Pazopanib

Zvemukati

• Usati watora pazopanib,
• Pazopanib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

Pazopanib inogona kukonzera kukuvadza kwakanyanya kana kutyisidzira hupenyu. Udza chiremba wako kana iwe wakambove kana wakambove nechirwere chechiropa. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza: yero yeganda kana maziso; weti yakasviba; kuneta kwakanyanya; kusvotwa; kurutsa; kurasikirwa nenzara; kurwadziwa kumusoro kwepamusoro chikamu chedumbu; kana kubuda ropa zvisina kujairika kana kupwanya.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mamwe marabhoritari usati watanga kutora pazopanib uye kanokwana kamwe pamwedzi kwemwedzi mina yekutanga yekurapa kwako uyezve nguva nenguva sezvazvinodiwa.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa nepazopanib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora pazopanib.

Pazopanib inoshandiswa kurapa yakakwira renal cell carcinoma (RCC, rudzi rwekenza inotanga mumasero eitsvo) muvanhu vakuru. Pazopanib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekuderedza kana kumisa kupararira kwekenza masero.

Pazopanib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa isina chinhu mudumbu kamwe pazuva, ingangoita 1 awa pamberi kana maawa maviri mushure mekudya. Tora pazopanib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora pazopanib chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako anogona kugadzirisa yako pazopanib panguva yekurapa kwako kana anogona kurega kurapwa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye chero mhedzisiro iwe yaungasangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora pazopanib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora pazopanib usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora pazopanib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune pazopanib, chero mimwe mishonga, kana chero chinhu chinosanganiswa mumapiritsi epazopanib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: cisapride (Propulsid) (haisipo muU.S.); clarithromycin (Biaxin, muPrevpac); dofetilide (Tikosyn); erythromycin (EES, E-Mycin, Erythrocin); ketoconazole (Nizoral); mimwe mishonga yekushaya moyo zvisina kujairika senge amiodarone (Cordarone), digoxin (Digitek, Lanoxicaps, Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac, vamwe), disopyramide (Norpace), flecainide (Tambocor), mexiletine (Mexitil), procainamide ), propafenone (Rythmol), propranolol (Inderal, Innopran XL, muInderide), quinidine, sotalol (Betapace, Betapace AF, Sorine), uye verapamil (Calan, Isoptin, Verelan); moxifloxacin (Avelox); pimozide (Orap); rifampin (Rifadin, muRifamate, muRifater, Rimactane); ritonavir (Norvir, muKaletra); sparfloxacin (Zagam) (haina kuwanikwa muU.S.); uye thioridazine (Mellaril). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana nepazopanib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana wakosora ropa kana kubuda ropa mudumbu, ura, kana huropi mumwedzi mitanhatu yekupedzisira kana kuvhiyiwa mumazuva manomwe apfuura. Uyezve udza chiremba wako kana iwe kana wakambove nemisodzi mudumbu kana ura; hukama husina kujairika pakati pezvikamu zviviri zvegwara rako remudumbu; Gilbert's syndrome (chiberekero chinokanganisa chiropa uye chinogona kukonzera jaundice [yero yeganda kana maziso]); kukwirira kweropa; sitiroko; kurova kwemoyo zvisina kujairika; nguva yakareba yeQT (chinetso chemoyo chisingawanzo chinogona kukonzera kurova kwemoyo zvisina kujairika, kufenda, kana kufa kamwe kamwe); chirwere chemwoyo; kurwadziwa muchipfuva; kana chirwere chemoyo kana chetachiona.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe haufanire kuve nepamuviri iwe uri kutora pazopanib. Kana iwe ukava nepamuviri uchitora pazopanib, fonera chiremba wako. Pazopanib inogona kukuvadza fetus.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora pazopanib.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri mukati maawa gumi nemaviri eiyo inotevera yako yakarongwa dhizaini, svetuka iyo yakarasika dhizaini uye enderera yako yenguva dzose dosing chirongwa. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Pazopanib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kuvimbiswa
• chirungurira
• chinja mukugona kuravira chikafu
• kubatana kana kurwadziwa kwemhasuru
• kuzvimba kwechiso
• nyoro, matsvuku emichindwe emaoko uye pasi petsoka
• kurasikirwa nevhudzi
• nzara, mutswe, nzara kana bvudzi
• chinja bvudzi bvudzi
• kujekesa kwenzvimbo yeganda
• mapundu
• kushaya simba
• kuora mwoyo
• kujairika kusagadzikana mukutonhora kutonhora
• kuonda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:

• nekukurumidza kana zvisina kujairika kurova kwemoyo
• kurwadziwa pachipfuva
• kurwadziwa mumaoko, musana, mutsipa kana shaya
• mweya wekufema
• musoro
• kutaura kunonoka kana kuoma
• dzungu kana kupera simba
• kushaya simba kana kushama ruoko kana gumbo
• maronda asingarape
• kurwadziwa nemudumbu kana kuzvimba
• nhema uye yekumhara zvituru
• ropa dzvuku muzvituru
• kurutsa kweropa
• rutsa zvinoita kunge kofi nzvimbo
• ropa mune weti
• mhino dzemhino
• kukosora ropa

Pazopanib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• kuneta zvakanyanya

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Votrient^®