Ruxolitinib

Zvemukati

• Usati watora ruxolitinib,
• Ruxolitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Ruxolitinib inoshandiswa kurapa myelofibrosis (kenza yemongo wemapfupa umo mwongo wepfupa unotsiviwa nemavanga uye inokonzeresa kugadzirwa kwemasero eropa). Iyo inoshandiswawo kurapa polycythemia vera (PV; kenza inononoka kukura yeropa umo mwongo wemapfupa unoita masero matsvuku eropa akawandisa) muvanhu vasina kukwanisa kurapwa zvinobudirira nehydroxyurea. Ruxolitinib inoshandiswawo kurapa kubatanidza maringe nehutachiona hwehutachiona (GVHD; chinetso chehematopoietic stem-cell transplant [HSCT; maitiro anotsiva marora emapfupa ane mwongo wemapfupa ane hutano]) muvanhu vakuru uye vana vane makore gumi nemaviri ekuberekwa uye vakuru vairapwa. zvisina kubudirira nemishonga ye steroid. Ruxolitinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda kurapa myelofibrosis uye PV nekudzivirira zviratidzo zvinokonzeresa kuti maseru ekenza awande. Izvi zvinobatsira kumisa kupararira kwemasero ekenza. Inoshanda kurapa GVHD nekuvharira iwo maseru emaseru anokonzeresa GVHD.

Ruxolitinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva. Tora ruxolitinib panguva dzakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ruxolitinib chaizvo sekurairwa. Usatore zvimwe kana zvishoma zvacho, kana kuitora kakawanda kupfuura zvakatemwa nachiremba wako.

Kana iwe uri kurapwa for myelofibrosis kana PV chiremba wako anogona kukutanga iwe pane yakaderera dosi reruxolitinib kwemavhiki mana ekutanga ekurapwa, uye zvishoma nezvishoma wedzera dosi rako mushure menguva iyoyo, kwete kanopfuura kamwe chete pavhiki mbiri Kana iwe uri kurapwa GVHD chiremba wako anogona kukutanga iwe pane yakaderera dosi reruxolitinib uye inogona kuwedzera yako dosi mushure memazuva mashoma matatu ekurapwa.

Medza mapiritsi akazara; usatsvage kana kuapwanya.

Kana iwe usingakwanise kuwana chikafu nemuromo uye uine nasogastric (NG) chubhu, chiremba wako anogona kukuudza iwe kuti utore ruxolitinib kuburikidza nasogastric (NG) chubhu. Chiremba wako kana wemishonga anotsanangura kuti ungagadzirira sei ruxolitinib yekupa kuburikidza neNG tube.

Chiremba wako acharaira kuongororwa kweropa usati uye panguva yekurapa kwako kuti uone kuti unokanganiswa sei nemushonga uyu. Chiremba wako anogona kuwedzera kana kudzikisa dosi rako reruxolitinib panguva yekurapa kwako, kana anogona kukuudza kuti umise kutora ruxolitinib kwechinguva. Izvi zvinoenderana nekuti mushonga unoshanda zvakadii kwauri, zviongororwa zvebazi rako, uye kana iwe ukava nemhedzisiro. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora ruxolitinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora ruxolitinib usina kutaura nachiremba wako. Kana chiremba wako akafunga kumisa kurapa kwako ne ruxolitinib, chiremba wako anogona kudzora dosi rako zvishoma nezvishoma.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora ruxolitinib,

• udza chiremba wako uye wemishonga kana uri weergoria kune ruxolitinib, chero mimwe mishonga, kana chero chipi chinosanganiswa mu ruxolitinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antifungal mishonga inosanganisira itraconazole (Sporanox), ketoconazole, uye voriconazole (Vfend); carbamazepine (Carbatrol, Equetro, Tegretol, vamwe); clarithromycin; efavirenz (Sustiva, muAtripla, Symfi); fluconazole (Diflucan); HIV protease inhibitors inosanganisira indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, muKaletra, Viekira Pak), uye saquinavir (Invirase); mibefradil (Posicor); nefazodone; nevirapine (Viramune); phenytoin (Dilantin, Phenytek); pioglitazone (Actos, muOseni, Duetact); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, Rifater); telaprevir (Incivik); uye telithromycin (Ketek). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.Mimwe mishonga yakawanda inogona zvakare kubatana neruxolitinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana uine chirwere chekushaya ropa, hutachiona, kana uri pane dialysis, kana kuti kana iwe nguva pfupi yadarika wakakomberedza mumwe munhu ane tibhii (TB, chirwere chakakomba chemapapu) kana kushanyira kana kugara kunowanikwa TB. Uyezve udza chiremba wako kana iwe kana wakambove uine TB, cholesterol yakawanda, gomarara reganda, hepatitis B kana chimwe chirwere chechiropa, kana chirwere cheitsvo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora ruxolitinib, fonera chiremba wako. Iwe haufanire kunwisa mwana uchitora ruxolitinib uye kwemavhiki maviri mushure mekupedzisira kwako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ruxolitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• dzungu
• musoro
• kuneta
• kushaya simba
• mweya wekufema
• kurema kuwedzera
• gasi
• marwadzo emudumbu
• manyoka
• kuvimbiswa
• kusvotwa
• kuvava
• mapundu
• mhasuru kana kurwadziwa kwemajoini
• kuzvimba kwemaoko, makumbo kana zvimwe zvikamu zvemuviri

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• kubuda zvisina kujairika kana kunorema kubuda ropa kana kupwanya
• fivha, kurwadziwa pahuro, kutonhora, kukosora, kurwadziwa pachipfuva, kudikitira usiku, kugara uchirwadza, kuita weti nekukurumidza, uye zvimwe zviratidzo zvehutachiona.
• kupisa, kurira, kuchenesa, kana kunzwisisika kweganda kune rimwe divi remuviri kana kumeso nekupwanya kunorwadza kana mablister anoonekwa mazuva akati wandei gare gare.
• maronda matsva, mapundu, kana kupunduka kana kumwe kuchinja paganda
• ganda rakachenuruka, kuneta, kana kufema kwekufema (kunyanya panguva yekudzidzira)
• kunetsekana kufamba kana kuchengeta muyero, kushaya simba kwemakumbo kana maoko zvinoramba zvichitowedzera, kunetseka kunzwisisa kana kutaura, kurasikirwa ndangariro, matambudziko ekuona, kana shanduko muhunhu

Ruxolitinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• kubuda ropa zvisina kujairika kana kupwanya
• dzungu
• musoro
• kuneta
• fivha, huro, chironda, chikosoro, uye zvimwe zviratidzo zvehutachiona

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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