Tacrolimus

Zvemukati

• Usati watora tacrolimus,
• Tacrolimus inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, kana izvo zvataurwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukasira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

Tacrolimus inofanirwa kupihwa chete pasi pekutarisirwa nachiremba ane ruzivo rwekurapa vanhu vakaiswa nhengo uye mukumisikidza mishonga inoderedza mashandiro ezvirwere zvemuviri.

Tacrolimus inoderedza mashandiro e immune system yako. Izvi zvinogona kuwedzera njodzi yekuti iwe utore hutachiona hwakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: huro; kukosora; kupindwa nechando; kuneta kwakanyanya; flu-kunge zviratidzo; inodziya, tsvuku, kana inorwadza ganda; kana zvimwe zviratidzo zvehutachiona.

Kana immune system yako isiri kushanda zvakajairika, pangave nenjodzi huru yekuti uchava nekenza, kunyanya lymphoma (rudzi rwekenza inotanga mumasero edziviriro yezvirwere mumuviri). Kana iwe uchingotora tacrolimus kana imwe mishonga inoderedza mashandiro ezvirwere zvemuviri, uye nekukwirisa dosi yako yemishonga iyi, zvakanyanya njodzi iyi inogona kuwedzera. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinetseka. kuonda; kupindwa nechando; husiku hweziya; kuneta zvakanyanya kana kushaya simba; kukosora; kunetseka kufema; kurwadziwa muchipfuva; kana kurwadziwa, kuzvimba, kana kuzara mudumbu nzvimbo.

Zvidzidzo zvakaratidza kuti vakadzi vakagamuchira chiropa chekuisa uye vaitora tacrolimus yakawedzerwa-kuburitswa makapuru (Astagraf XL) vaive nenjodzi yekufa. Tacrolimus akawedzera-kuburitsa makapuleti (Astagraf XL) haatenderwe neFDA kudzivirira kurambwa (kurwisa kwechimwe chinhu chakasimwa nema immune system emunhu ari kutambira nhengo) yechiropa.

Taura nachiremba wako nezve njodzi dzekutora tacrolimus.

Tacrolimus (Astagraf XL, Envarsus XR, Prograf) inoshandiswa pamwe chete nemimwe mishonga yekudzivirira kurambwa (kurwisa kwechimwe chinhu chakasimwa ne immune system yemunhu anogamuchira iyo nhengo) muvanhu vakagamuchira kuisirwa itsvo. Tacrolimus (Prograf) inoshandiswa zvakare pamwe chete nemimwe mishonga yekudzivirira kurambwa muvanhu vakagamuchira chiropa kana moyo wekuisira. Tacrolimus iri mukirasi yemishonga inonzi immunosupressants. Inoshanda nekuderedza mashandiro edziviriro yezvirwere kuzvidzivirira kubva pakurwisa nhengo yakaiswa.

Tacrolimus inouya secapsule, granules yekumiswa pamuromo (kuti isanganiswe nemvura), yakawedzerwa-kuburitsa (refu kuita) kapsule, uye piritsi rakaregedzwa-rekutora kutora nemuromo. Iwo ekukurumidza-kuburitswa macapsule (Prograf) uye kumiswa kwemuromo (Prograf) anowanzo kutorwa kaviri pazuva (maawa gumi nemaviri akaparadzana). Iwe unogona kutora izvozvi-kuburitsa makaputa uye kumiswa pamuromo pamwe kana kana pasina chikafu, asi ive shuwa kuitora nenzira imwechete nguva imwe neimwe. Iwo akawedzeredzwa-kuburitswa makapuru (Astagraf XL) kana akawedzeredzwa-mapiritsi mapiritsi (Envarsus XR) anowanzo kutorwa mangwanani ega ega pane isina chinhu mudumbu kweinenge 1 awa zvisati zvaitika kana kwekuseni kana angangoita 2 maawa mushure mekudya kwekuseni. Tora tacrolimus panguva imwechete (s) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora tacrolimus chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe uri kutora granules yekumiswa pamuromo, iwe uchafanirwa kuisanganisa neimba yekushisa yemvura usati washandisa. Isa 1 kusvika ku2 mashupuni (15 kusvika 30 milliliters) emvura mukapu ine granules. Sanganisa zvirimo wobva watora musanganiswa nemuromo kubva mukapu kana nesirinji yemuromo; usachengetedze musanganiswa kwenguva inotevera. Iyo granules haizonyungudike zvachose. Kana paine chero musanganiswa wakasara, wedzera 1 kusvika ku2 mashupuni (15 kusvika 30 milliliters) emvura kumusanganiswa uye nekukurumidza utore.

Medza macapuleti akasunungurwa-akasunungurwa uye mahwendefa akasunungurwa-akazara nemvura; usatsemure, kutsenga, kana kuvapwanya. Usavhure macomputer-ekuburitsa macapsule,

Chiremba wako anokuongorora iwe nekuchenjerera uye gadzirisa yako dosi pazvinodiwa. Taura nachiremba wako kazhinji nezvekuti unonzwa sei panguva yekurapwa kwako. Kumbira chiremba wako kana iwe uine chero mibvunzo nezve yakawanda tacrolimus yaunofanira kutora.

Zvigadzirwa zvakasiyana tacrolimus zvinoburitsa mushonga wacho zvakasiyana mumuviri wako uye hazvigone kushandiswa zvakasiyana. Ingotora tacrolimus chigadzirwa chakatemwa nachiremba wako uye usachinjira kune chakasiyana tacrolimus chigadzirwa kunze kwekunge chiremba wako ati unofanira kudaro.

Tacrolimus inogona chete kudzivirira kuramba kwekuiswa kwako chero bedzi iwe uri kutora mushonga. Ramba uchitora tacrolimus kunyangwe iwe uchinzwa zvakanaka. Usarega kutora tacrolimus usina kutaura nachiremba wako.

Tacrolimus zvakare dzimwe nguva inoshandiswa kurapa fistulizing chirwere cheCrohn (mamiriro umo muviri unorwisa kumhara kwetakiti rekugaya, zvichikonzera marwadzo, manyoka, kuonda, kupisa muviri, uye kuumbwa kwenzvimbo dzisina kujairika dzinobatanidza nzira yekugaya kune dzimwe nhengo kana ganda). Taura nachiremba wako nezve njodzi dzekushandisa mushonga uyu kurapa mamiriro ako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora tacrolimus,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune tacrolimus, chero mimwe mishonga, kana chero chimwe chezvimwe zvinoshandiswa muzvigadzirwa zvetacrolimus. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amiodarone (Nexterone, Pacerone); amphotericin B (Abelcet, Ambisome); angiotensin inoshandura enzyme (ACE) inhibitors senge benazepril (Lotensin, muLotrel), captopril, enalapril (Vasotec, muVaseretic), fosinopril, lisinopril (muPrinzide, muZestoretic), moexipril (Univasc, in Unopic) , muPrestalia), quinapril (Accupril, muQuinaretic), ramipril (Altace), kana trandolapril (muTarka); maantacid ane magnesium uye aluminium hydroxide (Maalox); mamwe maantibhakitiriya anosanganisira aminoglycosides senge amikacin, gentamicin, neomycin (Neo-Fradin), streptomycin, uye tobramycin (Tobi), uye macrolides akadai se clarithromycin (Biaxin), erythromycin (EES, E-Mycin, Erythrocin), uye troleandomycin (TAO. haisi kuwanikwa muUS); antifungal mishonga yakadai se clotrimazole (Lotrimin, Mycelex), fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), uye voriconazole (Vfend); angiotensin receptor blockers (ARBs) senge azilsartan (Edarbi, muEdbybyclor), makenduru (Atacand, muAtacand HCT), eprosartan (Teveten), irbesartan (Avapro, muAvalide), losartan (Cozaar, muHyzaar), olmesartan (Benicar muAzor, muBenicar HCT, muTribenzor), telmisartan (Micardis, muMicardis HCT, muTwynsta); boceprevir (Victrelis; haichawanikwi muU.S.); calcium chiteshi blockers senge diltiazem (Cardizem), nicardipine, nifedipine (Adalat, Procardia), uye verapamil (Calan, Verelan, muTarka); caspofungin (Cancidas); chloramphenicol; cimetidine (Tagamet); cisapride (Propulsid; haisi kuwanikwa muU.S.); cisplatin; danazol; mamwe ma diuretics ('mapiritsi emvura'); ganciclovir (Valcyte); mamwe mahormone ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, kuisa, kana majekiseni); mimwe mishonga yeHIV yakaita sedadososine (Videx); indinavir (Crixivan), lamivudine (Epivir); nelfinavir (Viracept), ritonavir (Norvir), stavudine (Zerit), uye zidovudine (Retrovir) lansoprazole (Prevacid); methylprednisolone (Medrol); metoclopramide (Reglan); mycophenolate (Cellcept); nefazodone; omeprazole (Prilosec); prednisone; rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); mimwe mishonga yekubatwa kwakadai se carbamazepine (Tegretol, Teril), phenobarbital, uye phenytoin (Dilantin, Phenytek); sirolimus (Rapamune), uye telaprevir (Incivek; haisisipo muU.S.). Chiremba wako angangoda kushandura kuyerwa kwemishonga yako kana kukutarisisa zvakanyatso chenjera mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne tacrolimus, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe uri kutora kana uchangomira kutora cyclosporine (Gengraf, Neoral, Sandimmune). Kana iwe wanga uchitora cyclosporine, chiremba wako angangokuudza kuti usatanga kutora tacrolimus kusvika maawa makumi maviri nemana mushure mekutora yako yekupedzisira dosi yecyclosporine. Kana iwe ukarega kutora tacrolimus, chiremba wako achakuudzawo iwe kumirira maawa makumi maviri nemaviri usati watanga kutora cyclosporine.
• udza chiremba wako uye wemishonga kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort kana schisandra sphenanthera zvigadzirwa. Usatore zvigadzirwa zvemakwenzi uchitora tacrolimus.
• udza chiremba wako kana iwe kana wakambove neQT syndrome (chinogarwa nhaka umo munhu anowanzove nekuwedzera kweQT) mashoma masosi e potassium, calcium, kana magnesium muropa rako, kurova kwemoyo zvisina kujairika, cholesterol zhinji, moyo , itsvo, kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe kana mumwe wako muchikwanisa kuve nepamuviri, shandisai zvinobudirira kudzora kubereka usati uye panguva yekurapwa netacrolimus. Kana iwe ukava nepamuviri uchitora tacrolimus, danaidza chiremba wako. Tacrolimus inogona kukuvadza fetus.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti uri kutora tacrolimus.
• iwe unofanirwa kuziva kuti kutora tacrolimus kunogona kuwedzera njodzi yekuti uchava nekenza yeganda. Zvidzivirire kubva kugomarara reganda nekurega kudzivirirwa zvisina kufanira kana kwenguva refu nechiedza chezuva kana mwenje ye ultraviolet (mibhedha yekuchenesa) uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen ine ganda rakakwirira rekudzivirira chinhu (SPF).
• usanwa zvinwiwa zvinodhaka paunenge uchitora tacrolimus yakawedzera-kuburitsa makapuru kana mapiritsi akaregedzwa. Doro rinogona kuita kuti mhedzisiro kubva kune tacrolimus iwedzere.
• iwe unofanirwa kuziva kuti tacrolimus inogona kukonzera kukwira kweropa. Chiremba wako anozotarisa yako yeropa nekuchenjerera, uye anogona kupa mishonga yekurapa yakakwira BP kana ikakura
• iwe unofanirwa kuziva kuti pane njodzi yekuti iwe unozoita chirwere cheshuga panguva yekurapa kwako netacrolimus. African American uye Hispanic varwere vakave nekuchinja kweitsvo vane njodzi yakanyanya kukura yekuve neshuga panguva yekurapwa kwavo netacrolimus. Udza chiremba wako kana iwe kana mumwe munhu mumhuri yako ane kana akambove nechirwere cheshuga. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza: kunyanyisa nyota; nzara yakanyanyisa; kugara uchiita weti; kusaona zvakanaka kana kuvhiringidzika.
• hauna majekiseni pasina kutaura nachiremba wako.

Dzivisa kudya mazambiringa mazambiringa kana kunwa jisi remuzambiringa paunenge uchitora tacrolimus.

Kana iyo yekukurumidza-kuburitsa kapuleti kana yemumuromo yekumisa dosi ikashaikwa, tora iyo nekukurumidza sezvauno rangarira iwe Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iyo yakawedzera-kuburitsa kapuleti dosi ikashaikwa, tora iyo dosi kana iri mukati maawa gumi nemana mushure mekushaya iyo dosi. Nekudaro, kana iri anopfuura maawa gumi nemana, svetuka iyo yakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iyo yekuwedzera-kuburitsa piritsi dhizaini ikashaikwa, tora iyo iyo iyo kana iri mukati maawa gumi nemashanu mushure mekushaya iyo dosi. Nekudaro, kana iri anopfuura maawa gumi nemashanu, svetuka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Tacrolimus inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• manyoka
• kuvimbiswa
• kusvotwa
• kurutsa
• chirungurira
• kurwadziwa nemudumbu
• kurasikirwa nenzara
• kunetseka kurara kana kuramba wakarara
• dzungu
• kushaya simba
• musana kana kurwadziwa kwemajoini
• kupisa, chiveve, kurwadziwa, kana kugwinha mumaoko kana tsoka

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, kana izvo zvataurwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukasira:

• kuderera kwekuita weti
• kurwadziwa kana kupisa pakuita weti
• kufema kwekufema, mikoko, mapundu, kana kuchenesa
• ganda rakachenuruka, kufema kwekufema, kana kurova kwemoyo nekukurumidza
• kuneta; kuwedzera uremu; kuzvimba kwemaoko, maoko, tsoka, makumbo, kana makumbo ezasi; kana kufema kwekufema
• kubuda ropa zvisina kujairika kana kupwanya
• kubatwa, kuona kushanduka, kurwadziwa nemusoro, kuvhiringidzika, kana kuzununguka kusingadzoreki kwechikamu chemuviri
• coma (kurasikirwa kwekuziva kwenguva yakati)

Tacrolimus inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika.http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• mikoko
• hope
• kusvotwa, kurutsa, uye manyoka
• kusadzora kusadzora kwechikamu chemuviri, kutemwa nemusoro, kuvhiringidzika, kusaenzana, uye kuneta zvakanyanya
• kuzvimba kwemaoko kana makumbo
• fever kana zvimwe zviratidzo zvehutachiona

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mimwe bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune tacrolimus.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Astagraf XL^®
• Envarsus XR^®
• Prograf^®

• FK 506