Ceritinib
Zvemukati
- Usati watora ceritinib,
- Ceritinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
- Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:
Ceritinib inoshandiswa kurapa imwe mhando yekenza isiri-diki yemapapu kenza (NSCLC) iyo yakapararira kune dzimwe nhengo dzomuviri. Ceritinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.
Ceritinib inouya se capsule uye piritsi yekutora nemuromo. Inowanzo kutorwa nechikafu kamwe pazuva. Tora ceritinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ceritinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.
Kana iwe ukarutsa mushure mekutora ceritinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.
Chiremba wako anogona kudzora yako ceritinib, kukubata iwe nemimwe mishonga, kana kukuudza kuti urege kutora ceritinib kwenguva yakati panguva yekurapa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye chero mhedzisiro yaungasangana nayo. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne ceritinib.
Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.
Usati watora ceritinib,
- udza chiremba wako uye wemishonga kana iwe uri weergergic kune ceritinib, chero mimwe mishonga, kana chimwe chezvinhu zvinosanganiswa mumaceritinib capsules kana mapiritsi. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
- udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); anticoagulants ('blood thinner') senge warfarin (Coumadin, Jantoven); beta blockers senge atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Inderal) uye sotalol (Betapace, Sorine, Sotylize); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); mimwe mishonga yehutachiona hwehutachiona hweHIV (HIV) kana kuwana immunodeficiency syndrome (AIDS) senge efavirenz (Sustiva, muAtripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, muCaletra), uye saquinavir (Invirase); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin; clonidine (Catapres, Kapvay); corticosteroids; cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); disopyramide (Norpace); dofetilide (Tikosyn); donepezil (Aricept); dronedarone (Multaq); escitalopram (Lexapro); fentanyl (Abstral, Actiq, Duragesic, Fentora, Subsys); flecainide (Tambocor); fluconazole (Diflucan); haloperidol (Haldol); ibutilide (Corvert); itraconazole (Onmel, Sporanox, Tolsura); ketoconazole; levofloxacin; methadone (Dolophine, Methadose); moxifloxacin (Avelox); nefazodone; ondansetron (Zuplenz, Zofran); pentamidine (Pentam); phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); pioglitazone (Actos, muDuetact, Oseni); procainamide; quinidine (muNuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifater); sildenafil (Revatio); sirolimus (Rapamune); tacrolimus (Astagraf, Prograf); thioridazine; vardenafil (Levitra, Staxyn); uye verapamil (Calan, Covera, Isoptin, Verelan). Mimwe mishonga yakawanda inogona kubatana ne cititinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
- udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's Wort.
- udza chiremba wako kana iwe uine kana wakambove nechirwere cheshuga kana shuga yakakwira muropa, moyo kutadza, kurova kwemoyo zvisina kujairika, QT kuwedzerwa (irregular moyo rhythm iyo inogona kutungamira mukufenda, kurasikirwa kwekuziva, kubatwa, kana kufa kamwe kamwe), yakaderera mwero ye potassium kana magnesium muropa rako, pancreatitis (kuzvimba kwepancreas), kana chiropa chechiropa.
- udza chiremba wako kana iwe uine pamuviri, kana kuronga kuva nepamuviri. Iwe haufanire kuve nepamuviri iwe paunenge uchitora ceritinib. Iwe unozofanirwa kuve nepamuviri bvunzo usati watanga kurapwa, uye iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapwa kwako uye kweinenge mwedzi mitanhatu mushure meyako yekupedzisira dosi. Kana iwe uri murume ane mukadzi mukadzi uyo anogona kuve nepamuviri, iwe unofanirwa kushandisa kuberekwa kudzivirira kudzivirira kubata panguva iwe uchirapa uye kweinenge mwedzi mitatu mushure meyako yekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Ceritinib inogona kukuvadza mwana wako asati aberekwa. Kana iwe kana mumwe wako mukava nepamuviri panguva yekurapa kwenyu ne ceritinib, danai chiremba wako nekukasira.
- udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa-mwana paunenge uchitora ceritinib uye kweanenge mavhiki maviri mushure mekupedzisira kwako.
- kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora ceritinib.
- iwe unofanirwa kuziva kuti iwe unogona kuwana hyperglycemia (kuwedzera mushuga yako yeropa) paunenge uchitora mushonga uyu. Udza chiremba wako nekukasira kana uine chimwe chezviratidzo zvinotevera paunenge uchitora ceritinib: nyota yakanyanya, kuita weti kakawanda, nzara yakanyanyisa, kusaona zvakanaka, kutemwa nemusoro, kunetseka kufunga kana kuisa pfungwa, mweya unonhuwirira kunge muchero, kana kuneta.
Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.
Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana iri mukati maawa gumi nemaviri emutero wako unotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.
Ceritinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
- kusvotwa
- manyoka
- kurutsa
- kuvimbiswa
- kurwadziwa nemudumbu
- chirungurira
- kunetseka kumedza
- kurasikirwa nenzara
- kuonda
- kuneta
- mapundu
- kuvava
- shanduko pane zvakaratidzwa
- mhasuru, bhonzo, ruoko rwekumashure, kana kurwadziwa kwegumbo
- musoro
Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:
- kurwadziwa kuchikamu chepamusoro chepamusoro chedumbu
- kupwanya kusingawanzo kana kubuda ropa
- weti yakasviba
- yero yeganda nemaziso
- kuderera kwechido
- furu-kunge zviratidzo
- kuvava
- mweya wekufema
- fivha, kutonhora, huro, kuora kuri kuramba kuchiita uye kuzara, kana zvimwe zviratidzo zvehutachiona
- kurwadziwa pachifuva kana kusagadzikana
- shanduko mukurova kwemoyo
- kurova kwemoyo
- dzungu
- musoro wakareruka
- kufenda
- kurwadziwa kuri kuenderera kunotangira kumusoro kuruboshwe kana pakati peguvhu asi kunogona kupararira kumashure
- pfari
Ceritinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.
Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).
Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nechiedza, kupisa kwakanyanya uye hunyoro (kwete muchimbuzi).
Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.
Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org
Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira kumwe kuongorora kwebazi kuti atarise mhinduro yemuviri wako kune ceritinib. Chiremba wako acharaira zvekare bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa ne ceritinib.
Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.
Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.
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