Infliximab jekiseni

Zvemukati

• Infliximab jekiseni zvigadzirwa zvinoshandiswa kugadzirisa zviratidzo zvehumwe autoimmune kusagadzikana (mamiriro umo immune system inorwisa zvikamu zvine hutano zvemuviri uye inokonzeresa kurwadziwa, kuzvimba, uye kukuvara) kusanganisira:
• Usati washandisa infliximab jekiseni chigadzirwa,
• Infliximab jekiseni zvigadzirwa zvinogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Zviratidzo zvinotevera hazvishamise, asi kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchitaona, kana iwo akanyorwa mune ZVINOKOSHA KUTI VANYENZESE kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukasika:

Infliximab jekiseni, infliximab-dyyb jekiseni, uye infliximab-abda jekiseni ndeye biologic mishonga (mishonga inogadzirwa kubva kune zvipenyu) Biosimilar infliximab-dyyb jekiseni uye infliximab-abda jekiseni zvakanyanya kufanana neiyo infliximab jekiseni uye inoshanda nenzira imwecheteyo se infliximab jekiseni mumuviri. Naizvozvo, izwi rokuti infliximab jekiseni zvigadzirwa richashandiswa kumiririra iyi mishonga mune iyi nhaurirano.

Infliximab jekiseni zvigadzirwa zvinogona kudzikisira kugona kwako kurwisa hutachiona uye kuwedzera mukana wekuti iwe utore hutachiona hwakakomba, kusanganisira hwakanyanya hutachiona, hutachiona, kana fungal hutachiona hunogona kupararira mumuviri wese. Zvirwere izvi zvingangoda kurapwa muchipatara uye zvinogona kukonzera kufa. Udza chiremba wako kana iwe uchiwanzo kuwana chero hutachiona hutachiona kana kana iwe uchifunga kuti ungave uine chero hutachiona hutachiona izvozvi. Izvi zvinosanganisira hutachiona hushoma (sekucheka kana maronda akavhurika), hutachiona hunouya nekuenda (hwakadai maronda anotonhora) uye hutachiona husingaperi husingaendi. Uyezve udza chiremba wako kana uine chirwere cheshuga kana chero mamiriro ezvinhu anokanganisa immune system yako uye kana uchigara kana wakambogara munzvimbo dzakadai seOhio kana Mississippi rwizi rwizi uko kwakanyanya fungal hutachiona hwanyanya. Kumbira chiremba wako kana iwe usingazive kana hutachiona hwanyanya munzvimbo yako. Uyezve udza chiremba wako kana uri kutora mishonga inoderedza mashandiro ezvirwere zvemuviri senge abatacept (Orencia); anakinra (Kineret); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); steroid senge dexamethasone, methylprednisolone (Medrol), prednisolone (Orapred ODT, Pediapred, Prelone), kana prednisone; kana tocilizumab (Actemra).

Chiremba wako anokucherechedza iwe nezviratidzo zvehutachiona panguva uye pfupi mushure mekurapa kwako. Kana iwe uine chero cheanotevera zviratidzo usati watanga kurapwa kwako kana kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge waita kurapwa, dana chiremba wako nekukurumidza: kushaya simba; vangadikitira; kunetseka kufema; huro inorwadza; kukosora; kukosora maburi eropa; kupindwa nechando; kuneta kwakanyanya; flu-kunge zviratidzo; inodziya, tsvuku, kana inorwadza ganda; manyoka; kurwadziwa mudumbu; kana zvimwe zviratidzo zvehutachiona.

Unogona kutapukirwa netibhii (TB, chirwere chakakomba chemapapu) kana hepatitis B (hutachiona hunokanganisa chiropa) asi usina zviratidzo zvechirwere. Mune ino kesi, infliximab jekiseni zvigadzirwa zvinogona kuwedzera njodzi yekuti hutachiona hwako huchawedzera uye uchaita zviratidzo. Chiremba wako achaita ongororo yeganda kuti aone kana uine hutachiona hweTB husingaite uye anogona kuraira kuongororwa kweropa kuti aone kana uine hutachiona hwehepatitis B. Kana zvichidikanwa, chiremba wako anokupa mishonga yekurapa hutachiona uhu usati watanga kushandisa infliximab jekiseni chigadzirwa. Udza chiremba wako kana wakambove neTB kana kuti wakambove neTB, kana iwe wakambogara kana kushanyira nzvimbo ine TB yakajairika, kana kana iwe wakambenge uri pane mumwe munhu ane TB. Kana iwe uine chero anotevera zviratidzo zveTB, kana kana iwe ukaita chero eapi eaya maratidziro panguva yekurapwa kwako, fonera chiremba wako nekukasira: kukosora, kuonda, kurasikirwa kwemhasuru toni, fivha, kana husiku hweziya. Zvakare fonera chiremba wako nekukasira kana uine chimwe chezviratidzo zvehepatitis B kana kana iwe uchikura chimwe chezviratidzo izvi panguva kana mushure mekurapwa kwako: kuneta zvakanyanya, kuita yero kweganda kana maziso, kurasikirwa nenzara, kuda kurutsa kana kurutsa, tsandanyama aches, weti yakasviba, kufamba-kweuvara-ura kufamba, fivha, kutonhora, kurwadziwa mudumbu, kana kuputika.

Vamwe vana, vachiri kuyaruka, uye vechidiki vakuru vakagashira infliximab jekiseni chigadzirwa kana mishonga yakafanana vakagomarara zvakanyanya kana kutyisidzira hupenyu kenza inosanganisira lymphoma (kenza inotanga mumasero anorwisa hutachiona). Vamwe vechidiki uye vechidiki varume vakuru vakatora infliximab chigadzirwa kana mishonga yakafanana vakagadzira hepatosplenic T-cell lymphoma (HSTCL), chirwere chakakomba chekenza icho chinowanzo kukonzera kufa mukati menguva pfupi yenguva.Vazhinji vevanhu vakagadzira HSTCL vairapwa chirwere cheCrohn (mamiriro ezvinhu umo muviri unorwisa kumhara kwegwara rekudya, zvichikonzera marwadzo, manyoka, kuonda, nefivha) kana ulcerative colitis (mamiriro anokonzera kuzvimba nemaronda. mumutsara wekoloni [ura hukuru] uye rectum) ine infliximab jekiseni chigadzirwa kana mushonga wakafanana pamwe nemumwe mushonga unonzi azathioprine (Azasan, Imuran) kana 6-mercaptopurine (Purinethol, Purixan). Udza chiremba wemwana wako kana mwana wako akambova nemhando ipi neipi yekenza. Kana mwana wako akatanga chero eaya maratidziro panguva yekurapwa kwake, danai chiremba wake nekukasira: kusanzwisisika kuonda kuzvimba gland mumutsipa, underarms, kana kugomera; kana kupwanya kuri nyore kana kubuda ropa. Taura nachiremba wemwana wako nezve njodzi dzekupa infliximab jekiseni chigadzirwa kumwana wako.

Chiremba wako kana wemishonga achakupa gwaro reruzivo rwevarwere (reMedicine Gwara) paunotanga kurapwa nechigadzirwa chejekiseni re infliximab uye pese paunogamuchira mishonga. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekushandisa infliximab jekiseni chigadzirwa.

Infliximab jekiseni zvigadzirwa zvinoshandiswa kugadzirisa zviratidzo zvehumwe autoimmune kusagadzikana (mamiriro umo immune system inorwisa zvikamu zvine hutano zvemuviri uye inokonzeresa kurwadziwa, kuzvimba, uye kukuvara) kusanganisira:

• rheumatoid arthritis (mamiriro umo muviri unorwisa majoini awo, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) iri kurapwawo ne methotrexate (Rheumatrex, Trexall),
• Chirwere cheCrohn (mamiriro umo muviri unorwisa maburi edumbu, zvichikonzera marwadzo, manyoka, kuonda, nefivha) kuvanhu vakuru nevana vane makore matanhatu ekuberekwa kana asina kuzobudirira kana uchirapwa neimwe mishonga,
• ulcerative colitis (mamiriro anokonzeresa kuzvimba uye maronda mumucheka wemuhomba wakakura) muvakuru uye vana vane makore matanhatu ekuberekwa kana zvisati zvagadziriswa kana zvichibatwa nemimwe mishonga,
• ankylosing spondylitis (mamiriro umo muviri unorwisa majoini emuzongoza pamwe nedzimwe nzvimbo zvichikonzera kurwadziwa nekukuvara kwemajoini),
• plaque psoriasis (chirwere cheganda umo mutsvuku, makanda makanda anoumbwa pane dzimwe nzvimbo dzomuviri) muvanhu vakuru kana kumwe kurapa kusiri kukodzera,
• uye psoriatic arthritis (mamiriro anokonzera kurwadza kwemajoini uye kuzvimba uye zviyero paganda).

Infliximab jekiseni zvigadzirwa zviri mukirasi yemishonga inonzi tumor necrosis factor-alpha (TNF-alpha) inhibitors. Ivo vanoshanda nekudzivirira chiito cheTNF-alpha, chinhu chiri mumuviri chinokonzera kuzvimba.

Infliximab jekiseni zvigadzirwa zvinouya sehupfu hunofanira kusanganiswa nemvura isina kuchena uye inoiswa mukati-mukati (mutsinga) nachiremba kana mukoti. Inowanzo kupihwa muhofisi yechiremba kamwe chete pamasvondo maviri kusvika masere, kazhinji pakutanga kwekurapa kwako uye kashoma apo kurapwa kwako kunoenderera. Zvinotora anenge maawa maviri kuti iwe ugamuchire yako yese dosi yeiyo infliximab, jekiseni chigadzirwa.

Infliximab jekiseni zvigadzirwa zvinogona kukonzera kukomba kwakakomba kusagadzikana, kusanganisira allergic reaction panguva yekuwedzeredzwa uye kwemaawa maviri mushure. Chiremba kana mukoti anozokutarisa panguva ino kuve nechokwadi kuti hausi kuita zvakakomba kumushonga. Iwe unogona kupihwa imwe mishonga yekurapa kana kudzivirira maitiro kune iyo infliximab jekiseni chigadzirwa. Udza chiremba wako kana mukoti nekukasira kana iwe ukaona chero chinotevera chezviratidzo panguva kana pfupi mushure mekumukiswa: mikoko; mapundu; kuvava; kuzvimba kwechiso, maziso, muromo, huro, rurimi, miromo, maoko, tsoka, makumbo, kana makumbo ezasi; kunetseka kufema kana kumedza; kutsvaira; dzungu; kufenda; kupindwa nechando; chills; pfari; kurasikirwa kwemaonero; uye kurwadziwa muchipfuva.

Infliximab jekiseni zvigadzirwa zvinogona kubatsira kudzora zviratidzo zvako, asi hazvizoporese mamiriro ako. Chiremba wako anokucherekedza nokungwarira kuti uone kuti infliximab jekiseni zvigadzirwa zvinoshanda sei kwauri. Kana iwe uine rheumatoid arthritis kana chirwere cheCrohn, chiremba wako anogona kuwedzera huwandu hwemishonga yaunogamuchira, kana zvichidikanwa. Kana iwe uine chirwere cheCrohn uye mamiriro ako asina kuvandudzwa mushure memasvondo gumi nemana, chiremba wako anogona kumira kukurapa iwe neiyo infliximab jekiseni chigadzirwa. Zvakakosha kuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako.

Infliximab jekiseni zvigadzirwa zvakare dzimwe nguva zvinoshandiswa kurapa Behcet's syndrome (maronda mumuromo uye panhengo yekubereka uye kuzvimba kwenzvimbo dzakasiyana dzemuviri). Taura nachiremba wako nezve njodzi dzinogona kuitika dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa infliximab jekiseni chigadzirwa,

• udza chiremba wako uye wemishonga kana uri weergoria kune infliximab, infliximab-axxq, infliximab-dyyb, infliximab-abda, chero mishonga inogadzirwa kubva murine (mbeva) mapuroteni, chero mimwe mishonga, kana chero chinhu chinosanganiswa mu infliximab, infliximab-dyyb, kana infliximab-abda jekiseni. Bvunza chiremba wako kana wemishonga kana iwe usingazive kana mushonga iwe wauri weergiki wakagadzirwa kubva murine mapuroteni. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu uye chero cheanotevera: anticoagulants (ropa rakatetepa) senge warfarin (Coumadin), cyclosporine (Gengraf, Neoral, Sandimmune), uye theophylline (Elixophyllin, Theo-24, Theochron) . Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove nemoyo wekutadza (mamiriro apo moyo usingakwanise kupomba ropa rakakwana kune mamwe mativi emuviri). Chiremba wako anogona kukuudza kuti usashandise infliximab jekiseni chigadzirwa.
• udza chiremba wako kana iwe wakamborapwa nephototherapy (kurapwa kwe psoriasis kunosanganisira kuburitsa ganda kune ultraviolet mwenje) uye kana iwe kana wakambove nechirwere chinokanganisa system yako yetsinga, senge multiple sclerosis (MS; kurasikirwa kwe kufambidzana, kushaya simba, uye kuvevesa nekuda kwekukuvara kwetsinga), Guillain-Barre syndrome (kushaya simba, kurira, uye kuoma mitezo nekuda kwekukuvara kwetsinga kamwe kamwe) kana optic neuritis (kuzvimba tsinga inotumira mameseji kubva kuziso kuenda kuuropi); chiveve, kupisa kana kugwinha mune chero chikamu chemuviri wako; pfari; chisingaperi obstructive pulmonary chirwere (COPD; boka rezvirwere zvinokanganisa mapapu nemumhepo); chero mhando yekenza; matambudziko ekubuda ropa kana zvirwere zvinokanganisa ropa rako; kana chirwere chemwoyo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uchishandisa infliximab jekiseni chigadzirwa, fonera chiremba wako. Kana iwe ukashandisa infliximab jekiseni chigadzirwa panguva yako yepamuviri, ita chokwadi chekutaura nachiremba wemwana wako nezve izvi mushure mekunge mwana wako aberekwa. Mwana wako angangoda kugamuchira mamwe majekiseni kwapfuura nguva.
• kana iwe uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikushandisa infliximab jekiseni chigadzirwa.
• udza chiremba wako kana uchangobva kugamuchira mushonga. Uyezve bvunza nachiremba wako kuti uone kana iwe uchida kugamuchira chero majekiseni. Hauna majekiseni pasina kutaura nachiremba wako. Izvo zvakakosha kuti vakuru nevana vagamuchire ese majekiseni-akakodzera majekiseni vasati vatanga kurapwa ne infliximab.
• iwe unofanirwa kuziva kuti iwe unogona kunge wakanonoka kukanganiswa nemagetsi mazuva matatu kusvika gumi nemaviri mushure mekunge wagashira infliximab jekiseni chigadzirwa. Udza chiremba wako kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona kurapwa maronda kana mhasuru; kupindwa nechando; mapundu; mikoko; kuvava; kuzvimba kwemaoko, kumeso, kana miromo; kunetsa kumedza; huro inorwadza; uye musoro.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Infliximab jekiseni zvigadzirwa zvinogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kusvotwa
• chirungurira
• musoro
• dzihwa
• zvigamba zvichena mumuromo
• kusangana nekutsi kwemukadzi, kupisa, uye kurwadziwa, kana zvimwe zviratidzo zvehutachiona hwembiriso
• kufashaira

Mimwe mhedzisiro inogona kuve yakakomba. Zviratidzo zvinotevera hazvishamise, asi kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchitaona, kana iwo akanyorwa mune ZVINOKOSHA KUTI VANYENZESE kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukasika:

• chero mhando yekumhanyisa, inosanganisira kumhanyisa pamatama kana maoko zvinowedzera muzuva
• kurwadziwa pachipfuva
• kurova kwemoyo zvisina kujairika
• kurwadziwa mumaoko, musana, mutsipa, kana shaya
• kurwadziwa nemudumbu
• kuzvimba kwetsoka, makumbo, dumbu, kana makumbo ezasi
• kamwe kamwe kuwedzera uremu
• mweya wekufema
• kusaona zvakanaka kana kuona shanduko
• kamwe kamwe kushaya simba kweruoko kana gumbo (kunyanya kune rimwe divi remuviri) kana rechiso
• mhasuru kana kurwadziwa kwemajoini
• chiveve kana kugwinha mune chero chikamu chemuviri
• kuvhiringidzika kamwe kamwe, kunetseka kutaura, kana kunetseka kunzwisisa
• pakarepo dambudziko rekufamba
• dzungu kana kupera simba
• kurasikirwa kwechiyero kana kubatana
• pakarepo, musoro wakakomba
• pfari
• yero yeganda kana maziso
• weti yakasviba
• kurasikirwa nenzara
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• kupwanya kusingawanzo kana kubuda ropa
• ropa muzvigaro
• ganda rakachenuruka
• kutsvuka, zvigamba kana bundu-rakazara mapundu paganda

Injectiabab jekiseni inogona kuwedzera njodzi yako yekukudziridza lymphoma (kenza inotanga mumasero anorwisa hutachiona) uye mamwe makenza. Taura nachiremba wako nezve njodzi dzekugamuchira infliximab jekiseni chigadzirwa.

Infliximab jekiseni zvigadzirwa zvinogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchishandisa mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chiremba wako anozochengeta mishonga muhofisi yake.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuyedzwa kwerabhoritari kuti utarise mhinduro yemuviri wako kune infliximab jekiseni chigadzirwa.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Avsola^® (Infliximab-axxq)
• Inflectra^® (Infliximab-dyyb)
• Remicade^® (Infliximab)
• Renflexis^® (Infliximab-abda)

• Anti-bundu Necrosis Factor-alpha
• Anti-TNF-alpha
• cA2