Evolocumab Jekiseni

Zvemukati

• Usati washandisa jekiseni reevolocumab,
• Evolocumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kushandisa evolocumab jekiseni uye fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidza.

Jekiseni reEvolocumab rinoshandiswa kudzikisa njodzi yesitiroko kana chirwere chemwoyo kana kudiwa kwekuvhiyiwa kwekota (CABG) kune vanhu vane chirwere chemoyo. Jekiseni reEvolocumab rinoshandiswawo pamwe nekudya kwega kana musanganiswa nemimwe mishonga inoderedza cholesterol seHMG-CoA reductase inhibitors (statins) kana ezetimbe (Zetia) kudzikisa huwandu hweepoprotein (LDL) cholesterol ('yakaipa cholesterol ') muropa, kusanganisira vanhu vane mhuri heterozygous hypercholesterolemia (HeFH; iyo inogarwa mamiriro umo cholesterol isingakwanise kubviswa mumuviri zvakajairika). Inoshandiswawo pamwe nekuchinja kweshanduro uye mamwe marapirwo ekudzikisa huwandu hwakaderera-huwandu lipoprotein (LDL) cholesterol ('yakaipa cholesterol') muropa mune vanhu vane homozygous mhuri yemhuri hypercholesterolemia (HoFH; iyo nhaka nhaka mamiriro ayo cholesterol haigone kuve kubviswa mumuviri zvakajairika). Evolocumab jekiseni iri mukirasi yemishonga inonzi proprotein convertase subtilisin kexin mhando 9 (PCSK9) inhibitor monoclonal antibody. Inoshanda nekudzivirira kugadzirwa kweLDL cholesterol mumuviri kudzikisa huwandu hwecholesterol iyo inogona kuvaka pamadziro etsinga uye ichivhara kuyerera kweropa kuenda kumoyo, huropi, uye zvimwe zvikamu zvemuviri.

Kuunganidzwa kwecholesterol pamadziro ako etsinga (maitiro anozivikanwa seatherosclerosis) anoderedza kuyerera kweropa uye, nekudaro, iyo oksijeni inopa kune wako moyo, uropi, uye zvimwe zvikamu zvemuviri wako.

Jekiseni reEvolocumab rinouya semhinduro (mvura) mune sirinji yakasarudzika, autoinjector yakasarudzika, uye mune-yemuviri infusor ine yakagadzirirwa cartridge kujekesa subcutaneously (pasi peganda chete). Kana evolocumab jekiseni ichishandiswa kurapa HeFH kana chirwere chemoyo kana kudzikisira njodzi yesitiroko, chirwere chemwoyo, uye coronary arteri kuburikidza nekuvhiya, inowanzojowa vhiki dzese mbiri kana kamwe chete pamwedzi. Kana evolocumab jekiseni ichishandiswa kurapa HoFH, inowanzojowa kamwe chete pamwedzi. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Shandisa evolocumab jekiseni chaizvo sekurairwa. Usashandise zvishoma kana zvishoma zvemushonga uyu kana kuushandisa kazhinji kana kwenguva yakareba kupfuura zvakatemwa nachiremba wako.

Kana iwe uri kushandisa evolocumab jekiseni kamwe chete pamwedzi (420 mg dosi), jekiseni iyo kamwe pamusoro pemaminetsi gumi nepfumbamwe neiyo-pane muviri infusor uye yakatemerwa katuriji yejekiseni yega yega kana jekiseni majekiseni matatu akapatsana imwe mushure meimwe mukati memaminitsi makumi matatu, uchishandisa imwe yakasarudzika sirinji kana yakagadzirirwa autoinjector yejekiseni rega rega.

Jekiseni reEvolocumab rinobatsira kudzora huwandu hwecholesterol uye kudzikisa njodzi yesitiroko, chirwere chemwoyo, kana coronary artery inopfuura nekuvhiya, asi haina kurapa aya mamiriro kana kubvisa njodzi idzi. Enderera kushandisa evolocumab jekiseni kunyangwe iwe uchinzwa zvakanaka. Usarega kushandisa evolocumab jekiseni usingataure nachiremba wako.

Evolocumab jekiseni inouya mune yakasarudzika autoinjector, yakafarirwa majekiseni, uye mune infusor ine yakasarudzika katuriji iyo ine yakakwana mishonga yedosi imwe. Nguva dzose jekiseni evolocumab mune yayo yakasarudzika autoinjector, jekiseni, kana infusor ine yakasarudzika katuriji; usambozvisanganisa nemimwe mishonga. Rasa tsono dzakashandiswa, majekiseni, nemidziyo mumudziyo unodzivira. Taura nachiremba wako kana wemabhizimusi nezve maratidziro aungaita mudziyo usingadzivirirwe.

Unogona jekiseni evolocumab jekiseni pasi peganda pazvidya zvako kana mudumbu nzvimbo, kunze kwenzvimbo ye2-inch yakatenderedza guvhu rako (dumbu bhatani). Kana mumwe munhu achizokuisirai mushonga iwoyo, munhu iyeye anogona kuupinza muchanza chenyu chepamusoro. Shandisa imwe nzvimbo jekiseni rega rega. Usabaya jekiseni revolocumab munzvimbo ine nyoro, yakapwanywa, yakatsvuka, kana yakaoma. Zvakare, usapinda jekiseni munzvimbo dzine mavanga kana anotambanudza mamaki.

Ngwarira kuverenga mirairo yemugadziri yekushandisa iyo inouya nemushonga. Iyi mirairo inotsanangura maitiro ekupinza jekiseni reyolocumab jekiseni. Ive neshuwa yekubvunza wako wemishonga kana chiremba kana iwe kana iye munhu achange achibaiwa jekiseni mune chero mibvunzo nezve maitiro ekubaya uyu mushonga. Maona Mirayiridzo yekushandisa kubva kumugadziri pa https://bit.ly/3jTG7cx.

Bvisa sirinji yakasarudzika kana pre-autoinjector kubva mufiriji uye ibvumidze kudziya kune tembiricha yemukamuri kwemaminitsi makumi matatu usati waishandisa. Bvisa infusor neakafanirwa katuriji kubva mufiriji uye ibvumidze kudziya kune tembiricha yemukati kwemaminitsi makumi mashanu usati waishandisa. Usadziye evolocumab jekiseni mumvura inopisa, microwave, kana kuiisa muzuva.

Usati washandisa jekiseni reevolocumab, tarisa mhinduro yacho padhuze. Iyo mishonga inofanirwa kuve yakajeka kune yakacheneruka yero uye isina yezvinhu zvinoyangarara. Usazungunuse sirinji yakasarudzika, yakagadzirirwa autoinjector, kana infusor ine yakafetwa katuriji ine evolocumab jekiseni.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa jekiseni reevolocumab,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune evolocumab jekiseni, chero mimwe mishonga, latex, rabha, kana chero chipi chinosanganiswa mujekiseni reevolocumab. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove kana chero mamiriro ekurapa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uchishandisa evolocumab jekiseni, fonera chiremba wako.

Idya yakaderera-mafuta, yakaderera-cholesterol chikafu. Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Iwe unogona zvakare kushanyira iyo National Cholesterol Dzidzo Chirongwa (NCEP) webhusaiti kune rumwe ruzivo rwekudya pa: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Kana iwe ukapa evolocumab jekiseni masvondo maviri ega ega uye kana iri mukati memazuva manomwe kubva pane yako yakarasika dhizaini, jekiseni iyo nekukurumidza kana uchinge uchirangarira uye kuenderera yako yenguva dzose dosing purogiramu. Nekudaro, kana paine anopfuura mazuva manomwe kubva pane yako yakarasika dhizaini, ramba uye ramba uchiita yako yenguva dzose dosing purogiramu. Usapinda jekiseni repiri kuti uwane dhosi rakarasika. Dana chiremba wako kana iwe uchinge warasikirwa neipi uye uine mibvunzo nezve zvekuita.

Kana iwe ukabaya evolocumab jekiseni kamwe chete pamwedzi uye kana iri mukati memazuva manomwe kubva pane yako yakarasika yakarongwa dhizaini, jekiseni iyo iwe nekukurumidza kana uchinge uchirangarira uye kuenderera yako yenguva dzose dosing purogiramu. Nekudaro, kana iwe ukabaya evolocumab jekiseni kamwe chete pamwedzi uye kune mazuva anodarika manomwe kubva padosi yako yawakarasa, jekiseni iyo nekukasira uye tanga iyo nyowani dosing purogiramu inoenderana nezuva iri. Usapinda jekiseni repiri kuti uwane dhosi rakarasika. Dana chiremba wako kana iwe uchinge warasikirwa neipi uye uine mibvunzo nezve zvekuita.

Evolocumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsvuka, kuchenesa, kuzvimba, kurwadziwa, kana unyoro panzvimbo yejekiseni
• furu-senge zviratidzo, inomhanya mhino, huro huro, fivha, kana kutonhora
• kurwadziwa kana kupisa panguva yekuita weti
• mhasuru kana kurwadziwa musana
• dzungu
• kurwadziwa nemudumbu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kushandisa evolocumab jekiseni uye fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidza.

• kuvava
• mapundu
• mikoko
• kunetseka kufema kana kumedza
• kuzvimba kwechiso, huro, rurimi, miromo, uye maziso

Evolocumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchishandisa mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze mufiriji, asi usazviisa pachando. Usasiye evolocumab jekiseni kunze kwefiriji kweanopfuura mazuva makumi matatu. Evolocumab jekiseni inogona kuchengetwa mukamuri tembiricha mukatoni yepakutanga kusvika mazuva makumi matatu. Chengeta evolocumab jekiseni kure kubva kune yakajeka mwenje.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune evolocumab jekiseni.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve evolocumab jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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