Mifepristone (Korlym)

Zvemukati

• Usati watora mifepristone,
• Mifepristone inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Kune varwere vechikadzi:

Usatore mifepristone kana iwe uri nepamuviri kana kuronga kuve nepamuviri. Mifepristone inogona kukonzera kurasikirwa kwepamuviri. Iwe unofanirwa kuve nemimba isina nhumbu bvunzo usati watanga kurapwa ne mifepristone uye usati watanga kurapwa zvakare kana ukarega kuitora kweanopfuura mazuva gumi nemana. Kana iwe uchikwanisa kuve nepamuviri, iwe unofanirwa kudzivirira kudzivirira kuva nepamuviri panguva yekurapa kwako ne mifepristone. Iwe unofanirwa kushandisa maitiro anogamuchirwa ekudzivirira kuberekwa panguva yekurapa kwako uye kweinenge mwedzi mumwe mushure mekurapwa kwako kwapera Chiremba wako anokuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinogamuchirwa. Kana iwe uchifunga kuti uri nepamuviri, unosuwa kuenda kumwedzi, kana iwe uchiita bonde pasina kushandisa kuberekwa paunenge uchitora mifepristone kana mukati memwedzi mumwe mushure mekurapwa kwako, danaidza chiremba wako nekukasira.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira mimwe bvunzo kuti utarise mhinduro yemuviri wako kune mifepristone.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne mifepristone uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi (s) yekutora mifepristone.

Mifepristone (Korlym) inoshandiswa kurapa hyperglycemia (shuga yakakwira muropa) muvanhu vane imwe mhando yeCushing's syndrome umo muviri unoita cortisol yakawandisa (hormone) uye vakatadza kuvhiyiwa kana vasingakwanise kuvhiyiwa kuti varape chirwere ichi. Mifepristone iri mukirasi yemishonga inonzi cortisol receptor blockers. Inoshanda nekudzivirira chiitiko checortisol.

Mifepristone inowanikwawo seimwe chigadzirwa (Mifeprex) iyo inoshandiswa yoga kana musanganiswa nemimwe mishonga kupedza nhumbu yekutanga. Iyi monograph inopa chete ruzivo nezve mifepristone (Korlym) inoshandiswa kudzora hyperglycemia mune vanhu vane imwe mhando yeCushing's syndrome. Kana iwe uri kushandisa mifepristone kugumisa nhumbu, verenga monograph yakanzi mifepristone (Mifeprex), iyo yakanyorwa nezve ichi chigadzirwa.

Mifepristone inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva nekudya. Tora mifepristone panenge panguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora mifepristone chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya. Udza chiremba wako kana wemishonga kana iwe usingakwanise kumedza mapiritsi akazara.

Chiremba wako anozokutangira pane yakaderera dosi yemafepristone uye zvishoma nezvishoma wedzera yako dosi, kwete kazhinji kanopfuura kamwe chete kwevhiki mbiri kusvika ina. Kana iwe ukarega kutora mifepristone, fonera chiremba wako. Chiremba wako anogona kutanga iwe zvakare pane yakaderera dosi ye mifepristone uye zvishoma nezvishoma wedzera yako dose.

Mifepristone inogona kudzora mamiriro ako asi isingarape. Zvinogona kutora mavhiki matanhatu kana kupfuura usati wanzwa kuzara kwemafepristone. Ramba uchitora mifepristone kunyangwe iwe uchinzwa zvakanaka.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora mifepristone,

• udza chiremba wako kana uri weergoria kune mifepristone, chero mimwe mishonga, kana chero chinhu chinowanikwa mumafiritsi epepepristone. Kumbira mushonga wako wemishonga kana kutarisa ruzivo rwemurwere wemugadziri kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana uri kutora ipi yemishonga inotevera kana kuti wakanwa mumavhiki maviri apfuura: corticosteroids senge betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, vamwe) , fludrocortisone (Floriner), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, vamwe), prednisolone (Prelone, vamwe), prednisone (Deltasone, Meticorten, Sterapred, vamwe), uye triamcinolone (Aristocort, Azmacort) mishonga inodzvinyirira immune system se cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), uye tacrolimus (Prograf); dihydroergotamine (DHHE 45, Migranal); ergotamine (Ergomar, muCafergot, muMigergot); fentanyl (Duragesic); lovastatin (Mevacor); pimozide (Orap); quinidine (Quinidex); uye simvastatin (Zocor). Chiremba wako angangokuudza kuti usatore mifepristone kana uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzerwa nezvehutano, uye mishonga yemakwenzi yauri kutora kana yawakatora mumavhiki maviri apfuura. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin); antifungals senge itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), kana voriconazole (Vfend); asipurini uye mamwe asiri -steroidal anti-anogumbura zvinodhaka (NSAIDs) senge ibuprofen (Advil, Motrin) uye naproxen (Aleve, Naprosyn); bupropion (Wellbutrin); ciprofloxacin (Cipro); clarithromycin (Biaxin); conivaptan (Vaprisol); diltiazem (Cardizem); erythromycin (EES, E-Mycin, Erythrocin); fluvastatin (Lescol); mishonga yekudzivirira mhuri semapiritsi ekudzivirira kubata pamuviri, zvigamba, zvigamba, mhete, kana majekiseni; mishonga yehepatitis C yakadai seboceprevir (Victrelis) uye telaprevir (Incivek); mishonga yeHIV kana AIDS yakadai seamprenavir (Agenerase), atazanavir (Reyataz), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir uye ritonavir mubatanidzwa (Kaletra), nelfinavir (Viracept), ritonavir (Norvir) uye saquinavir (Fortovase, Invirase); mishonga yekubatwa kwakadai sa carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin); mishonga yetibhii yakaita rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, muRifamate, muRifater) uye rifapentine (Priftin); nefazodone (Serzone); repaglinide (Prandin); telithromycin (Ketek); uye verapamil (Calan, Isoptin, vamwe). Mimwe mishonga yakawanda inogona zvakare kusangana ne mifepristone, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's Wort.
• udza chiremba wako kana iwe wakambove nekuiswa mutezo kana kana iwe uine kana wakambove uine chirwere chetachiona. Kana iwe uri mukadzi uye usati wavhiyiwa kuti ubvise chibereko chako, udza chiremba wako kana wakambove kana wakambove neropa risingazivikanwe kubuda kweropa, endometrial hyperplasia (kuwanda kwechigadziko chechibereko), kana kenza yemendometri (kenza yemubhedha we chibereko chako). Chiremba wako angangokuudza kuti usatore mifepristone.
• udza chiremba wako kana iwe wakambove nekushaya moyo, nguva yakareba yeQT (chinetso chemwoyo chisingawanzo chinogona kukonzera kusagadzikana kwemoyo, kufenda, kana kufa kamwe kamwe), potasiamu shoma muropa rako, kushomeka kweadrenal (mamiriro ayo maadrenal gland hadzigadziri zvakakwana mamwe mahormone anodikanwa kune akakosha mashandiro emuviri), chirwere chekubuda ropa, kana chiropa, itsvo, kana chirwere chemwoyo.
• udza chiremba wako kana iwe uchiyamwisa.

Usadye grapefruit kana kunwa muto wemazambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Mifepristone inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kurutsa
• muromo wakaoma
• manyoka
• kuvimbiswa
• kubatana kana kurwadziwa kwemhasuru
• kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi
• mapundu
• kuvava

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kusvotwa
• kurasikirwa nenzara
• dzungu kana hurema
• kuneta zvisina kujairika kana kushaya simba
• huta kana kutsamwa
• kuzununguka
• vangadikitira
• mhasuru kushaya simba, aches, kana cramps
• kukurumidza, kusajairika, kana kurova kwehana
• kubuda ropa kusinga tarisirwi kana kusangana nemukadzi
• mweya wekufema

Mifepristone inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti uri kutora mifepristone.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Korlym^®