Tolvaptan (yakaderera ropa sodium)

Zvemukati

• Usati watora tolvaptan (Samsca),
• Tolvaptan (Samsca) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Tolvaptan (Samsca) inogona kukonzera iyo mwero wesodium muropa rako kuwedzera nekukurumidza. Izvi zvinogona kukonzera osmotic demyelination syndrome (ODS; kukuvara kwetsinga kwakakomba uko kunogona kukonzerwa nekukasira kuwedzera mumatunhu e sodium). Udza chiremba wako kana ukanwa kana kuti wakambonwa doro rakawanda, kana uine kushaya zvinovaka muviri (muviri unoshaya zvinovaka muviri zvinodiwa kuti uve noutano hwakanaka), uye kana uine kana wakambove nechirwere chechiropa kana yakaderera zvakanyanya sodium muropa rako. .

Iwe nachiremba wako muchatora matanho ekuzvidzivirira kuedza kudzivirira ODS. Iwe unozotanga kurapwa kwako ne tolvaptan (Samsca) muchipatara kuitira kuti chiremba wako akwanise kukutarisa zvakanyanya. Kana chiremba wako akakuudza kuti ramba uchitora tolvaptan (Samsca) mushure mekubva muchipatara, haufanire kumira wotangazve kurapwa wega. Iwe unozofanirwa kudzokera kuchipatara kana iwe uchitangazve mushonga.

Iwe unozofanirwa kunwa mvura pese paunenge uine nyota yekubatsira kudzivirira ODS panguva yekurapa kwako ne tolvaptan (Samsca). Chiremba wako haazopa tolvaptan (Samsca) kana iwe usingakwanise kunzwa kuti une nyota. Iwe unofanirwa kunge uine mvura yekunwa inowanikwa nguva dzese panguva yekurapa kwako.

Kana ukasangana nechimwe chezviratidzo zvinotevera zveODS, udza chiremba wako nekukasira: kunetsekana kutaura, kunetseka kumedza, kunzwa kuti chikafu kana zvinwiwa zviri kunamira muhuro mako, kurara, kuvhiringidzika, kushanduka kwemanzwiro, kufamba kwemuviri kunonetsa kudzora, kushaya simba yemaoko kana makumbo, kana kubatwa.

Iwe unofanirwa kuziva kuti tolvaptan inowanikwawo sehwendefa (Jynarque) kunonoka kuwedzera kwekuita kweitsvo muvanhu vakuru vane imwe mhando yechirwere cheitsvo chakagarwa nhaka. Kana iwe uine chirwere cheitsvo ichi, haufanire kutora tolvaptan (Samsca). Nekuda kwenjodzi yezvinetso zveropa ne tolvaptan, Jynarque inowanikwa chete kuburikidza neyakaganhurirwa chirongwa chekuparadzira. Iyi monograph inopa chete ruzivo nezve tolvaptan mahwendefa (Samsca) kurapa yakaderera masosi e sodium muropa. Kana iwe urikushandisa uyu mushonga kudzora kuwedzera kwekuita kweitsvo yako, verenga iyo monograph yakanzi tolvaptan (chirwere cheitsvo).

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro Rekurapa) paunotanga kurapwa netolvaptan uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi yekutora tolvaptan (Samsca).

Tolvaptan (Samsca) inoshandiswa kurapa hyponatremia (yakaderera masosiamu muropa) mune vanhu vane moyo kukundikana (mamiriro umo moyo usingakwanise kupomba ropa rakakwana kumativi ese emuviri), chirwere cheasina kukodzera antidiuretic hormone (SIADH; mamiriro ekuti muviri unoburitsa zvakawandisa zvechimwe chinhu chehunhu chinokonzeresa kuti muviri uchengete mvura) kana mamwe mamiriro. Tolvaptan iri mukirasi yemishonga inonzi vasopressin V₂ vanopikisa vanogamuchira. Inoshanda nekuwedzera huwandu hwemvura yakaburitswa kubva mumuviri kunge weti. Kubvisa mvura kubva mumuviri kunobatsira kuwedzera mwero we sodium muropa.

Tolvaptan (Samsca) inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva kana kana pasina chikafu kweasingapfuuri mazuva makumi matatu. Pakutanga kwekurapwa kwako, iwe unozopihwa tolvaptan (Samsca) panguva yakajairwa nguva muchipatara. Kana iwe ukaudzwa kutora tolvaptan (Samsca) kumba mushure mekusunungurwa, iwe unofanirwa kuitora panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora tolvaptan (Samsca) chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Chiremba wako angangotanga iwe pane yakaderera dosi ye tolvaptan (Samsca) uye zvishoma nezvishoma wedzera yako dosi, kwete kakawanda kupfuura kamwe chete maawa makumi maviri nemana.

Taura nachiremba wako nezve izvo zvaunofanira kuita mushure mekumira kutora tolvaptan (Samsca). Iwe ungangoda kudzikamisa huwandu hwemvura yaunonwa, uye chiremba wako anozokutarisa nokungwarira panguva ino.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora tolvaptan (Samsca),

• udza chiremba wako uye wemishonga kana uri weergoria kune tolvaptan (Samsca, Jynarque), chero mimwe mishonga, kana chero chinhu chinowanikwa mumatafura etolvaptan. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana iwe uri kutora mamwe maantifungal akadai ketoconazole (Nizoral) kana itraconazole (Sporanox); clarithromycin (Biaxin); mimwe mishonga yeHIV yakadai seininavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), kana saquinavir (Invirase); desmopressin (dDAVP, Yakajeka); nefazodone; kana telithromycin (Ketek). Chiremba wako anogona kukuudza kuti usatore tolvaptan (Samsca) kana uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: angiotensin-inoshandura enzyme (ACE) inhibitors senge benazepril (Lotensin, muLotrel), captopril, enalapril (Vasotec, muVaseretic), fosinopril, lisinopril (Prinivil, Zestril, in Zestoretic), moexipr. , perindopril, (quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), uye trandolapril (Tarka); angiotensin II receptor blockers senge candesartan (Atacand), eprosartan, irbesartan (Avapro, muAvalideza), losartan , muHyzaar), olmesartan (Benicar, muBenicar HCT, muTribenzor), telmisartan (Micardis, muTwynsta), uye valsartan (Diovan, Prexxartan, muEntresto, muEexforge); aprepitant (Emend); barbiturates akadai phenobarbital; carbamazarine (Carbatrol, Equetro, Tegretol); cyclosporine (Gengraf, Neoral, Sandimmune); desmopressin (dDAVP, Minirin, Noctiva), digoxin (Lanoxin); diltiazem (Cardizem, Diltzac, Tiazac); diuretics (mapiritsi emvura); erythromycin ( ERYC, Erythrocin, PCE); fluconazole (Diflucan); phenytoin (Dilant mu); potasiamu zvinowedzera; rifabutin (Mycobutin); rifampin (Rimactane, Rifadin, muRifater, muRifamate); rifapentine (Priftin); uye verapamil (Calan, Verelan, muTarka). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne tolvaptan (Samsca), saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora kana kuronga kutora, kunyanya St John's wort.
• udza chiremba wako kana uine chirwere cheitsvo uye usingaburitse weti, kana uchirutsa zvakanyanya kana kuita manyoka, kana kana warasikirwa nemvura yakawanda kubva mumuviri wako uye uchinzwa dzungu kana kupera simba. Chiremba wako angangokuudza kuti usatore tolvaptan (Samsca). Chiremba wako zvakare anogona kunge asinganyore tolvaptan (Samsca) kana yako sodium chikamu ichifanira kuwedzerwa nekukurumidza zvakanyanya.
• udza chiremba wako kana iwe kana wakambove nehupamhi hwepotasiamu muropa rako.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora tolvaptan (Samsca), fonera chiremba wako.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Tolvaptan (Samsca) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• nyota
• muromo wakaoma
• kazhinji, kuwedzeredza weti
• kuvimbiswa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:

• kurasikirwa nenzara
• kusvotwa
• kurutsa
• kupindwa nechando
• kunzwa kusagadzikana
• kuneta zvisina kujairika kana kushaya simba
• kuvava
• yero yeganda kana maziso
• weti yakasviba
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• manyoka
• kutadza kunwa zvakajairika
• dzungu
• kupera simba
• rutsa rune ropa kana rwunoita kunge kofi nzvimbo
• reropa kana dema uye zvigaro zvekugara
• kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, tsoka, makumbo, kana makumbo ezasi
• hoarseness
• mikoko
• mapundu

Tolvaptan (Samsca) inogona kukonzera mimwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• kunyanyisa kuita weti
• nyota yakanyanyisa
• dzungu
• kupera simba

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira mamwe marabhoritari kuti aongorore mhinduro yemuviri wako kutolvaptan (Samsca).

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Samsca^®