Vemurafenib

Zvemukati

• Usati watora vemurafenib,
• Vemurafenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:
• Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge

Vemurafenib inoshandiswa kurapa mamwe marudzi e melanoma (rudzi rwegomarara reganda) risingakwanise kurapwa nekuvhiya kana rakapararira kune dzimwe nhengo dzemuviri. Iyo inoshandiswa zvakare kurapa imwe mhando yechirwere cheErdheim-Chester (ECD; chirwere chinokonzera kuwedzeredza kwerudzi rwemasero machena eropa). Vemurafenib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Vemurafenib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva, mangwanani nemanheru, anenge maawa gumi nemaviri akaparadzana. Tora vemurafenib kwakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora vemurafenib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako. Usarega kutora vemurafenib usina kutaura nachiremba wako.

Medza mapiritsi akazara negirazi remvura; usatsvage kana kuapwanya.

Kana ukarutsa mushure mekutora vemurafenib, usakurumidza kutora imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako angangoda kumbomira kurapwa kwenguva pfupi kana zvachose kana kudzikisira muyero wako wemurafenib panguva yekurapwa kwako zvinoenderana nekuti mushonga unoshanda sei kwauri iwe pamwe nemhedzisiro yaunosangana nayo. Ive neshuwa yekuudza chiremba wako kuti unonzwa sei panguva yekurapa kwako vemurafenib.

Chiremba wako kana wemishonga achakupa gwaro reruzivo rwevarwere remugadziri (Gwaro reMishonga) paunotanga kurapwa neemurafenib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora vemurafenib,

• udza chiremba wako uye wemishonga kana uri weergoria kune vemurafenib, chero mimwe mishonga, kana chimwe chezvinhu zviri mumapiritsi ememurafenib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantifungal akadai itraconazole (Onmel, Sporanox), ketoconazole (Nizoral) uye voriconazole (Vfend) clarithromycin (Biaxin, muPrevPac); mimwe mishonga yehutachiona hwehutachiona hwehutachiona hweHIV (HIV) kana yakawana immunodeficiency syndrome (AIDS) senge indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, muCaletra), uye saquinavir (Invirase); mimwe mishonga yekubatwa kwakadai se carbamazepine (Carbatrol, Epitol, Tegretol, vamwe), phenobarbital, uye phenytoin (Dilantin, Phenytek); nefazodone; rifampin (Rifadin, Rimactane, muRifamate, muRifater); tizanidine; uye warfarin (Coumadin, Jantoven). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kupindirana neyemurafenib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
• udza chiremba wako kana iwe wakambove kana wakambove nemhando ipi neipi yekenza yeganda; nguva yakareba yeQT (chinetso chemoyo chisingawanzo chinogona kukonzera kurova kwemoyo zvisina kujairika, kufenda, kana kufa kamwe kamwe); kutadza kwemoyo; yakaderera mwero wecalcium, magnesium, kana potasium muropa rako; mwoyo, itsvo, kana chirwere chechiropa. Uyezve, udza chiremba wako kana iwe wakambove kana uri kuronga kugamuchira radiation radiation.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe haufanire kuve nepamuviri iwe uri kutora vemurafenib. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako nememurafenib uye kwemavhiki maviri mushure mekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora vemurafenib, fonera chiremba wako. Vemurafenib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwa uchi tora vemurafenib uye kwemasvondo maviri mushure mekupedzisira kwako.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora vemurafenib.
• ronga kudzivirira kudzivirirwa zvisina kufanira kana kwenguva refu muchiedza chezuva uye kupfeka mbatya dzekudzivirira, magirazi ezuva, balm yemuromo uye sunscreen (SPF 30 kana kumusoro). Vemurafenib inogona kuita kuti ganda rako ribate chiedza chezuva.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana iri mukati maawa mana emutero wako unotevera wakarongwa, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Vemurafenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuneta
• kubatana, mhasuru, ruoko, gumbo, kana kurwadziwa musana
• kutsvuka kana kuzvimba mumaoko, tsoka, makumbo, kana makumbo ezasi
• chinja mupfungwa yekuravira
• musoro
• kurasikirwa nevhudzi
• ganda rakaoma kana rinonhuwa
• manyoka
• kuvimbiswa
• kukosora

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• shanduko pakuonekwa kweganda
• nyowani nyowani
• ganda rinorwadza kana tsvuku bundu rinobuda ropa kana risingapore
• chinja saizi kana ruvara rwema mole
• kuneta zvakanyanya
• kupwanya kusingawanzo kana kubuda ropa
• kusvotwa
• kurutsa
• kurasikirwa nenzara
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• yero yeganda kana maziso
• ziso kunzwisisika kuchiedza
• kutsvuka kweziso kana kurwadziwa
• maonero anochinja
• kujairika kusimba kwemichindwe emaoko
• kuomesa kweminwe mukati kwakanangana nechanza
• kujairika kusinganzwisisike kwetsoka, izvo zvinogona kurwadza

Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge

• kunetseka kufema kana kumedza
• kukurumidza, kusajairika, kana kurova kwehana
• kufenda
• mapundu kana kutsvuka muviri wese
• mikoko
• kubvarura kana kubvarura ganda
• kupindwa nechando

Vemurafenib inogona kuwedzera njodzi yekuti iwe unogadzira imwe kanzira. Taura nachiremba wako nezve njodzi iyi.

Vemurafenib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti atarise mhinduro yemuviri wako vemurafenib. Chiremba wako anoongorora ganda rako usati watanga kurapwa, mwedzi miviri miviri panguva yekurapwa kwako, uye kusvika kumwedzi mitanhatu mushure mekurapwa.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Zelboraf^®