Munyori: Joan Hall
Zuva Rekusika: 1 Kukadzi 2021
Gadziridza Zuva: 20 Mbudzi 2024
Anonim
Brian Druker (OHSU) Part 1: Imatinib (Gleevec): A Targeted Cancer Therapy
Vhidhiyo: Brian Druker (OHSU) Part 1: Imatinib (Gleevec): A Targeted Cancer Therapy

Zvemukati

Imatinib inoshandiswa kurapa mamwe marudzi eleukemia (gomarara rinotanga mumasero machena eropa) uye mamwe kanzira uye kusagadzikana kwemasero eropa. Imatinib inoshandiswawo kurapa mamwe marudzi ematumbo stromal tumarara (GIST; mhando yemota inokura mumadziro enzira dzekugaya uye inogona kupararira kune mamwe mativi emuviri). Imatinib inoshandiswawo kurapa dermatofibrosarcoma protuberans (bundu rinoumba pasi pechikamu chepamusoro cheganda) apo bundu risingakwanise kubviswa nekuvhiya, rapararira kune dzimwe nhengo dzemuviri, kana kudzoka mushure mekuvhiyiwa. Imatinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Imatinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe nekudya uye girazi hombe remvura kamwe kana kaviri pazuva. Tora imatinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora imatinib chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Medza mapiritsi akazara; usatsvage kana kuapwanya. Kana iwe ukabata kana ukasangana zvakananga nepiritsi rakapwanyika, geza nzvimbo yacho zvakakwana.

Kana iwe usingakwanise kumedza imatinib mahwendefa, unogona kuisa ese mahwendefa aunoda kweimwe dhizaizi mugirazi remvura kana muto weapuro. Shandisa makumi mashanu emamirilita (zvishoma pasi pe2 ounces) emvura kune yega 100-mg piritsi uye mazana maviri emamirilita (zvishoma pasi peanomwe maoice) emvura kune yega 400-mg piritsi. Sungai nekapu kusvikira mapiritsi apwanyika zvachose uye munwe musanganiswa ipapo.

Kana chiremba wako akakuudza kuti utore 800 mg ye imatinib, iwe unofanirwa kutora maviri ema 400-mg mapiritsi. Usatore masere mapiritsi e100-mg. Hwendefa rekuputira rine iron, uye iwe uchagamuchira yakawandisa iron kana iwe ukatora masere e100-mg mapiritsi.

Chiremba wako anogona kuwedzera kana kudzikisa dhizaini yako yematinib panguva yekurapa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye pamhedzisiro yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora imatinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora imatinib usina kutaura nachiremba wako.


Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora imatinib,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune imatinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi ematinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora.Ive neshuwa yekutaura chero eanotevera: acetaminophen (Tylenol), alprazolam (Xanax), amlodipine (Norvasc, muCaduet, Lotrel, Tribenzor, vamwe), atazanavir (Reyataz), atorvastatin (Lipitor, muCaduet), carbamazepine (Carbatrol, Equetro, Tegretol, vamwe), clarithromycin (Biaxin, mu Prevpac), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone, ergotamine (Ergomar, muMigergot, Cafergot), erythromycin (EES, Eryc, Eryipine, vamwe), , fentanyl (Duragesic, Subsys, Fentora, vamwe), fosphenytoin (Cerebyx), indinavir (Crixivan), iron, kana simbi ine zvinowedzera, isradipine, itraconazole (Onmel, Sporanox), ketoconazole, lovastatin (Altoprev), metoprolol (Lopro XL, muDutoprol), nefazodone, nelfinavir (Viracept), nicardipine (Cardene), nifedipine (Adalat CC, Procardia, vamwe), nimodipine (Nymalize), nisoldipine (Sular), oxcarbazepine (Oxtellar XR, Trileptal), phenyarin Dilantin, Phenytek), pimozide (Orap), primidone (Mysoline), qui nidine (muNuedexta), rifabutin (Mycobutin), rifampin (rifadin, rimactane, muRifamate, Rifater), ritonavir (Norvir, muKaletra, Technivie, Viekira), saquinavir (Fortovase, Invirase), simvastatin (Zocor, sirolimus (Rapamune), tacrolimus (Astagraf XL, Envarsus XR, Prograf), telithromycin, triazolam (Halcion), voriconazole (Vfend), uye warfarin (Coumadin, Jantoven). Mimwe mishonga yakawanda inogona zvakare kubatana ne imatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
  • udza chiremba wako kana iwe kana wakambove nemoyo, mapapu, utachiona, itsvo, kana chirwere chechiropa.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe uchafanirwa kutora bvunzo yepamuviri usati watanga kurapwa, Iwe haufanire kuve nepamuviri iwe paunenge uchitora imatinib uye kwemazuva gumi nemana mushure meyako yekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe ukava nepamuviri uchitora imatinib, danaidza chiremba wako. Imatinib inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa iwe paunenge uchitora imatinib uye kwemwedzi mumwe mushure mekupedzisira kwezita rako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora imatinib.
  • iwe unofanirwa kuziva kuti imatinib inogona kukuita dzungu, kurara, kana kukonzera kuona kwakashata. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.


Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Imatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • kusvotwa
  • kurutsa
  • chinja munzira iyo zvinhu zvinonaka
  • maronda emuromo kana kuzvimba mukati memuromo
  • kurasikirwa nenzara
  • kuonda
  • chirungurira kana kuzvimbaradza
  • muromo wakaoma
  • musoro
  • kubatana kuzvimba kana kurwadziwa
  • kurwadziwa kwepfupa
  • mhasuru, mhasuru, kana kurwadziwa
  • kurira, kupisa. kana kunanzva kunzwa paganda
  • kunetseka kurara kana kuramba wakarara
  • vangadikitira
  • maziso ane misodzi
  • ziso repingi
  • kufashaira
  • ganda rakaoma
  • mapundu
  • kuvava
  • nzara inoshanduka
  • kurasikirwa nevhudzi

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi fonera chiremba wako nekukasira:

  • kuzvimba kwakakomberedza maziso
  • kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi
  • kamwe kamwe kuwedzera uremu
  • mweya wekufema
  • nekukurumidza, zvisina kujairika, kana kurova kurova kwemoyo
  • kukosora pingi kana ropa rinobuda ropa
  • kuwedzera weti, kunyanya husiku
  • kurwadziwa pachipfuva
  • peeling, blister, kana kudurura ganda
  • yero yeganda kana maziso
  • ropa muchitsiko
  • kupwanya kusingawanzo kana kubuda ropa
  • furu-kunge zviratidzo, huro, kupisa, kupisa, uye zvimwe zviratidzo zvehutachiona
  • kuneta zvakanyanya kana kushaya simba
  • kurwadziwa mumimba kana kuzvimba

Imatinib inogona kunonoka kukura muvana. Chiremba wemwana wako anozotarisa kukura kwake zvakanaka. Taura nachiremba wemwana wako nezve njodzi dzekupa imatinib kumwana wako.

Imatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kusvotwa
  • kurutsa
  • manyoka
  • mapundu
  • kuzvimba
  • kuneta zvakanyanya
  • tsandanyama kana mhasuru
  • marwadzo emudumbu
  • musoro
  • kurasikirwa nenzara

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune imatinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Gleevec®
Yekupedzisira Yakagadziridzwa - 03/15/2020

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