Munyori: Janice Evans
Zuva Rekusika: 25 Chikunguru 2021
Gadziridza Zuva: 15 Mbudzi 2024
Anonim
Lenvatinib As Up-front Therapy for Unresectable HCC
Vhidhiyo: Lenvatinib As Up-front Therapy for Unresectable HCC

Zvemukati

Lenvatinib inoshandiswa kurapa imwe mhando yegomarara rekirin'i yakadzoka kana yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kurapwa iodhini ine radioactive. Lenvatinib inoshandiswa zvakare pamwe neeverolimus (Afinitor, Zortress) kurapa renal cell carcinoma (RCC, rudzi rwekenza inotangira muitsvo) kune vanhu vakambowana kurapwa nemumwe chemotherapy mishonga. Lenvatinib inoshandiswawo kurapa hepatocellular carcinoma (HCC; rudzi rwegomarara rechiropa) risingakwanise kurapwa nekuvhiya. Lenvatinib inoshandiswa zvakare pamwe ne pembrolizumab (Keytruda) kurapa imwe mhando yekenza ye endometrium (lining yechibereko) iyo yakapararira kune mamwe mativi emuviri kana kuwedzera munguva kana mushure mekurapwa nemakemikari mishonga kana isingakwanise kurapwa kuvhiya kana radiation radiation. Lenvatinib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.


Lenvatinib anouya sekapuleti kutora nemuromo. Inowanzo kutorwa kamwe chete zuva nezuva kana kana pasina chikafu. Tora lenvatinib panguva dzakatenderedza zuva rimwe nerimwe. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora lenvatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsules akazara; usavhure, kutsenga, kana kuapwanya.

Kana iwe usingakwanise kumedza macapsule, chiise mugirazi diki uye wobva wawedzera pamusoro pepuniki imwe yemvura kana muto wemaapuro. Usatyora kana kupwanya macapsule. Siya makapuleti mumvura kwemaminitsi gumi uye wozomutsa zvirimo kwemaminitsi matatu. Inwa musanganiswa. Mushure mekunwa musanganiswa, wedzera imwe kapuni imwe yemvura kana muto wemaapuro kugirazi. Shandura zvirimo kashoma uye omedza musanganiswa.

Chiremba wako anogona kudzikisira muyero wako welenvatinib kana kukuudza kuti usiye kutora mishonga kwenguva yakati kana zvachose kana ukava nemhedzisiro. Ive neshuwa yekutaura nachiremba wako nezvekuti urikunzwa sei panguva yekurapwa kwako nelenvatinib.


Kureba kwekurapa kwako kunoenderana nekuti unopindura sei kumushonga uye mhedzisiro yaunosangana nayo. Ramba uchitora lenvatinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora lenvatinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora lenvatinib,

  • udza chiremba wako uye wemishonga kana uri weergoria kune lenvatinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumalevatinib capsules. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora.Ive neshuwa yekutaura chero eanotevera: mimwe mishonga yekusajairika kwemwoyo kusanganisira amiodarone (Nexterone, Pacerone), disopyramide (Norpace), procainamide, quinidine (muNuedexta), uye sotalol (Betapace, Betapace AF, Sorine, Sotylize). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe wakambove nekugumburwa, kuwedzerwa kweropa, sitiroko, chirwere chemwoyo, kutemwa nemusoro, shanduko muchiono, kunyanya izvo zvinokonzerwa nekugwamba kweropa, fistula (kubatana zvisina kujairika pakati penhengo mbiri mukati memuviri wako kana pakati pe nhengo nekunze kwemuviri wako), kubvarura pamadziro edumbu rako kana ura, QT nguva yekuwedzeredza (irregular moyo rhythm iyo inogona kutungamira mukufenda, kurasikirwa kwekuziva, kubatwa, kana kufa kamwe kamwe), moyo kutadza, mashoma masosi ye calcium, potasium, kana magnesium muropa rako, matambudziko ekubuda ropa, kana moyo, itsvo, kana chirwere chechiropa. Uyezve udza chiremba wako kana iwe wakamborapwa ne radiation radiation.
  • iwe unofanirwa kuziva kuti lenvatinib inogona kudzora kubereka muvarume nevakadzi. Nekudaro, iwe haufanire kufunga kuti iwe kana mumwe wako haugone kuve nepamuviri. Udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kuve nemimba yekubata usati watanga kurapwa nelenvatinib. Kana iwe uchikwanisa kuve nepamuviri, iwe unofanirwa kushandisa kuberekwa panguva yekurapa kwako nelenvatinib uye kweanenge mavhiki mana mushure mekupedzisira kwako dose. Kana iwe ukava nepamuviri iwe uri kutora lenvatinib, dana chiremba wako nekukurumidza. Lenvatinib inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora lenvatinib
  • udza chiremba wako kana uri kuronga kuvhiyiwa, kusanganisira kuvhiya mazino. Chiremba wako angangokuudza kuti umise kurapwa kwako nelenvatinib mazuva matanhatu mushure mekuvhiyiwa kwako kwakarongwa nekuti kunogona kukanganisa kupora kwemaronda. Chiremba wako anokuudza iwe nguva yekutanga kutora lenvatinib zvakare mushure mekuvhiyiwa kwako.
  • iwe unofanirwa kuziva kuti yako yeropa inogona kuwedzera panguva yekurapa kwako nelenvatinib. Chiremba wako angangotarisa yako yeropa panguva yekurapa kwako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Kana yako inotevera dosi inokodzera mumaawa gumi nemaviri kana kupfuura, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Nekudaro, kana iyo inotevera dhizaini ichatorwa mune asingasviki maawa gumi nemaviri, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Lenvatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kuneta kana kuneta
  • kuputika, kutsvuka, kuchenesa, kana kubvisa ganda pamaoko emichindwe uye chete (s) etsoka
  • kusvotwa
  • kuvimbiswa
  • chirungurira
  • kuderera kwechido
  • kuonda
  • chinja mukugona kuravira chikafu
  • kukosora
  • hoarseness
  • maronda emuromo
  • muromo wakaoma
  • musoro
  • kubatana uye kurwadziwa kwemhasuru
  • kunetseka kurara kana kuramba wakarara
  • kurasikirwa nevhudzi
  • kupindwa nechando
  • kupisa panguva yekuita weti
  • mapundu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mweya wekufema
  • kuzvimba kwemakumbo nemakumbo
  • kurwadziwa pachipfuva
  • chiveve kana kushaya simba kwechiso, ruoko, kana gumbo kune rimwe divi remuviri wako
  • kurwadziwa mumaoko, musana, mutsipa, kana shaya
  • pakarepo, musoro wakakomba
  • kutaura kunonoka kana kuoma
  • kuchinja kamwe kamwe muchiono
  • manyoka akakomba
  • yero yeganda kana maziso
  • kurwadziwa nemudumbu
  • yakasviba (yeti-tema) weti
  • zvituru-zvine zvituru
  • pfari
  • kushaya simba
  • kuvhiringidzika
  • mhuno yakasimba uye inoramba ichibuda ropa
  • kurutsa kweropa
  • nhema, mira, kana zvituru zvine ropa
  • kukosora ropa kana kugwamba kweropa
  • kubuda ropa kwakanyanya kumwedzi
  • kurutsa, manyoka, kana zviratidzo zvekushaya mvura mumuviri
  • maronda asingarape

Lenvatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune lenvatinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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