Munyori: Janice Evans
Zuva Rekusika: 27 Chikunguru 2021
Gadziridza Zuva: 15 Mbudzi 2024
Anonim
Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson’s disease
Vhidhiyo: Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson’s disease

Zvemukati

Rasagiline inoshandiswa yoga kana musanganiswa nemumwe mushonga kurapa zviratidzo zvehosha yaPasinson (chirwere chinofambira mberi zvishoma nezvishoma chehurongwa hwemitsipa chinokonzeresa kumeso kusingataure, kudedera pakuzorora, kunonoka kwekufamba, kufamba nenhanho dzekutsvedza, kumira kwakamira uye mhasuru kushaya simba). Rasagiline iri mukirasi yemishonga inonzi monoamine oxidase (MAO) mhando B inhibitors. Inoshanda nekuwedzera huwandu hwezvimwe zvinhu zvakasikwa muuropi.

Rasagiline inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva kana pasina chikafu. Tora rasagiline kwakatenderedza nguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora rasagiline chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Chiremba wako anogona kukutanga iwe pane yakaderera dosi ye rasagiline uye anogona kuwedzera yako dosi inoenderana nemhinduro yemuviri wako kumushonga uyu.


Usarega kutora rasagiline usina kutaura nachiremba wako. Chiremba wako angangoderedza dhizaini yako zvishoma nezvishoma. Kana ukangoerekana warega kutora rasagiline, unogona kusangana nezviratidzo zvekuregera zvakaita sefivha; kuomarara kwemhasuru; kusagadzikana, kudedera, kana kushomeka kwekubatana; kana shanduko mukuziva. Udza chiremba wako kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchizoita dose.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora rasagiline,

  • udza chiremba wako uye wemishonga kana uri weergoria kune rasagiline, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi e rasagiline. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora chikosoro uye zvigadzirwa zvinotonhora zvine dextromethorphan (DM; Delsym, Bata, Robitussin CoughGels, Vicks 44 Cough Relief, muRobitussin DM, vamwe), cyclobenzaprine (Flexeril), meperidine (Demerol), methadone (Dolophine, Methadose ), propoxyphene (Darvon, muDarvocet-N, vamwe), St. John's wort, kana tramadol (Ultram, muUltracet). Uyezve udza chiremba wako kana uri kutora MAO inhibitors senge phenelzine (Nardil), selegiline (Eldepryl), kana tranylcypromine (Parnate) kana kuti warega kuvatora mukati memavhiki maviri apfuura. Chiremba wako anogona kukuudza kuti usatora rasagiline kana uri kutora imwe kana yakawanda yemishonga iyi.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amphetamines (Adderall, Dexedrine, DextroStat); mishonga inodzvinyirira; cimetidine (Tagamet); decongestant akaiswa muziso kana mhino; Kudya kana uremu-kudzora zvigadzirwa zvine ephedrine; fluoroquinolone antibiotics inosanganisira ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), norfloxacin (Noroxin), uye ofloxacin (Floxin); fluvoxamine (Luvox); mishonga yekurapa asthma; mishonga yekurapa yakakwira BP; mishonga yekurapa chirwere chepfungwa; mishonga yekurapa kurwadziwa; phenylpropanolamine (haisipo muU.S.); pseudoephedrine (PediaCare, Sudafed, Suphedrine, vamwe); uye ticlopidine (Ticlid). Udza chiremba wako kana uri kutora fluoxetine (Prozac, Sarafem) kana kuti warega kuitora mukati memasvondo mashanu apfuura. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana wakambove neBP yakakwira, chirwere chepfungwa kana psychosis; itsvo, kana chirwere chechiropa.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora rasagiline, fonera chiremba wako.
  • iwe unofanirwa kuziva kuti rasagiline inogona kukonzeresa dzungu, huremu husina musoro, kusvotwa, kudikitira, nekufenda kana iwe ukasimuka nekukurumidza kubva panzvimbo yekunyepa. Izvi zvinowanzoitika mukati memwedzi miviri yekutanga yekutora rasagiline. Kuti udzivise dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka.
  • iwe unofanirwa kuziva kuti rasagiline inogona kukonzera zvakakomba, kutyisidzira hupenyu kukwirisa kweropa kana uchitorwa nemimwe mishonga kana chikafu. Ngwarira tevera kuraira kwechiremba wako nezve mishonga uye zvekudya zvinofanirwa kudzivirirwa. Fonera chiremba wako ipapo ipapo kana iwe uine musoro wakakomba, kusaona zvakanaka, kana chero chimwe chezviratidzo zvakanyorwa pazasi semhedzisiro yakakomba mhedzisiro.
  • iwe unofanirwa kuziva kuti vanhu vane chirwere cheParkinson vane njodzi yakanyanya yemelanoma (rudzi rwegomarara reganda) kupfuura vanhu vasina chirwere cheParkinson. Hazvizivikanwe kana njodzi iyi yakawedzerwa ichikonzerwa nechirwere chePasinson, mishonga inoshandiswa pachirwere chePasinson senge rasagiline, kana zvimwe zvinhu. Iwe unofanirwa kugara uchishanyirwa nedermatologist kuti uongorore ganda rako kune melanoma.
  • iwe unofanirwa kuziva kuti vamwe vanhu vakatora rasagiline kana mishonga yakafanana kurapa chirwere cheParkinson vakasangana nekukurudzirwa kwakanyanya kwekubhejera, kuwedzera kuda kurara pabonde, uye zvimwe zvido zvavakatadza kudzora. Udza chiremba wako kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona.

Iwe unozofanirwa kudzivirira kudya chikafu chine huwandu hwakanyanya hwe tyramine, senge chezi dzakura (semuenzaniso, Stilton kana bhuruu chizi) panguva yekurapa kwako ne rasagiline. Taura nachiremba wako kana chiremba wezvekudya nezve izvo zvekudya zvaunofanirwa kudzivirira panguva yekurapa kwako kana kana iwe usinganzwe mushe mushure mekudya kana kunwa zvimwe zvekudya uchitora rasagiline.


Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.Darika dosi rakarasika uye tora yako inotevera dosi panguva yakajairwa zuva rinotevera.

Rasagiline inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • nyoro musoro
  • kubatana kana kurwadziwa kwemutsipa
  • chirungurira
  • kusvotwa
  • kurutsa
  • kurwadziwa nemudumbu
  • kuvimbiswa
  • manyoka
  • kurasikirwa nenzara
  • kuonda
  • furu-kunge zviratidzo
  • kupindwa nechando
  • vangadikitira
  • dzvuku, kuzvimba, uye / kana maziso anotsunya
  • muromo wakaoma
  • matadza kuzvimba
  • kusagadzikana, kudedera, kana kushomeka kwekubatana
  • kusazvipira, kudzokorora kufamba kwemuviri
  • kushaya simba
  • hope
  • hope dzisina kujairika
  • kuora mwoyo
  • kurwadziwa, kupisa, chiveve, kana kugwinha mumaoko kana tsoka
  • mapundu
  • kupwanya kana ruvara rwepepuru paganda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

  • kurwadziwa nemusoro zvakanyanya
  • kusaona zvakanaka
  • pfari
  • kurwadziwa pachipfuva
  • kutadza kufema kana kunetseka kufema
  • kuvhiringidzika
  • kusaziva chinhu
  • kutaura kunonoka kana kuoma
  • dzungu kana kupera simba
  • kushaya simba kana kushama ruoko kana gumbo
  • kufungidzira (kuona zvinhu kana kunzwa manzwi zvisipo)
  • kusagadzikana kwakanyanya
  • kunetseka kufunga zvakajeka kana kunzwisisa chokwadi

Rasagiline inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.


Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zve rasagiline ovhadhozi zvinogona kuitika sekupedzisira se1 kana mazuva maviri mushure mekuwedzeredza. Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kutsimwaira
  • dzungu
  • kupera simba
  • kugumbuka
  • kusagadzikana
  • kusagadzikana kana kusagadzikana
  • kurwadziwa nemusoro zvakanyanya
  • kuona zvinhu zvisizvo
  • kuvhiringidzika
  • kurasikirwa kwekubatana
  • kunetseka kushama muromo
  • yakaoma muviri spasm iyo inogona kusanganisira arched kumashure
  • kutsvinya mhasuru
  • pfari
  • kurasikirwa kwekuziva
  • kukurumidza kana kusajairika moyo kurova
  • kurwadziwa munzvimbo iri pakati pe dumbu ne chipfuva
  • kunetseka kufema kana kunonoka kufema
  • manyoka
  • kupindwa nechando
  • vangadikitira
  • inotonhorera, yakanamatira ganda
  • kubvunda
  • kuwedzera muhukuru hwemudzidzi (denderedzwa dema pakati peziso)

Chengetedza zvese zvakagadzwa nachiremba wako.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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