Cabozantinib (kenza yechiropa uye yeitsvo)

Zvemukati

• Usati watora cabozantinib (Cabometyx),
• Cabozantinib (Cabometyx) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Cabozantinib (Cabometyx) inoshandiswa kurapa epamberi renal cell carcinoma (RCC; mhando yekenza inotanga mumasero eitsvo). Inoshandiswa zvakare pamwe chete nivolumab (Opdivo) kurapa yakakwira RCC kune varwere vasati vagamuchira kurapwa kweRCC. Cabozantinib (Cabometyx) inoshandiswawo kurapa hepatocellular carcinoma (HCC; rudzi rwegomarara rechiropa) muvanhu vakamborapwa ne sorafenib (Nexafar). Cabozantinib (Cabometyx) iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Cabozantinib inowanikwawo sekapisi (Cometriq) kurapa imwe mhando yegomarara rekenza. Iyi monograph inopa chete ruzivo nezve cabozantinib mahwendefa (Cabometyx) yeiyo yepamusoro RCC kana HCC. Kana iwe urikushandisa uyu mushonga wekenza yetachiona, verenga iyo monograph yakanzi cabozantinib (cancer yegomarara).

Cabozantinib (Cabometyx) inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva pazuva risina chinhu, ingangoita 1 awa zvisati zvaitika uye maawa maviri mushure mekudya. Tora cabozantinib (Cabometyx) panenge panguva imwechete mazuva ese. Kureba kwekurapa kwako kunoenderana nekuti muviri wako unopindura sei kumushonga uye nemhedzisiro iwe yaunowana. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora cabozantinib (Cabometyx) chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mahwendefa akazara negirazi izere (8 ounces, 240 mL) emvura. Usaparadzanise, kutsenga, kana kuvapwanya.

Chiremba wako anogona kudzikisa dosi yako ye cabozantinib (Cabometyx) kana zvachose kana kwechinguva kumisa kurapwa kwako kana iwe ukawana zvakakomba mhedzisiro. Ive neshuwa yekutaura nachiremba wako nezvekuti urikunzwa sei panguva yekurapa kwako necabozantinib (Cabometyx).

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora cabozantinib (Cabometyx),

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune cabozantinib (Cabometyx, Cometriq), chero mimwe mishonga, kana chero chipi zvacho chemapiritsi e cabozantinib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera zvinovaka muviri, zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: boceprevir (Victrelis), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), clarithromycin (Biaxin, muPrevpac), conivaptan (Vaprisol), indinavir (Crixivan), itraconazole ( ), ketoconazole, nefazodone, nelfinavir (Viracept), phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, muRifamate, Rifate, Rifater) , muKaletra), saquinavir (Invirase), telithromycin (Ketek), uye voriconazole (Vfend). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana necabozantinib (Cabometyx), saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana uchangobva kubuda ropa risina kujairika kana rakakomba sekukosora ropa, kurutsa ropa, kana zvituru zvine ropa kana nhema, kana uine ronda rakavhurika kana kupora, kana iwe kana wakambove neBP yakakwira, kana chirwere chechiropa.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kuve nepamuviri bvunzo usati watanga kurapwa ne cabozantinib. Iwe haufanire kuve nepamuviri panguva yekurapa kwako uye kwemwedzi mina mushure meiyo dosi yekupedzisira. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe ukava nepamuviri uchitora cabozantinib (Cabometyx), dana chiremba wako nekukurumidza. Cabozantinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Chiremba wako anogona kukuudza kuti usamwisa mukaka panguva yekurapa kwako uye kwemwedzi mina mushure mekupedzisira kwezita rako.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora cabozantinib (Cabometyx).
• kana uri kuvhiyiwa udza chiremba kuti uri kutora cabozantinib (Cabometyx). Chiremba wako angangokuudza kuti rega kutora cabozantinib (Cabometyx) mazuva makumi maviri nemaviri usati wavhiyiwa kana maitiro, uye anokuudza iwe paunofanira kutanga kutora mushonga zvakare.
• iwe unofanirwa kuziva kuti cabozantinib (Cabometyx) inogona kukonzera matambudziko akakomba nesaya yako. Chiremba wemazino anofanira kuongorora mazino ako usati watanga kutora cabozantinib uye nguva dzose panguva yekurapa kwako. Ive neshuwa yekugeza mazino nekuchenesa muromo wako zvakanaka paunenge uchitora cabozantinib (Cabometyx). Taura nachiremba wako usati wawana chero kurapwa kwemazino iwe paunenge uchinwa mushonga uyu. Chiremba wako angangokuudza kuti rega kutora cabozantinib mazuva makumi maviri nemaviri pamberi pekuvhiyiwa mazino.
• iwe unofanirwa kuziva kuti yako yeropa inogona kuwedzera panguva yekurapa kwako necabozantinib. Chiremba wako angangotarisa yako yeropa usati uye panguva yekurapa kwako.

Usamwe jisi remuzambiringa kana kudya grapefruit kana chero chikafu kana zvekuwedzera zvine muchero wemuzambiringa kana muto wemazambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri isingasviki maawa gumi nemaviri kusvikira yako inotevera yakarongwa dhizaini, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Cabozantinib (Cabometyx) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• kusvotwa
• kurutsa
• chinja mukugona kuravira chikafu
• kutsvuka, kuzvimba, maronda, kana kurwadziwa mumuromo mako
• kurasikirwa nenzara
• kuonda
• kuneta zvakanyanya kana kushaya simba
• ganda rakachenuruka
• ganda rakaoma
• mhasuru
• kurwadziwa muzvibatanidzwa, maoko, kana makumbo
• izwi rinochinja kana kushatirwa
• kunonoka kupora ronda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kurwadziwa pachipfuva, kumanikidza, kana kuomesa
• kukosora ropa kana kugwamba kweropa
• kurutsa zvinhu zvine ropa kana zvinoita kunge kofi nzvimbo
• kubuda kumwedzi kunorema kupfuura nguva dzose
• tsvuku kana nhema, tarry chituru
• manyoka
• kubuda zvisina kujairika kana kunorema kubuda ropa kana kupwanya
• nyoro kana inorwadza nzvimbo yedumbu
• inodziya, tsvuku, kuzvimba, kana nyoro maoko kana makumbo
• kuzvimba wakakomberedza maziso, maoko, maoko, makumbo, tsoka, kana makumbo
• furo weti
• kutadza kufema kana kukosora
• pakarepo musoro
• husina musoro kana kufenda
• pfari
• chiveve kana kushaya simba kwechiso, ruoko, kana gumbo kune rimwe divi remuviri wako
• pakarepo dambudziko rekufamba
• matambudziko ekuona pakarepo
• kuvhiringidzika
• kamwe kamwe kunetseka kufunga kana kutaura zvakajeka
• kamwe kamwe kunetsekana nekuenzanisa kana kubatana
• dzungu
• vangadikitira kupfuura zvakajairwa
• marwadzo eshaya
• kurwadziwa nemazino
• kusununguka kwemeno
• matadza akazvimba kana anorwadza
• mapundu
• kutsvuka, kurwadziwa, kuzvimba, kana kuputika pamichindwe kana pasi petsoka
• kuneta zvakanyanya, dzungu, kupera simba, kushaya simba, kusvotwa, kana kurutsa
• yero yeganda kana maziso, kuneta zvakanyanya, kubuda ropa kana kupwanya zviri nyore, kusvotwa kana kurutsa, kurudyi mativi-mudumbu marwadzo, wakasviba weti weti, kuderera kwechido

Cabozantinib (Cabometyx) inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• ndangariro kurasikirwa
• kuvhiringidzika
• kuonda

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwebazi kuti atarise mhinduro yemuviri wako kune cabozantinib (Cabometyx).

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Cabometyx^®