Acalabrutinib

Zvemukati

• Usati watora acalabrutinib,
• Acalabrutinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi rega kutora acalabrutinib uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Acalabrutinib inoshandiswa kurapa vanhu vane mantle cell lymphoma (MCL; kenza inokura nekukurumidza iyo inotanga mumasero ezvirwere zvemuviri) avo vakatorapwa nechero imwe chemotherapy mishonga. Inoshandiswawo yoga kana neobinutuzumab (Gazyva) kurapa chirwere cheLymphocytic leukemia (CLL; rudzi rwekenza inotanga mumasero machena eropa) uye diki lymphocytic lymphoma (SLL: rudzi rwekenza inotanga mumasero machena eropa) . Acalabrutinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Acalabrutinib inouya sekapuleti kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu maawa gumi nemaviri (kaviri pazuva) chero bedzi chiremba wako achikurudzira kuti ugamuchire kurapwa. Tora acalabrutinib panguva dzakatenderedza nguva dzakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora acalabrutinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule akazara negirazi remvura; usavhure, kutsenga, kana kuzvityora.

Chiremba wako anogona kumbomira kurapwa kwenguva pfupi kana zvachose kana kudzikisa dosi yako yeacalabrutinib zvichienderana nemhedzisiro yaunosangana nayo. Ive neshuwa yekutaura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Usarega kutora acalabrutinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora acalabrutinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune acalabrutinib, chero mimwe mishonga, kana chero chinhu chinowanikwa muacalabrutinib capsules. Kumbira wako wemishonga kana kutarisa Ruzivo rweMurwere kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura anticoagulant mishonga ('ropa rakatetepa') senge warfarin (Coumadin); antiplatelet mishonga ('blood thinners') yakadai seaspirin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, muAggrenox), prasugrel (Effient), ticagrelor (Brilinta), uye ticlodipine; diltiazem (Cardizem, Cartia, Diltzac, vamwe); erythromycin (EES, Eryc, Erythrocin, vamwe); fluconazole (Diflucan); itraconazole (Onmel, Sporanox); proton pump inhibitors senge dexlansoprazole (Dexilant), esomeprazole (Nexium, muVimovo), lansoprazole (Prevacid, muPreppac), omeprazole (Prilosec, muYosprala, Zegerid), pantoprazole (Protonix), uye rabeprazole (Aciphex) uye rifampin (Rifadin, Rimactane, muRifater, Rifamate). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana neacalabrutinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga iwe yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
• kana uri kutora cimetidine (Tagamet), famotidine (Pepcid, muDockxis), nizatidine (Axid), kana ranitidine (Zantac) tora acalabrutinib kweinenge maawa maviri usati watora iyi mishonga.
• kana iwe uri kutora antacids (Maalox, Mylanta, Tums, vamwe) tora acalabrutinib kanenge maawa maviri usati kana mushure mekutora iyi mishonga.
• udza chiremba wako kana iwe uine hutachiona kana kuti wakavhiyiwa munguva pfupi yapfuura, kana iwe kana wakambove nechirwere chechiropa kusanganisira hepatitis B, matambudziko nemoyo wako mutinhimira, kana matambudziko ekubuda ropa.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe haufanire kuve nepamuviri iwe paunenge uchitora acalabrutinib. Iwe haufanire kutanga kutora acalabrutinib kudzamara bvunzo yekuzvitakura yakaratidza kuti hauna nhumbu uye iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapwa kwako uye kweinenge vhiki rimwe mushure mekupedzisira kwako dosi Acalabrutinib inogona kukuvadza mwana wako asati aberekwa. Kana iwe ukava nepamuviri uchitora acalabrutinib, dana chiremba wako pakarepo.
• udza chiremba wako kana iwe uchiyamwisa. Chiremba wako anogona kukuudza kuti usayamwisa panguva yekurapa kwako uye kwemavhiki maviri mushure mekupedzisira dosi.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora acalabrutinib. Chiremba wako anogona kukuudza kuti rega kutora acalabrutinib kwenguva yakati pamberi uye mushure mekuvhiyiwa kana maitiro.
• ronga kudzivirira kudzivirirwa zvisina kufanira kana kwenguva yakareba kune chezuva uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen. Acalabrutinib inogona kuita kuti ganda rako rinyatsoziva njodzi dzezuva, uye zvinogona kuwedzera njodzi yako yekuva nekenza yeganda.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana anopfuura maawa matatu apfuura apfuura kubva pawakarasikirwa nedosi, ruka iro rakarasika dosi uye ramba uchiita yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Acalabrutinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kusvotwa
• kurutsa
• kuvimbiswa
• manyoka
• marwadzo emudumbu
• mapundu
• kupwanya kwechiedza kana diki dzvuku kana puruvara paganda
• kubatana kana kurwadziwa kwemhasuru
• kuneta zvakanyanya

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi rega kutora acalabrutinib uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• fivha, huro, chironda, kana zvimwe zviratidzo zvehutachiona
• kukosora, kufema kwekufema, kurwadziwa pachipfuva kana uchifema kana kukosora, fivha
• nekukurumidza kana kusajairika kurova kwemoyo, kurovera moyo, kunzwa musoro wakareruka kana dzungu, kupera simba, kufema kwekufema, kurwadziwa pachipfuva
• kubuda zvisina kujairika kana kwakanyanya kubuda ropa kana kupwanya
• ropa muzvituru zvako kana nhema, zvigaro zvekugara; weti yepingi kana shava; kurutsa ropa kana kofi pasi kurutsa; kukosora ropa
• kunzwa dzungu, kushaya simba, kana kuvhiringidzika; kuchinja mukutaura; kutemwa nemusoro kunotora nguva refu

Acalabrutinib inogona kuwedzera njodzi yako yekuvandudza mamwe kanzira. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Acalabrutinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune acalabrutinib.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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