Fingolimod
Zvemukati
- Usati watora fingolimod,
- Fingolimod inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
- Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:
- Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:
Fingolimod inoshandiswa kudzivirira zvikamu zvezviratidzo uye kunonoka kuwedzera kwekuremara kwevakuru uye vana vane makore gumi ekuberekwa nekure nekudzokazve-kudzosera mafomu (kosi yechirwere uko zviratidzo zvinopisa nguva nenguva) ye multiple sclerosis (MS; chirwere umo tsinga dzisingashande nemazvo uye vanhu vanogona kusangana neutera, chiveve, kurasikirwa kwekufambirana kwemhasuru, uye matambudziko nekuona, kutaura, uye kudzora kwedundira). Fingolimod iri mukirasi yemishonga inonzi sphingosine l-phosphate receptor modulators. Inoshanda nekudzora kuita kwema immune maseru anogona kukonzera kukuvara kwetsinga.
Fingolimod inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva kana pasina chikafu. Tora fingolimod panguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora fingolimod chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.
Fingolimod inogona kukonzera kurova kwemoyo kunonoka muvakuru nevana, kunyanya panguva yekutanga kwemaawa matanhatu mushure mekutora yako yekutanga dhizeti, uye mushure mekutanga dosi kana iro dosi riwedzerwa muvana. Iwe unozogashira iyo electrocardiogram (ECG; bvunzo iyo inorekodha mashandiro emagetsi emoyo) usati watora yako yekutanga dhizeti uye zvakare maawa matanhatu mushure mekutora iwo muyero. Iwe unotora yako yekutanga dosi yefingolimod muhofisi yako yechiremba kana imwe nzvimbo yekurapa. Iwe unozofanirwa kugara kunzvimbo yekurapa kweinenge maawa matanhatu mushure mekunwa mushonga kuti ugone kuongororwa. Iwe ungangoda kugara kunzvimbo yekurapa kwenguva yakareba kupfuura maawa matanhatu kana husiku husiku kana uine mamwe mamiriro kana kutora mimwe mishonga inowedzera njodzi yekuti kurova kwemoyo wako kunonoka kana kana kurova kwemoyo wako kuchinonoka kupfuura zvaitarisirwa kana kuramba uchinonoka mushure mekutanga 6 maawa. Iwe unogona zvakare kuda kugara kuchipatara kweanenge maawa matanhatu mushure mekutora yako yechipiri dosi kana kurova kwemoyo wako kuchinonoka zvakanyanya kana iwe uchitora yako yekutanga dosi. Udza chiremba wako kana iwe uchinge uchinzwa dzungu, kuneta, kurwadziwa pachipfuva, kana kunonoka kana kusagadzikana kwemoyo chero nguva panguva yekurapwa kwako, kunyanya panguva yekutanga maawa makumi maviri nemaviri mushure mekutora yako yekutanga dosi.
Fingolimod inogona kubatsira kudzora multiple sclerosis asi haizorape. Usarega kutora fingolimod usina kutaura nachiremba wako. Kana iwe usingatore fingolimod kwezuva rimwe kana kupfuura mukati memavhiki maviri ekutanga ekurapwa, kwevhiki rimwe chete kana kupfuura muvhiki yechitatu neyechina yekurapwa kana kwemavhiki maviri kana kupfuura mushure memwedzi wekutanga wekurapa, taura nachiremba wako usati unotanga kuitora zvakare. Unogona kusangana nemoyo unononoka kurova paunotanga kutora fingolimod zvakare, saka unozotangazve mishonga muhofisi yechiremba wako.
Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne fingolimod uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.
Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.
Usati watora fingolimod,
- udza chiremba wako uye wemishonga kana iwe uri weergoria kune fingolimod, Kana iwe wakambove neakanyanya kukanganiswa nemagetsi kune fingolimod kana chero chinhu chinosanganiswa mune fingolimod capsules (mapundu, mikoko, kuzvimba kwechiso, maziso, muromo, huro, rurimi, miromo, maoko, tsoka, makumbo, kana makumbo ezasi), chiremba wako angangodaro uudze kwete fingolimod. Zvakare, udza chiremba wako kana uri weergoria kune chero mimwe mishonga, kana chero chimwe chezvinhu zviri mu fingolimod capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
- udza chiremba wako kana uri kutora mishonga yekusagadzikana kwemoyo kwakadai saamiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), ibutilide (Corvert), procainamide, quinidine (muNuedexta), uye sotalolide (Betapace, Sorine, Sotylize). Chiremba wako angangokuudza kuti usatore fingolimod kana uri kutora imwe kana yakawanda yemishonga iyi.
- udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera zvinovaka muviri, uye zvigadzirwa zvemakwenzi zvauri kutora kana kuronga kutora panguva yekurapwa kwako ne fingolimod. Ive neshuwa yekutaura chero eanotevera: beta-blockers senge atenolol (Tenormin, muTenoretic), carteolol, labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, muDutoprol, muLopressor HCT), nadolol (Corgard, mu Corzide), nebivolol (Bystolic, muByvalson), propranolol (Inderal LA, Innopran XL), uye timolol; diltiazem (Cardizem, Cartia, Tiazac, nevamwe); chlorpromazine; citalopram (Celexa); digoxin (Lanoxin); erythromycin (EES, Ery-Tab, PCE, nevamwe); haloperidol (Haldol); ketoconazole; mishonga yematambudziko emwoyo; methadone (Dolophine, Methadose); uye verapamil (Calan, Verelan, muTarka).Zvakare kukuudza iwe chiremba kana uri kutora chero anotevera emishonga, kana kana iwe wakambonwa kare: corticosteroids senge dexamethasone, methylprednisolone, uye prednisone; mishonga yekenza; uye mishonga yekunetesa kana kudzora immune system yakadai semitoxantrone, natalizumab (Tysabri), uye teriflunomide (Aubagio), Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne fingolimod, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
- udza chiremba wako kana iwe wakambove kana nechero cheaya mamiriro mumwedzi mitanhatu yapfuura: chirwere chemwoyo, angina (kurwadziwa pachipfuva), sitiroko kana mini-stroke, kana kukundikana kwemoyo. Uyezve udza chiremba wako kana iwe uine refu QT syndrome (mamiriro anowedzera mukana wekuvandudza kurovera kusingaite kwemoyo kunogona kukonzera kupera simba kana kufa kamwe kamwe) kana zvisina kujairika moyo mutinhimira. Chiremba wako anogona kukuudza kuti usatore fingolimod.
- udza chiremba wako kana wakambofenda, wakarwadziwa nemoyo, kurohwa, kana kurohwa zvishoma, kana kana uine fever kana zvimwe zviratidzo zvehutachiona, kana uine hutachiona hunouya nekuenda kana husingaendi, uye kana iwe kana wakambove nechirwere cheshuga; kurara kufema (mamiriro umo iwe unomira kwenguva pfupi kufema kazhinji mukati mehusiku) kana zvimwe zvinetso zvekufema; kukwirira kweropa; uveitis (kuzvimba kweziso) kana mamwe matambudziko eziso; kurova kwemoyo kunononoka; yakaderera masosi e potassium kana magnesium muropa rako; gomarara reganda, kana chirwere chemoyo kana chechiropa. Uyezve udza chiremba wako kana uchangobva kugamuchira mushonga.
- udza chiremba wako kana iwe uri nepamuviri kana kuronga kuva nepamuviri, kana uri kuyamwisa. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako uye kwemwedzi miviri mushure mekupedzisira kwako dose. Kana iwe ukava nepamuviri uchitora fingolimod kana mukati memwedzi miviri mushure mekupedzisira kwako, daidza chiremba wako.
- hauna majekiseni panguva yekurapa kwako ne fingolimod kana kwemwedzi miviri mushure mekuita kwako kwekupedzisira usingataure nachiremba wako. Taura nachiremba wemwana wako nezve majekiseni ayo mwana wako angangoda kugamuchira asati atanga kurapwa kwake ne fingolimod.
- udza chiremba wako kana usati wambobata chepfu uye usati wawana mushonga wekurapa. Chiremba wako anogona kuraira kuongororwa kweropa kuti aone kana iwe wakambosangana nehuku hwehuku. Ungangoda kugamuchira mushonga wekurwara wehuku wozomirira mwedzi mumwe usati watanga kurapwa kwako ne fingolimod.
- ronga kudzivirira kudzivirirwa zvisina kufanira kana kwenguva refu kune mwenje wezuva uye mwenje we UV (senge matumba ekuchenesa) uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen. Fingolimod inogona kuita kuti ganda rako rinyatso kunetseka nezviitiko zvinokuvadza zvechiedza chezuva, uye rinogona kuwedzera njodzi yako yekuva nekenza yeganda.
Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.
Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yave nguva yenguva inotevera, svetuka chirwere chakarasika uye danaidza chiremba wako usati watora chirwere chinotevera. Iwe ungangoda kuongororwa sezvo iwe uchitangazve yako mushonga. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.
Fingolimod inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
- kushaya simba
- kurwadziwa shure
- kurwadziwa mumaoko kana tsoka
- manyoka
- marwadzo emudumbu
- kusvotwa
- musoro kana migraine
- kurasikirwa nevhudzi
Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:
- kunonoka kurova kwemoyo
- mapundu, mikoko, kuvaviwa; kuzvimba kwechiso, ziso, muromo, huro, rurimi kana miromo; kana kunetseka kumedza kana kufema
- kurwadziwa pahuro, kurwadziwa nemuviri, kupisa muviri, kutonhora, kukosora, uye zvimwe zviratidzo zvehutachiona uye panguva yekurapwa uye kwemwedzi miviri mushure mekurapwa kwako.
- kutemwa nemusoro, kuomarara kwemutsipa, kupisa muviri, kunzwisisika kuchiedza, kuda kurutsa, kana kuvhiringidzika panguva yekurapwa uye kwemwedzi miviri mushure mekurapwa kwako
- kunorwadza, kutsva, kupera simba, kana kugunzwa kunzwa paganda, kunzwisisika kwekubata, kuputika, kana kuchenesa panguva yekurapwa uye kwemwedzi miviri mushure mekurapwa kwako
- kamwe kamwe kwakakomba musoro, kuvhiringidzika, shanduko muchiono, kana kubatwa
- kusvibiswa, mimvuri, kana bofu nzvimbo pakati pechiratidzo chako; kunzwisisika kuchiedza; isina kujairika ruvara kune chiono chako kana mamwe matambudziko ekuona
- shanduko kune mole iripo; nzvimbo nyowani yakasviba paganda; maronda asingapore; kukura paganda rako senge bundu rinogona kupenya, rakacheneruka chena, rine ruvara rweganda, kana pingi, kana chero shanduko paganda rako
- kushaya simba kune rumwe rutivi rwemuviri kana kusindimara kwemaoko kana makumbo izvo zvinowedzera kuwedzera nekufamba kwenguva; shanduko mukufunga kwako, ndangariro, kana kuenzanisa; kuvhiringidzika kana kuchinja hunhu; kana kupera simba
- nyowani kana kuwedzera kupfupika kwekufema
- kusvotwa, kurutsa, kurasikirwa nehavi, kurwadziwa mudumbu, kuita yero kweganda kana maziso, kana weti yakasviba
Fingolimod inogona kuwedzera njodzi yekuva nekenza yeganda uye lymphoma (kenza inotanga mumasero anorwisa hutachiona). Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.
Kuwedzera kamwe kamwe kwezvikamu zveMS zviratidzo uye kuwedzera kwekuremara kunogona kuitika mukati memwedzi mitatu kusvika kumatanhatu mushure mekumira kutora fingolimod. Udza chiremba wako kana zviratidzo zvako zveMS zvinowedzera mushure mekumisa fingolimod.
Fingolimod inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.
Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).
Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).
Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org
Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.
Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.
Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:
- kunonoka kana kusagadzikana kwemoyo
Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira kumwe kuongorora kwelebhu, uye bvunzo dzeganda uye dzemaziso, uye anozotarisa kuwedzerwa kweropa rako usati uye panguva yekurapwa kwako kuti uve nechokwadi chekuti zvakachengeteka kwauri kuti utange kutora kana kuramba uchitora fingolimod.
Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti uri kutora fingolimod
Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.
Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.
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