35. Pranzatelli, M. R., Tate, E., Huang, Y., Haas, R. H., Bodensteiner, J., Ashwal, S., naFranz, D. Neuropharmacology yekufambira mberi kwemyoclonus pfari: kupindura 5- hydroxy-L-tryptophan. Kuora mwoyo 1995; 36: 783-791. Wona zvisingabvumirwe.
  36. Thomson, J., Rankin, H., Ashcroft, GW, Yates, CM, McQueen, JK, naCummings, SW Kurapa kwekushungurudzika mukuita kwakawanda: kuenzanisa kweL- tryptophan, amitriptyline, uye mubatanidzwa weL-tryptophan uye amitriptyline ine placebo. Psychol Med 1982; 12: 741-751. Wona zvisingabvumirwe.
  37. Trouillas, P., Garde, A., Robert, JM, Renaud, B., Adeleine, P., Bard, J., naBrudon, F. [Kudzoreredzwa kwechirwere checerebellar pasi pekutonga kwenguva refu kwe5-HTP kana mubatanidzwa we5-HTP uye benserazide. Makesi makumi maviri nematanhatu akaverengeka uye akarapwa achishandisa nzira dzemakomputa]. Rev Neurol. (Paris) 1982; 138: 415-435. Wona zvisingabvumirwe.
  38. Thal, L. J., Sharpless, N. S., Wolfson, L., naKatzman, R. Kurapa kwemyoclonus neL-5-hydroxytryptophan uye carbidopa: kiriniki, electrophysiological, uye biochemical kucherechedzwa. Ann Neurol 1980; 7: 570-576. Wona zvisingabvumirwe.
  39. van Hiele LJ. l-5-Hydroxytryptophan mukudzvinyirira: yekutanga kurapa kurapa mune zvepfungwa? Kurapa kwe99-kunze-varwere vane 'therapy-resistant' depressions. Neuropsychobiology 1980; 6: 230-40. Wona zvisingabvumirwe.
  40. Magnussen, ini.naNielsen-Kudsk, F. Bioavailability uye zvine hukama pharmacokinetics mune murume wemuromo anotungamirwa L-5-hydroxytryptophan mune yakadzikama mamiriro. Acta Pharmacol Toxicol. (Copenh) 1980; 46: 257-262. Wona zvisingabvumirwe.
  41. Trouillas, P., Garde, A., Robert, J. M., naAdeleine, P. [Kudzorerwa kwevanhu cerebellar ataxia pasi pekutonga kwenguva refu kwe5-hydroxytryptophan]. CR Kuona Acad Sci III 1-5-1981; 292: 119-122. Wona zvisingabvumirwe.
  42. Pueschel SM, Reed RB, Cronk CE, Goldstein BI. 5-hydroxytryptophan uye pyridoxine. Maitiro avo muvana vadiki vane Down's syndrome. Am J Dis Mwana 1980; 134: 838-44. Wona zvisingabvumirwe.
  43. Longo G, Rudoi I, Iannuccelli M, Strinati R, Panizon F. [Kurapa kwemusoro wakakosha mumazera ekukura pamwe neL-5-HTP (yambuka kaviri-bofu kudzidza maringe ne placebo)]. Pediatr Med Chir 1984; 6: 241-5. Wona zvisingabvumirwe.
  44. Bono, G., Micieli, G., Sances, G., Calvani, M., naNappi, G. L-5HTP kurapwa mumusoro wemusoro: kuyedza kuchipatara kuzivikanwa kwevanoteerera varwere. Cephalalgia 1984; 4: 159-165. Wona zvisingabvumirwe.
  45. Quadbeck, H., Lehmann, E., uye Tegeler, J. Kuenzanisa kweanodzvinyirira chiito che tryptophan, tryptophan / 5- hydroxytryptophan mubatanidzwa uye nomifensine. Neuropsychobiology 1984; 11: 111-115. Wona zvisingabvumirwe.
  46. van Praag, H. M. Mukutsvaga maitiro ekuita kweanodzvinyirira: 5-HTP / tyrosine musanganiswa mukuora mwoyo. Adv Biochem Psychopharmacol. 1984; 39: 301-314. Wona zvisingabvumirwe.
  47. Trouillas P. Kudzoreredza kwecerebellar syndrome ine-refu-nguva manejimendi ye5-HTP kana mubatanidzwa we5-HTP-benserazide: 21 kesi dzine huwandu hwezviratidzo zvakagadziriswa nekombuta. Ital J Neurol Sci 1984; 5: 253-266. Wona zvisingabvumirwe.
  48. van Praag, H. M. uye de Haan, S. Chemoprophylaxis yekushungurudzika. Kuedza kuenzanisa lithiamu ne5- hydroxytryptophan. Acta Psychiatr.Scand Suppl 1981; 290: 191-201. Wona zvisingabvumirwe.
  49. van Praag, H. uye de Hann, S. Kushungurudzika kunetseka uye 5-hydroxytryptophan prophylaxis. Psychiatry Res. 1980; 3: 75-83. Wona zvisingabvumirwe.
  50. Soulairac, A. [Hypnotic chiito che mecloqualone. Kufananidza nemhedzisiro ye placebo uye secobarbital]. Gadzirira Med 4-10-1971; 79: 817-818. Wona zvisingabvumirwe.
  51. Chase, T. N., Ng, L. K., uye Watanabe, A. M. Parkinson chirwere. Nadzurudzo 5-hydroxytryptophan. Neurology 1972; 22: 479-484. Wona zvisingabvumirwe.
  52. Wyatt, R. J., Vaughan, T., Galanter, M., Kaplan, J., uye Green, R. Maitiro ekuchinja kwevasingaperi schizophrenic varwere vakapihwa L-5- hydroxytryptophan. Sayenzi 9-22-1972; 177: 1124-1126. Wona zvisingabvumirwe.
  53. van Praag HM, Korf J, Dols LC, Schut T. Chidzidzo chekutyaira chekufungidzira kukosha kweiyo probenecid bvunzo mukushandisa kwe5-hydroxytryptophan seanodzvinyirira. Psychopharmacologia 1972; 25: 14-21. Wona zvisingabvumirwe.
  54. Zarcone, V., Kales, A., Scharf, M., Tan, T. L., Simmons, J. Q., uye Dement, W. C. Kudzokororwa kwemuromo kwe5-hydroxytryptophan. Maitiro ekuzvibata uye ekurara maitiro mune maviri schizophrenic vana. Arch Gen Psychiatry 1973; 28: 843-846. Wona zvisingabvumirwe.
  55. Chadwick, D., Hallett, M., Harris, R., Jenner, P., Reynolds, EH, uye Marsden, CD Clinical, biochemical, uye mamiriro ehupenyu anosiyanisa myoclonus inopindura 5-hydroxytryptophan, tryptophan ine monoamine oxidase inhibitor, uye clonazepam. Ubongo 1977; 100: 455-487. Wona zvisingabvumirwe.
  56. Van Woert, M.H, Rosenbaum, D., Howieson, J., uye Bowers, M. B., Jr. Kurapa kwenguva refu kwemyoclonus uye zvimwe zvinetswa neurologic neL-5- hydroxytryptophan uye carbidopa. N Engl J Med 1-13-1977; 296: 70-75. Wona zvisingabvumirwe.
  57. Nolen WA, van de Putte JJ, Dijken WA, Kamp JS. L-5HTP mune kushushikana kusagadzikana nekutora zvakare inhibitors. Chidzidzo chakavhurika chekuenzanisa ne tranylcypromine. Br J Psychiatry 1985; 147: 16-22. Wona zvisingabvumirwe.
  58. De Benedittis G, Massei R. Serotonin vapamberi mune chisingaperi chepfungwa musoro. Kaviri-bofu kuyambuka-pamusoro pekudzidza neL-5-hydroxytryptophan vs. placebo. J Neurosurg Sci 1985; 29: 239-48. Wona zvisingabvumirwe.
  59. Titus F, Dávalos A, Alom J, Codina A. 5-Hydroxytryptophan inopesana ne methysergide muprophylaxis yemigraine. Randomized kiriniki kutongwa. Eur Neurol 1986; 25: 327-9. Wona zvisingabvumirwe.
  60. Santucci M, Cortelli P, Rossi PG, Baruzzi A, Sacquegna T. L-5-hydroxytryptophan maringe ne placebo muhucheche migraine prophylaxis: mbiri-yakapofumadza crossover yekudzidza. Cephalalgia 1986; 6: 155-7. Wona zvisingabvumirwe.
  61. Irwin, M. R., Marder, S. R., Fuentenebro, F., uye Yuwiler, A. L-5-hydroxytryptophan inogadzirisa zviratidzo zvakanaka zvepfungwa zvinokonzerwa neD-amphetamine. Psychiatry Res. 1987; 22: 283-289. Wona zvisingabvumirwe.
  62. Angst J, Woggon B, Schoepf J. Kurapa kwekushungurudzika neL-5-hydroxytryptophan maringe nemipramine. Mhedzisiro yemaviri akavhurwa uye kamwe kaviri-bofu kudzidza. Arch Psychiatr Nervenkr 1977; 224: 175-86. Wona zvisingabvumirwe.
  63. Kahn RS, Westenberg HG, Verhoeven WM, uye al. Mhedzisiro yeserotonin inotungamira uye inotora inhibitor mumatambudziko ekuzvidya mwoyo; kuenzanisa kaviri-bofu kwe5-hydroxytryptophan, clomipramine uye placebo. Int Kliniki Psychopharmacol 1987; 21: 33-45. Wona zvisingabvumirwe.
  64. De Giorgis G, Miletto R, Iannuccelli M, Camuffo M, Scerni S. Musoro wemusoro mukubatana nematambudziko ekurara muvana: kuongororwa kwepfungwa uye kuongorora kiriniki - L-5-HTP maringe ne placebo. Zvinodhaka Exp Clin Res 1987; 13: 425-33. Wona zvisingabvumirwe.
  65. Zmilacher, K., Battegay, R., naGastpar, M. L-5-hydroxytryptophan voga uye pamwe chete neparipheral decarboxylase inhibitor mukurapa kwekuora mwoyo. Neuropsychobiology 1988; 20: 28-35. Wona zvisingabvumirwe.
  66. Nolen, W. A., van de Putte, J. J., Dijken, W. A., Kamp, J. S., Blansjaar, B. A., Kramer, H. J., naHaffmans, J. Kurapa nzira mukushushikana. II. MAO inhibitors mukuora mwoyo kunopesana necyclic antidepressants: maviri anodzorwa crossover zvidzidzo ne tranylcypromine maringe neL-5-hydroxytryptophan uye nomifensine. Acta Psychiatr.Scand 1988; 78: 676-683. Wona zvisingabvumirwe.
  67. Kaneko M, Kumashiro H, Takahashi Y, Hoshino Y. L-5HTP kurapwa uye serum 5-HT nhanho mushure meL-5-HTP kurodha pane vakaora mwoyo varwere. Neuropsychobiology 1979; 5: 232-40. Wona zvisingabvumirwe.
  68. Rousseau JJ. Mhedzisiro yeiyo levo-5-hydroxytryptophan-dihydroergocristine mubatanidzwa pane kushushikana uye neuropsychic performance: mbiri-bofu-inochengetedzwa placebo-inodzorwa kiriniki kutongwa kune vakwegura varwere. Kliniki Ther 1987; 9: 267-72. Wona zvisingabvumirwe.
  69. Anders, T. F., Cann, H. M., Ciaranello, R. D., Barchas, J. D., naBerger, P. A. Zvimwe zvinotariswa nezvekushandiswa kwe5-hydroxytryptophan mumwana ane chirwere cheLesch-Nyhan. Neuropadiatrie. 1978; 9: 157-166. Wona zvisingabvumirwe.
  70. Ceci F, Cangiano C, Cairella M, et al. Mhedzisiro yemuromo 5-hydroxytryptophan manejimendi pane yekudyisa hunhu mune vakafutisa vakadzi vakuru zvidzidzo. J Neural Transm 1989; 76: 109-17. Wona zvisingabvumirwe.
  71. Jangid P, Malik P, Singh P, Sharma M, Gulia AK. Kuenzanisa kudzidza kwekubudirira kwe l-5-hydroxytryptophan uye fluoxetine mune varwere vanouya neyekutanga kushushikana episode. Asia J Psychiatr 2013; 6: 29-34. Wona zvisingabvumirwe.
  72. Zarcone, V. P., Jr. naHoddes, E. Mhedzisiro ye5-hydroxytryptophan pakupatsanurwa kweREM kurara muzvidhakwa. Ndiri J Psychiatry 1975; 132: 74-76. Wona zvisingabvumirwe.
  73. Opladen, T., Hoffmann, G. F., naBlau, N. Kuongorora kwepasi rose kwevarwere vane tetrahydrobiopterin kushomeka kunouya ne hyperphenylalaninaemia. J Nhaka. Metab Dis 2012; 35: 963-973. Wona zvisingabvumirwe.
  74. Baraldi, S., Hepgul, N., Mondelli, V., uye Pariante, C. M. Syndromeomatic kurapwa kweiyo interferon-alpha-inokonzeresa kuora mwoyo muhepatitis C: yakarongeka ongororo. J Clin Psychopharmacol. 2012; 32: 531-543. Wona zvisingabvumirwe.
  75. Pan, L., McKain, BW, Madan-Khetarpal, S., Mcguire, M., Diler, RS, Perel, JM, Vockley, J., uye Brent, DA GTP-cyclohydrolase kushomeka kunopindura sapropterin uye 5-HTP yekuwedzera. : kuregererwa kwekurapa-kunokanganisa kushushikana uye maitiro ekuzviuraya. BMJ Nyaya. 2011; 2011 Wona zvisingabvumirwe.
  76. Friedman, J., Roze, E., Abdenur, JE, Chang, R., Gasperini, S., Saletti, V., Wali, GM, Eiroa, H., Neville, B., Felice, A., Parascandalo, R., Zafeiriou, DI, Arrabal-Fernandez, L., Dill, P., Eichler, FS, Echenne, B., Gutierrez-Solana, LG, Hoffmann, GF, Hyland, K., Kusmierska, K., Tijssen, MA, Lutz, T., Mazzuca, M., Penzien, J., Poll-Iyo BT, Sykut-Cegielska, J., Szymanska, K., Thony, B., uye Blau, N. Sepiapterin reductase kushomeka: kurapa mimhanzi yecerebral palsy. Ann Neurol. 2012; 71: 520-530. Wona zvisingabvumirwe.
  77. Jukic T, Rojc B, Boben-Bardutzky D, Hafner M, Ihan A. Kushandiswa kwechikafu chekuwedzera pamwe naD-phenylalanine, L-glutamine uye L-5-hydroxytriptophan mukuderedza zviratidzo zvekusiya doro. Coll Antropol 2011; 35: 1225-30. Wona zvisingabvumirwe.
  78. Sarris, J. Clinical kushushikana: humbowo-hwakavakirwa mukubatanidza unowedzerana mushonga wekurapa modhi. Imwe.Ther.Health Med. 2011; 17: 26-37. Wona zvisingabvumirwe.
  79. Dill, P., Wagner, M., Somerville, A., Thony, B., Blau, N., naWeber, P. Mwana neurology: paroxysmal kuomesa, kutarisa kumusoro, uye hypotonia: zviratidzo zve sepiapterin reductase kushomeka. Neurology 1-31-2012; 78: e29-e32. Wona zvisingabvumirwe.
  80. Horvath, GA, Selby, K., Poskitt, K., Hyland, K., Waters, PJ, Coulter-Mackie, M., uye Stockler-Ipsiroglu, SG Hemiplegic migraine, pfari, inofambira mberi spastic paraparesis, kusagadzikana kwepfungwa, uye coma muvanun'una vane yakaderera systemic serotonin. Cephalalgia 2011; 31: 1580-1586. Wona zvisingabvumirwe.
  81. Morrison, K. E. Yese-genome kurongedzera kunozivisa kurapwa: mushonga wakasarudzika unotora rimwe danho kumberi. Kliniki Chem 2011; 57: 1638-1640. Wona zvisingabvumirwe.
  82. Bainbridge, MN, Wiszniewski, W., Murdock, DR, Friedman, J., Gonzaga-Jauregui, C., Newsham, I., Reid, JG, Fink, JK, Morgan, MB, Gingras, MC, Muzny, DM, Hoang, LD, Yousaf, S., Lupski, JR, uye Gibbs, RA Yese-genome kuenzanisira kweakagadziriswa manejimendi manejimendi. Sci Dudziro.Med 6-15-2011; 3: 87re3. Wona zvisingabvumirwe.
  83. den Boer JA, Westenberg HG. Maitiro, neuroendocrine, uye biochemical mhedzisiro ye5-hydroxytryptophan manejimendi mukutya chirwere. Psychiatry Res 1990; 31: 267-78. Wona zvisingabvumirwe.
  84. Adamsen, D., Meili, D., Blau, N., Thony, B., uye Ramaekers, V. Autism inosangana neyepasi 5-hydroxyindolacetic acid mu CSF uye heterozygous SLC6A4 gene Gly56Ala pamwe ne5-HTTLPR L / L inosimudzira misiyano. . Mol.Geneti.Metab 2011; 102: 368-373. Wona zvisingabvumirwe.
  85. Muchinjikwa, D. R., Kellermann, G., McKenzie, L. B., Purvis, K. B., Hill, G. J., naHuisman, H. A yakarongedzwa yakatarwa amino acid kurapa nehunhu hwekuzvibata huri panjodzi vana vakagamuchirwa. Kuchengeta Kwevana Hutano Dev. 2011; 37: 671-678. Wona zvisingabvumirwe.
  86. Gendle, M.H naGolding, A. C. Oral manejimendi ye5-hydroxytryptophan (5-HTP) inokanganisa kutora sarudzo pasi pekusanzwisisika asi kwete pasi penjodzi: humbowo kubva kuIowa Kubheja Basa. Hum Psychopharmacol. 2010; 25: 491-499. Wona zvisingabvumirwe.
  87. Iovieno, N., Dalton, E. D., Fava, M., uye Mischoulon, D. Yechipiri-tier yakasikwa antidepressants: kuongorora uye kuongorora. J Inobata Kupesana. 2011; 130: 343-357. Wona zvisingabvumirwe.
  88. Leu-Semenescu, S., Arnulf, I., Decaix, C., Moussa, F., Clot, F., Boniol, C., Touitou, Y., Levy, R., Vidailhet, M., uye Roze, E. Kurara uye mutinhimira mhedzisiro yemageneti akakonzera kurasikirwa kweserotonin. Kurara 3-1-2010; 33: 307-314. Wona zvisingabvumirwe.
  89. Freedman RR. Kurapa kweanopaopausal kupisa kupenya ne5-hydroxytryptophan. Maturitas 2010; 65: 383-5. Wona zvisingabvumirwe.
  90. Mavhiki, B. S. Maumbirwo ezvekuwedzera zvekudya uye mishonga yemakwenzi yekuzorora uye yekufunganya chiito: Relarian. Med Sci Monit. 2009; 15: RA256-RA262. Wona zvisingabvumirwe.
  91. Rondanelli M, Klersy C, Iadarola P, uye al. Satiety uye amino-acid chimiro mune vakadzi vakafutisa mushure mekurapa nyowani vachishandisa chirimwa chechisikirwo chinobvisa zvinyorwa zvemhando yepamusoro. Int J Obes (Chiedza) 2009; 33: 1174-1182. Wona zvisingabvumirwe.
  92. Maissen CP, Ludin HP. [Kufananidza nemhedzisiro ye5-hydroxytryptophan uye propranolol munguva yekurapa kwemigraine]. Schweiz Med Wochenschr 1991; 121: 1585-90. Wona zvisingabvumirwe.
  93. Shell W, Bullias D, Charuvastra E, et al. Chiyero chisingachinjiki, chinodzorwa ne placebo cheamino acid kugadzirira panguva uye mhando yekurara. Am J Ther 2010; 17: 133-9. Wona zvisingabvumirwe.
  94. Trujillo-Martin, M. M., Serrano-Aguilar, P., Monton-Alvarez, F., naCarrillo-Fumero, R. Kubudirira uye kuchengetedzwa kwemishonga yekurapa ataxias: yekuongorora kwakarongeka. Mov Kusagadzikana. 6-15-2009; 24: 1111-1124. Wona zvisingabvumirwe.
  95. Rothman, R. B. Kurapa kwekuneta ne "mubatanidzwa" pharmacotherapy. Am J Ther 2010; 17: 596-603. Wona zvisingabvumirwe.
  96. Chae, HS, Kang, OH, Choi, JG, Oh, YC, Lee, YS, Jang, HJ, Kim, JH, Park, H., Jung, KY, Sohn, DH, uye Kwon, DY 5-hydroxytryptophan inoshanda pa iyo mitogen-activated protein kinase extracellular-chiratidzo chinodzorwa protein kinase nzira yekugadzirisa cyclooxygenase-2 uye inducible nitric oxide synthase expression muRAW 264.7 masero. Biol Pharm Bull 2009; 32: 553-557. Wona zvisingabvumirwe.
  97. Hendricks, E. J., Rothman, R. B., naGreenway, F. L. Mahunyanzvi vezvekurapa vanoshandisa zvinodhaka kurapa kufutisa. Kufutisa. (Sirivha.Spring) 2009; 17: 1730-1735. Wona zvisingabvumirwe.
  98. Longo, N. Kukanganiswa kwe biopterin metabolism. J Nhaka. Metab Dis 2009; 32: 333-342. Wona zvisingabvumirwe.
  99. Pons, R. Iyo phenotypic spectrum yezvirwere zvevana neurotransmitter hosha uye infile parkinsonism. J Nhaka. Metab Dis 2009; 32: 321-332. Wona zvisingabvumirwe.
  100. Schaefer, M., Winterer, J., Sarkar, R., Uebelhack, R., Franke, L., Heinz, A., naFriebe, A. Zviitiko zvitatu zve tryptophan add-on kana monotherapy ye hepatitis C uye IFNalpha -kusanganiswa kwemanzwiro. Psychosomatics 2008; 49: 442-446. Wona zvisingabvumirwe.
  101. Jacobsen, JP, Nielsen, EO, Hummel, R., Redrobe, JP, Mirza, N., uye Weikop, P. Insensitivity yeNMRI mbeva kusarudza serotonin reuptake inhibitors mumuswe wekumiswa bvunzo inogona kudzoserwa nekubatana pamwe ne5 -hydroxytryptophan. Psychopharmacology (Berl) 2008; 199: 137-150. Wona zvisingabvumirwe.
  102. Liu, K. M., Liu, T. T., Lee, N. C., Cheng, L.Y., Hsiao, K. J., naNui, D. M. Kwenguva refu kuteedzerwa kwevarwere veTaiwanese Chinese vanorapwa nekukurumidza kwe6-pyruvoyl-tetrahydropterin synthase kushomeka. Arch Neurol. 2008; 65: 387-392. Wona zvisingabvumirwe.
  103. Horvath, GA, Stockler-Ipsiroglu, SG, Salvarinova-Zivkovic, R., Lillquist, YP, Connolly, M., Hyland, K., Blau, N., Rupar, T., uye Mvura, PJ Autosomal yakawandisa GTP cyclohydrolase I kushomeka pasina hyperphenylalaninemia: humbowo hwe phenotypic kuenderera pakati pemafomu akakurisa uye akawandisa. Mol.Geneti.Metab 2008; 94: 127-131. Wona zvisingabvumirwe.
  104. Morrow, J. D., Vikraman, S., Imeri, L., uye Opp, M. R. Mhedzisiro yeserotonergic activation ne5-hydroxytryptophan pakurara uye tembiricha yemuviri weC57BL / 6J uye mbeva dze interleukin-6-dzakashomeka idosi uye nguva inoenderana. Kurara 1-1-2008; 31: 21-33. Wona zvisingabvumirwe.
  105. Meolie, AL, Rosen, C., Kristu, D., Kohrman, M., Gooneratne, N., Aguillard, RN, Fayle, R., Troell, R., Townsend, D., Claman, D., Hoban, T., naMahowald, M. Oral isinganyorerwe kurapwa kwehope: kuongororwa kwezvigadzirwa zvine humbowo hushoma. J Clin Kurara Med 4-15-2005; 1: 173-187. Wona zvisingabvumirwe.
  106. Cangiano C, Ceci F, Cairella M, et al. Mhedzisiro ye5-hydroxytryptophan pakudya maitiro uye kunamatira kune zvekudya zvirevo mune vakafutisa vakuru zvidzidzo. Adv Exp Med Biol. 1991; 294: 591-3. Wona zvisingabvumirwe.
  107. Petre-Quadens, O. naDe Lee, C. 5-Hydroxytryptophan uye vanorara muDown's syndrome. J Neurol Sci 1975; 26: 443-453. Wona zvisingabvumirwe.
  108. Lesch, K. P., Hoh, A., Disselkamp-Tietze, J., Wiesmann, M., Osterheider, M., uye Schulte, H. M. 5-Hydroxytryptamine1A kugashira kwekugamuchira mukutadza-kumanikidza kusagadzikana. Kufananidza kwevarwere uye kutonga. Arch Gen Psychiatry 1991; 48: 540-547. Wona zvisingabvumirwe.
  109. Halladay, AK, Wagner, GC, Sekowski, A., Rothman, RB, Baumann, MH, naFisher, H. Shanduko mukunwa doro, kutapudza, uye monoamine kufambisa mumakonzo anorapwa ne phentermine uye 5-hydroxy-L-tryptophan . Synapse 2006; 59: 277-289. Wona zvisingabvumirwe.
  110. Curcio, J. J., Kim, L. S., Wollner, D., uye Pockaj, B. A. Iko kugona kwe5-hydryoxytryptophan yekupisa kupisa kupisa: fungidziro. Imwe Med Rev 2005; 10: 216-221. Wona zvisingabvumirwe.
  111. Victor, S. naRyan, S. W. Zvinodhaka zvekudzivirira migraine kutemwa nemusoro muvana. Cochrane Dhatabhesi.Syst.Rev 2003; CD002761. Wona zvisingabvumirwe.
  112. George DT, Lindquist T, Rawlings RR, et al. Pharmacologic kuchengetedza kwekurega muvarwere vane chidhakwa: hapana kushanda kwe5-hydroxytryptophan kana levodopa. Clin Pharmacol Ther 1992; 52: 553-60. Wona zvisingabvumirwe.
  113. Shaw, K., Turner, J., naDel Mar, C. Tryptophan uye 5-hydroxytryptophan yekushungurudzika. Cochrane Dhatabhesi.Syst Rev 2002; CD003198. Wona zvisingabvumirwe.
  114. Ciaranello, R. D., Anders, T. F., Barchas, J. D., Berger, P. A., naCann, H. M. Iko kushandiswa kwe5-hydroxytryptophan mumwana ane Lesch-Nyhan syndrome. Mwana Psychiatry Hum Dev 1976; 7: 127-133. Wona zvisingabvumirwe.
  115. Anderson, L.T, Herrmann, L., naDancis, J. Mhedzisiro yeL-5-hydroxytryptophan pane-yega mutilatin muchirwere cheLesch-Nyhan: mushumo wakashata. Neuropadiatrie. 1976; 7: 439-442. Wona zvisingabvumirwe.
  116. Growdon, J. H., Muduku, R. R., uye Shahani, B. T. L-5-hydroxytryptophan mukurapa syndromes dzakasiyana dzakasiyana umo myoclonus inozivikanwa. Neurology 1976; 26: 1135-1140. Wona zvisingabvumirwe.
  117. Takahashi S, Kondo H, Kato N. Mhedzisiro ye-l-5-hydroxytryptophan pahuropi monoamine metabolism uye kuongororwa kweiyo kiriniki mhedzisiro mune vakaora mwoyo varwere. J Psychiatr Res 1975; 12: 177-87. Wona zvisingabvumirwe.
  118. Preshaw RM, Leavitt D, Hoag G. Chikafu chinowedzera 5-hydroxytryptophan uye weti 5-hydroxyindole acetic acid. CMAJ 2008; 178: 993. Wona zvisingabvumirwe.
  119. Byerley WF, Judd LL, Reimherr FW, Grosser BI. 5-Hydroxytryptophan: ongororo yeayo antidepressant inoshanda uye yakaipa migumisiro J Clin Psychopharmacol 1987; 7: 127-37 .. Wona zvisiri izvo.
  120. Shaw K, Turner J, Del Mar C. Tryptophan uye 5-hydroxytryptophan yekushungurudzika. Cochrane Dhatabhesi Syst Rev 2002;: CD003198. Wona zvisingabvumirwe.
  121. Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V. Kaviri-bofu kudzidza kwe5-hydroxytryptophan maringe ne placebo mukurapa kwepakutanga fibromyalgia syndrome. J Int Med Res 1990; 18: 201-9. Wona zvisingabvumirwe.
  122. Johnson KL, Klarskov K, Benson LM, et al. Kuvapo kwepamusoro X nemakemikari akafanana: iyo yakasviba yakasviba mune inoenderana 5-hydroxy-L-tryptophan inosangana ne eosinophilia-myalgia syndrome. J Rheumatol 1999; 26: 2714-7. Wona zvisingabvumirwe.
  123. Singhal AB, Caviness VS, Begleiter AF, et al. Cerebral vasoconstriction uye sitiroko mushure mekushandisa kweserotonergic zvinodhaka. Neurology 2002; 58: 130-3. Wona zvisingabvumirwe.
  124. U. S. Kudya neDrug Administration, Center yeKudya Kudzivirirwa uye Applied Nutrition, Hofisi yeZvekudya Zvigadzirwa, Kunyora, uye Kudya Kwekuwedzera. Ruzivo Runyorwa paL-Tryptophan uye 5-hydroxy-L-tryptophan, Kukadzi 2001.
  125. Nardini M, De Stefano R, Iannuccelli M, uye al. Kurapa kwekushungurudzika neL-5-hydroxytryptophan inosanganiswa neklorimipramine, yakapetwa-bofu kudzidza. Int J Kliniki Pharmacol Res 1983; 3: 239-50. Wona zvisingabvumirwe.
  126. Ribeiro CA. L-5-Hydroxytryptophan muprophylaxis yeasingaperi tension-mhando misoro: mbiri-bofu, yakasarudzika, placebo-inodzorwa kudzidza. Musoro 2000; 40: 451-6. Wona zvisingabvumirwe.
  127. Poldinger W, Calanchini B, Schwarz W. Maitiro anoshanda-akasarudzika ekuora mwoyo: kushomeka kweserotonin sechinangwa syndrome mukuenzanisa 5-hydroxytryptophan uye fluvoxamine. Psychopathology 1991; 24: 53-81. Wona zvisingabvumirwe.
  128. Sternberg EM, Van Woert MH, Mudiki SN, et al. Kubudirira kwe scleroderma-senge kurwara panguva yekurapa neL-5-hydroxytryptophan uye carbidopa. N Engl J Med 1980; 303: 782-7. Wona zvisingabvumirwe.
  129. US Chikafu uye Dhivhosi Kutonga. Tsvina yakasimbiswa mukudya kwekuwedzera 5-hydroxy-L-tryptophan. FDA Kutaura Pepa, Nyamavhuvhu 31, 1998; T98-48.
  130. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter inotungamira amino acids pakurapa kweakawanda-infarct dementia uye chirwere cheAlzheimer. J Amer Geriat Soc 1977; 25: 289-98. Wona zvisingabvumirwe.
  131. Trouillas P, Brudon F, Adeleine P.Kuvandudzwa kwecerebellar ataxia ine levorotatory fomu ye5-hydroxytryptophan: kudzidza kwakapofumadza-kupofumadza pamwe nekugadziriswa kwedata. Arch Neurol 1988; 45: 1217-22. Wona zvisingabvumirwe.
  132. Kahn RS, Westenberg HG. L-5-hydroxytryptophan mukurapa kusagadzikana kwekushushikana. J Inobata Kusawirirana 1985; 8: 197-200. Wona zvisingabvumirwe.
  133. Cangiano C, Ceci F, Cancino A, et al. Kudya maitiro uye kuomerera kune zvekudya zvirevo mune vakafutisa vakuru zvidzidzo zvinorapwa ne5-hydroxytryptophan. Am J Kliniki Nutriti 1992; 56: 863-7. Wona zvisingabvumirwe.
  134. Sarzi Puttini P, Caruso I. Primary fibromyalgia syndrome uye 5-hydroxy-L-tryptophan: 90-zuva rakavhurika kudzidza. J Int Med Res 1992; 20: 182-9. Wona zvisingabvumirwe.
  135. Nakajima T, Kudo Y, Kaneko Z.Kiriniki kuongororwa kwe5-hydroxy-L-tryptophan semushonga unodzvinyirira. Folia Psychiatr Neurol Jpn 1978; 32: 223-30. Wona zvisingabvumirwe.
  136. Michelson D, Peji SW, Casey R, et al. Eosinophilia-myalgia syndrome inosangana nedambudziko inosangana nekuratidzwa kune L-5-hydroxytryptophan. J Rheumatol 1994; 21: 2261-5. Wona zvisingabvumirwe.
  137. Shiri TC. 5-Hydroxytryptophan: Inoshanda-Inoshanda Serotonin Precursor. Imwe Med Rev 1998; 3: 271-80. Wona zvisingabvumirwe.
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