Ipilimumab Jekiseni

Zvemukati

• Usati wagamuchira ipilimumab jekiseni,
• Ipilimumab inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira.

Ipilimumab jekiseni rinoshandiswa:

• kurapa melanoma (rudzi rwegomarara reganda) muvakuru nevana vane makore gumi nemaviri zvichikwira isingakwanise kurapwa nekuvhiyiwa kana yakapararira kune dzimwe nhengo dzemuviri.
• kubatsira kudzivirira melanoma kubva mukudzoka mushure mekuvhiyiwa kuti ibvise iyo uye chero anokanganisa lymph node.
• pamwe chete nivolumab (Opdivo) kurapa yakakwira renal cell carcinoma (RCC; mhando yekenza inotanga mumasero eitsvo).
• pamwe chete nivolumab kurapa mamwe marudzi ecolorectal cancer (kenza inotanga mumatumbo mahombe) muvanhu vakuru uye vana vane makore gumi nemaviri ekuberekwa uye yakapararira kune mamwe mativi emuviri uye yawedzera mushure mekurapwa nemamwe mishonga yekemotherapy.
• pamwe chete nivolumab kurapa hepatocellular carcinoma (HCC; rudzi rwegomarara rechiropa) muvanhu vakamborapwa ne sorafenib (Nexafar).
• pamwe chete nivolumab kune imwe mhando yekenza yemapapu (isiri-diki kenza yemapapu kenza; NSCLC) kune vakuru yakapararira kune mamwe mativi emuviri.
• mukubatana nivolumab uye platinum chemotherapy yekurapa imwe mhando yeNSCLC muvakuru yakadzoka kana yakapararira kune dzimwe nhengo dzomuviri.
• mukubatana nivolumab kurapa zvakaipa malthelioma mesothelioma (mhando yekenza inobata mukati memukati memapapu uye chipfuva) mune vanhu vakuru vasingakwanise kubviswa nekuvhiya.

Ipilimumab jekiseni iri mukirasi yemishonga inonzi monoclonal antibodies. Inoshanda nekubatsira muviri kudzora kana kumisa kukura kwemasero ekenza.

Ipilimumab jekiseni inouya semhinduro (mvura) kujowa mukati (mutsinga) nachiremba kana mukoti muchipatara kana nzvimbo yekurapa. Kana ipilimumab ikapihwa kurapa melanoma, inowanzo kupihwa pamusoro pemaminetsi makumi mapfumbamwe kamwe chete pavhiki nhatu chero bedzi chiremba wako achikurudzira kuti ugamuchire kurapwa. Kana ipilimumab ikapihwa nivolumab kurapa renal cell carcinoma, hepatocellular carcinoma, kana colorectal cancer, inowanzo kupihwa inopfuura maminetsi makumi matatu kamwe chete pavhiki nhatu kusvika kumitezo mina. Kana ipilimumab ikapihwa nivolumab kana nivolumab uye platinum chemotherapy yekurapa NSCLC, inowanzo kupihwa pamusoro pemaminetsi makumi matatu kamwe chete pavhiki nhanhatu chero bedzi chiremba wako achikurudzira kuti uwane kurapwa. Kana ipilimumab ikapihwa nivolumab yekurapa yakaipa malathelioma mesothelioma, inowanzo kupihwa pamusoro pemaminetsi makumi matatu kamwechete kwevhiki nhanhatu chero bedzi chiremba wako achikurudzira kuti ugamuchire kurapwa.

Ipilimumab jekiseni inogona kukonzera zvakakomba kana kutyisidzira hupenyu panguva yekumukirwa. Chiremba kana mukoti anozokutarisa zvakanyanya paunenge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge Udza chiremba wako kana mukoti nekukasira kana iwe uchinge wawana chero cheanotevera zviratidzo anogona kuitika panguva yekunyudzwa

Chiremba wako anogona kudzora infusion yako, kunonoka, kana kumisa kurapwa kwako neipilimumab jekiseni, kana kukubata iwe nemimwe mishonga zvichienderana nemhinduro yako kumushonga uye chero mhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa neipilimumab uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira ipilimumab jekiseni,

• udza chiremba wako uye wemishonga kana uri weergoria kune ipilimumab jekiseni, chero mimwe mishonga, kana chero chinhu chinosanganiswa muipilimumab jekiseni. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove nekuiswa nhengo, chirwere chechiropa, kana kana chiropa chako chakakuvara nemushonga kana chirwere. Zvakare, udza chiremba wako kana iwe kana wakambove nechirwere chekuzvidzivirira muviri (mamiriro umo immune system inorwisa chikamu chine hutano chemuviri) senge chirwere cheCrohn (mamiriro umo immune system inorwisa iyo lining yeiyo yekugaya nzira inokonzera kurwadziwa , manyoka, kuonda, nefivhiri), ulcerative colitis (chirwere chinokonzeresa kuzvimba nemaronda mumucheto wekoloni [ura hukuru] nerekure), lupus (mamiriro umo immune system inorwisa matishu mazhinji uye nhengo kusanganisira ganda, majoini, ropa, neitsvo), kana sarcoidosis (mamiriro umo makomba emasero asina kujairika anokura munzvimbo dzakasiyana dzemuviri kusanganisira mapapu, ganda, uye maziso).
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kutora nhumbu yekubata usati wagamuchira ipilimumab. Iwe unofanirwa kushandisa inoshanda yekudzivirira kudzivirira kubata pamuviri panguva yekurapa kwako neipilimumab jekiseni uye kwemwedzi mitatu mushure mekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri iwe uchigamuchira ipilimumab jekiseni, dana chiremba wako nekukasira. Ipilimumab jekiseni inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchigamuchira ipilimumab jekiseni uye kwemwedzi mitatu mushure mekupedzisira kwedosi.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Ipilimumab inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kunetseka kurara kana kuramba wakarara
• kurwadza kwemajoini

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira.

• kudzikira kwekuita weti, ropa mumurini, kuzvimba kwetsoka, makumbo, kana makumbo ezasi, kana kurasikirwa nechido
• manyoka, ane ropa kana dema, mira, zvituru zvinonamira, kurwadziwa zvakanyanya mudumbu kana unyoro, kana fivha
• kukosora, kurwadziwa pachipfuva, kana kufema kwekufema
• kuneta, kuvhiringidzika, matambudziko ekurangarira, kuona zvisipo, kugwinha, kana mutsipa wakaomarara
• kunzwa kuneta, kuwedzera kudya, kuwedzera nyota, kuwedzera kuita weti, kana kuonda
• kukurumidza kurova kwemoyo, kuzunza kusingadzoreki kwechikamu chemuviri, kuwedzerwa kuda kudya, kana kudikitira
• kuneta kana usimbe, kuwedzera kunzwisiswa nechando, kuvhiringidzika, kurwadziwa nemhasuru uye kushaya simba, kuwedzera huremu, zvinorema kupfuura zvakajairwa kana zvisina kujairika kumwedzi, kutetepa bvudzi, kutemwa nemusoro, dzungu, kusagadzikana, kukanganwa, kuderera kwekutyaira pabonde, kana kushushikana
• yero yeganda kana maziso, rima (tii-rakatsvuka) weti, kurwadziwa kumusoro kwekurudyi chikamu chedumbu, kuda kurutsa, kurutsa, kana kupwanya kuri nyore kana kubuda ropa.
• kushaya simba kunoshamisa kwemakumbo, maoko, kana kumeso; kana kudzikama kana kugwinha maoko kana tsoka
• kumhanyisa pamwe kana pasina kuchenesa, kuputika kana kubvisa ganda, kana maronda emuromo
• kusaona zvakanaka, kuona kaviri, kurwadziwa kweziso kana kutsvuka, kana mamwe matambudziko ekuona

Ipilimumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika iwe uchinge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve ipilimumab jekiseni.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira zvimwe bvunzo usati uye panguva yekurapa kwako kuti uone kana zvakachengeteka kuti iwe ugamuchire ipilimumab jekiseni uye kutarisa mhinduro yemuviri wako kune ipilimumab jekiseni.

Kune mamwe mamiriro, chiremba wako anozoraira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa neipilimumab.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve ipilimumab jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Yervoy^®