Sapropterin

Zvemukati

• Usati watora sapropterin,
• Sapropterin inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi fonera chiremba wako nekukasira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Sapropterin inoshandiswa pamwe neyakaganhurirwa chikafu kudzora ropa phenylalanine mazinga muvakuru uye vana 1 mwedzi zera uye vakuru vane phenylketonuria (PKU; mamiriro ekuberekwa umo phenylalanine inogona kuvaka muropa uye inokonzeresa huchenjeri uye kuderera kwekugona tarisa, rangarira, uye ronga ruzivo). Sapropterin inoshanda chete kune vamwe vanhu vane PKU, uye nzira chete yekuudza kana sapropterin ichizobatsira mumwe murwere kupa mushonga kwenguva yakati uye kuona kana yake phenylalanine level ichiderera. Sapropterin iri mukirasi yemishonga inonzi cofactors. Inoshanda nekubatsira muviri kuputsa phenylalanine saka haizovake muropa.

Sapropterin inouya sehwendefa uye sehupfu hunosanganiswa nechikafu chemvura kana chinyoro uye kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva nechikafu. Tora sapropterin panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora sapropterin chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe usingakwanise kumedza mapiritsi, isa nhamba yemapiritsi epapropterin awakaudzwa kuti utore mukapu ine ma4 ounces (1/2 kusvika 1 mukombe kana 120 kusvika 240 milliliters) emvura kana muto wemaapuro Simbisai musanganiswa kana kupwanya mapiritsi nechipunu kuti mapiritsi asungunuke. Mahwendefa anogona kusanyungudika zvachose; panogona kunge paine zvidimbu zvidiki zvehwendefa zvinoyangarara pamusoro pemvura. Kana mapiritsi achinyungudika, inwa musanganiswa wese. Kana zvidimbu zvemapiritsi zvikaramba zviri mumukombe mushure mekunwa musanganiswa, dururira mvura yakawanda kana muto wemaapuro mumukombe uye nekunwa kuti uve nechokwadi chekuti unomedza mishonga yese. Ive neshuwa yekunwa musanganiswa wese mukati memaminitsi gumi nemashanu mushure mekuigadzirira. Mahwendefa eSapropterin anokwanisawo kupwanywa nekusanganiswa nezvikafu zvakapfava zvakaita seapurosiuce uye pudding.

Kugadzirira sapropterin poda, wedzera zvirimo mupaketi mapaketi (s) ane 4 kusvika ku8 maunzi (1/2 kusvika 1 mukombe kana 120 kusvika 240 mamirilita) emvura kana muto wemaapuro, kana zvishoma zvishoma zvinyoro chikafu chakadai seapuraisauce kana pudding. Sanganisa hupfu mune chikafu kana chinyoro zvakanaka kwazvo kusvikira hupfu hwanyungudika zvachose. Ive neshuwa yekunwa kana kudya iyo yose musanganiswa kuti iwe ugowana iyo yakazara dhosi. Idya kana kunwa musanganiswa mukati memaminitsi makumi matatu uchigadzirira.

Kana iwe uri mubereki kana muchengeti uchipa hupfu kumwana anorema mapaundi makumi maviri (10 kg) kana pasi, iwe uchafanirwa kuwana mirawo chaiyo kubva kuna chiremba nezvekuti ingani mvura kana muto wemaapuro waungashandisa, uye yakawanda sei musanganiswa wekupa kumwana wako. Edza huwandu hwemvura kana muto wemaapuro wauri kushandisa nekapu yemushonga uye shandisa syringe yemumuromo yekuyera uye kupa muyero kumwana. Kanda chero musanganiswa wakasara mushure mekupihwa muyero.

Chiremba wako anozokutangira pane adose ye sapropterin uye anozotarisa yako yeropa phenylalanine level nguva dzose. Kana yako phenylalanine nhanho ikasadzikira, chiremba wako anogona kuwedzera yako dosi yesapropterin. Kana yako phenylalanine nhanho ikasadzikira mushure memwedzi mumwe wekurapwa nedosi yakakura yesapropterin, iwe nachiremba wako muchaziva kuti mamiriro enyu haapindure kune sapropterin. Chiremba wako anokuudza kuti rega kutora mushonga.

Sapropterin inogona kubatsira kudzora ropa phenylalanine mazinga, asi haizorape PKU. Ramba uchitora sapropterin kunyangwe iwe uchinzwa zvakanaka. Usarega kutora sapropterin usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora sapropterin,

• udza chiremba wako uye wemishonga kana uri weergoria kune sapropterin kana chero mumwe mushonga.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero cheanotevera: levodopa (muSinemet, muStalevo); methotrexate (Otrexup, Rasuvo, Trexall, vamwe); PDE5 inhibitors sildenafil (Revatio, Viagra), tadalafil (Cialis), uye vardenafil (Levitra); proguanil (muMalarone), pyrimethamine (Daraprim), uye trimethoprim (Primsol, muBactrim, Septra). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove neanorexia (chirwere chekudya umo munhu anodya zvishoma uye / kana kurovedza zvakanyanya kuti achengetedze kunyangwe huremu hwemuviri hunofungidzirwa hwakajairwa kune rake zera uye kukwirira) kana chero imwe mamiriro zvinokonzeresa kuti urege kudya zvinovaka muviri, kana chiropa kana chirwere cheitsvo.
• udza chiremba wako kana uine fivhiri kana iwe ukarwara chero nguva panguva yekurapwa kwako. Fivha uye chirwere zvinogona kukanganisa yako phenylalanine level, saka chiremba wako angangoda kugadzirisa yako dosi yesapropterin.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora sapropterin, fonera chiremba wako.

Iwe unofanirwa kuenderera uchitevera yakaderera phenylalanine chikafu paunenge uchitora sapropterin. Tevedza zvirevo zvechiremba wako nezvehutano zvinovaka. Usachinje kudya kwako nenzira ipi zvayo usingatauri nachiremba wako kana nyanzvi yezvokudya.

Kana iwe uchirangarira iro rakarasika dosi gare gare zuva rimwe chetero, tora iro rakarasika dosi nekukurumidza kana uchinge warangarira nezvaro. Nekudaro, kana iwe ukasarangarira kusvika zuva rinotevera, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore inopfuura imwechete dhizaini mune rimwe zuva kana kutora dhivhosi yakapetwa kuti uwane imwe yakarasika.

Sapropterin inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kusvotwa
• kurutsa
• kurwadziwa nemudumbu
• musoro
• kukosora, kurwadziwa pahuro, kana kutonhora zviratidzo
• kutenderera, kufamba famba, kana kutaura zvakawandisa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi fonera chiremba wako nekukasira:

• kufema, kupfupika kwemweya wekufema, kukosora, kumhanyisa, kusvotwa, kuputika
• kurwadziwa munzvimbo yepamusoro mudumbu, kuda kurutsa, kurutsa, dema, kunonoka kana chigaro chine ropa, kurutsa ropa

Sapropterin inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze munzvimbo inotonhorera, yakaoma, kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi kana mumota). Usabvisa iyo desiccant (kadiki kapaketi inosanganisirwa nemishonga yekutora mwando).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• musoro
• dzungu

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune sapropterin.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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