Macitentan

Zvemukati

• Usati watora macitentan,
• Macitentan inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kutora macitentan uye kufonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

Kune varwere vechikadzi:

Usatore macitentan kana iwe uine nhumbu kana kuronga kuve nepamuviri. Pane njodzi huru yekuti macitentan inokanganisa fetus.

Nekuda kwenjodzi yekukuvara kwechibereko, chirongwa chinonzi OPSUMIT Risk Evaluation uye Mitigation Strategic (OPSUMIT REMS) chakamisikidzwa kuve nechokwadi chekuti mukadzi ane nhumbu haatore macitentan, uye mukadzi iyeye haazove nepamuviri achitora macitentan. Vese vanhukadzi, kusanganisira vakadzi vasingakwanise kubata nhumbu, vanogona kungogamuchira macitentan kana vakanyoreswa neOPSUMIT REMS, vane tsamba kubva kunechiremba uyo akanyoreswa neOPSUMIT REMS, uye zadza tsamba kuresitorendi yakanyoreswa neOPSUMIT REMS.

Chiremba wako achakunyoresa muOPSUMIT REMS. Chiremba wako anokuudza nezve njodzi dze macitentan, kunyanya njodzi dzekuremara kwakakomba kuberekwa kana ukatorwa uine pamuviri. Unofanirwa kusaina pepa rekubvumirwa rine ruzivo unotaura kuti unonzwisisa ruzivo urwu kuitira kuti chiremba wako akunyore.

Chiremba wako anozotarisawo kana uchikwanisa kuve nepamuviri. Kana iwe wasvika pakuyaruka (kana muviri wemwana ukava wakakura mumuviri uye unokwanisa kuve nemwana), uve nechibereko, uye usati wapfuura panguva yekumira ('shanduko muhupenyu' kupera kwemwedzi wekuenda kumwedzi) unofungidzirwa kunge uri mukadzi ndiani anokwanisa kuve nepamuviri, uye uchafanirwa kutevedzera mimwe mitemo yekuwedzera kuti ugamuchire macitentan.

Kune vakadzi vanogona kubata pamuviri:

Iwe unofanirwa kushandisa yakavimbika nhumbu yekuzvarwa mukati mekurapa kwako ne macitentan, uye kwemwedzi mumwe mushure meyako yekupedzisira dosi. Chiremba wako achakuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinotenderwa, uye anokupa ruzivo rwakanyorwa nezve kuberekwa. Muzviitiko zvakawanda iwe unozofanirwa kushandisa maviri mafomu ekudzivirira kuberekwa kuitira kudzivirira nhumbu uchitora macitentan.

Iwe uchafanirwa kutora bvunzo yepamuviri usati watanga kurapwa, mwedzi wega wega panguva yekurapwa, uye mwedzi mumwe mushure meyero yako yekupedzisira kuti ugone kugamuchira macitentan. Chiremba wako anokuraira bvunzo dzepamuviri iwe. Iyo pharmacy haigone kukupa macitentan kwauri kudzamara vasimbisa kuti watora bvunzo dzako dzinodiwa dzepamuviri.

Iwe haufanire kuita bonde risina dziviriro paunenge uchitora macitentan.

Fonera chiremba wako ipapo ipapo kana wakamboita bonde risina kuzvidzivirira, funga kuti kuzvarwa kwako kwakatadza, kurasikirwa nenguva yako, kana kufunga kuti unogona kunge uine nhumbu chero chikonzero. Iye achakurukura sarudzo dzako dzekurapa newe. Usamirira kusvikira musangano wako unotevera kuti ukurukure izvi nachiremba wako.

Udza chiremba wako kana iwe usinganzwisise zvese zvawakaudzwa nezvekudzivirira kuberekwa, kana kana iwe usingafunge kuti unozokwanisa kushandisa nzira dzinogamuchirwa dzekudzivirira kuberekwa nguva dzese panguva yekurapwa kwako.

Kana iwe uri mubereki kana muchengeti wemukadzi anga asati asvika pakuyaruka, tarisa mwana wako nguva nenguva kuti aone kana ari kukura chero zviratidzo zvekuyaruka (mazamu mazamu, vhudzi rebvudzi) uye rega chiremba wake azive nezve chero shanduko.

Kune vese varwere:

Macitentan haiwanikwe kune zvitoro zvekutengesa. Mishonga yako ichatumirwa kwauri kubva kune yakasarudzika pharmacy iyo yakanyoreswa neOPSUMIT REMS. Kana iwe uri munhukadzi asati asvika pakuyaruka kana mukadzi anokwanisa kuve nepamuviri unongogashira anowana mazuva makumi matatu panguva imwe chete. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvekuti uchawana sei mushonga wako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa ne macitentan uye nguva yega yega paunozadza tsamba yako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Macitentan inoshandiswa kugadzirisa zviratidzo zveplmonary arterial hypertension (PAH; kuwedzerwa kweropa mumidziyo inotakura ropa kumapapu). Macitentan ari mukirasi yemishonga inonzi endothelin receptor vanopikisa. Inoshanda nekumisa chiito che endothelin, chinhu chechisikigo chinoita kuti tsinga dzeropa dziderere uye dzinodzivirira kuyerera kweropa kwakajairika kune vanhu vane PAH

Macitentan inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora macitentan kwakatenderedza nguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora macitentan chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora macitentan,

• udza chiremba wako uye wemishonga kana uri weergergic kune macitentan, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi e macitentan. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), clarithromycin (Biaxin, muPrevpac); efavirenz (Sustiva); zvimwe hutachiona hweHIV protease inhibitors senge nelfinavir (Viracept), indinavir (Crixivan), uye ritonavir (Norvir, muKaletra); itraconazole (Onmel, Sporanox); ketoconazole; nefazodone; nevirapine Viramune); phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); uye rifampin (Rifadin, Rifamate, Rifater, Rimactane). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana nemacitentan, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe wakambove kana anemia (mamiriro umo masero matsvuku eropa asingaunze oxygen yakakwana kunhengo) kana chirwere chechiropa.
• usamwisa mukanwa uchinwa mushonga uyu.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume. Taura nachiremba wako nezve njodzi dzekutora macitentan.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Macitentan inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• mhino yakakora
• huro inorwadza
• kukosora
• dzihwa sezviratidzo
• musoro
• kukurumidza, kazhinji, kana kunorwadza weti
• mapundu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kutora macitentan uye kufonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• ganda rinonhuwa
• weti yakasviba
• yero yeganda rako kana maziso
• kurwadziwa kumusoro kwekurudyi chikamu chedumbu rako
• kusvotwa kusinga tsanangurike kana kurutsa
• kurasikirwa nenzara
• kuneta zvakanyanya
• kupindwa nechando
• kuzvimba kwechiso, huro, rurimi, miromo, uye maziso
• kunetseka kumedza kana kufema
• hoarseness
• mweya wekufema, kunyanya kana wakarara pasi
• kukosora pingi, chihwitsi kana ropa
• kuwedzera kusinganzwisisiki kwehuremu
• kuzvimba kwemakumbo kana makumbo

Macitentan inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• musoro
• kusvotwa
• kurutsa

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira bvunzo kuti aone kuti chiropa chako chiri kushanda zvakadii, uye kutarisa kushomeka kweropa usati watanga kurapwa uye nguva nenguva panguva yekurapa kwako ne macitentan.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Opsumit^®